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  • PL 20 (Tukholmankatu 8)

    00014

    Finland

20032019
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Publications 2003 2019

Combined epithelial marker analysis of tumour budding in stage II colorectal cancer

Slik, K., Blom, S., Turkki, R., Välimäki, K., Kurki, S., Mustonen, H., Haglund, C., Carpén, O., Kallioniemi, O., Korkeila, E., Sundström, J. & Pellinen, T., Jan 2019, In : The Journal of Pathology: Clinical Research. 5, 1, p. 63-78 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL

Hohtari, H., Bruck, O., Blom, S., Turkki, R., Sinisalo, M., Kovanen, P. E., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., Jul 2019, In : Leukemia. 33, 7, p. 1570-1582 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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T-cell inflamed tumor microenvironment predicts favorable prognosis in primary testicular lymphoma

Leivonen, S-K., Pollari, M., Brück, O., Pellinen, T., Autio, M., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Kallioniemi, O., Mustjoki, S. & Leppä, S., Feb 2019, In : Haematologica. 104, 2, p. 338-346 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2018

Immune cell contexture in the bone marrow tumor microenvironment impacts therapy response in CML

Bruck, O., Blom, S., Dufva, O., Turkki, R., Chheda, H., Ribeiro, A., Kovanen, P., Aittokallio, T., Koskenvesa, P., Kallioniemi, O., Porkka, K., Pellinen, T. & Mustjoki, S., Jul 2018, In : Leukemia. 32, 7, p. 1643-1656 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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ITGB1-dependent upregulation of Caveolin-1 switches TGF beta signalling from tumour-suppressive to oncogenic in prostate cancer

Pellinen, T., Blom, S., Sanchez, S., Välimäki, K., Mpindi, J-P., Azegrouz, H., Strippoli, R., Nieto, R., Viton, M., Palacios, I., Turkki, R., Wang, Y., Sanchez-Alvarez, M., Nordling, S., Bützow, A., Mirtti, T., Rannikko, A., Montoya, M. C., Kallioniemi, O. & del Pozo, M. A., 5 Feb 2018, In : Scientific Reports. 8, 1, 14 p., 2338.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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PD-L1(+) tumor-associated macrophages and PD-1(+) tumor-infiltrating lymphocytes predict survival in primary testicular lymphoma

Pollari, M., Brück, O., Pellinen, T., Vähämurto, P., Karjalainen-Lindsberg, M-L., Mannisto, S., Kallioniemi, O., Kellokumpu-Lehtinen, P-L., Mustjoki, S., Leivonen, S-K. & Leppä, S., 31 Oct 2018, In : Haematologica. 103, 11, p. 1908-1914 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer

Bruun, J., Sveen, A., Barros, R., Eide, P. W., Eilertsen, I., Kolberg, M., Pellinen, T., David, L., Svindland, A., Kallioniemi, O., Guren, M. G., Nesbakken, A., Almeida, R. & Lothe, R. A., Sep 2018, In : Molecular oncology. 12, 9, p. 1639-1655 17 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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SMO Inhibition Modulates Cellular Plasticity and Invasiveness in Colorectal Cancer

Magistri, P., Battistelli, C., Strippoli, R., Petrucciani, N., Pellinen, T., Rossi, L., Mangogna, L., Aurello, P., D'Angelo, F., Tripodi, M., Ramacciato, G. & Nigri, G., 2 Feb 2018, In : Frontiers in Pharmacology. 8, 13 p., 956.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017

Cell of Origin Links Histotype Spectrum to Immune Microenvironment Diversity in Non-small-Cell Lung Cancer Driven by Mutant Kras and Loss of Lkb1

Nagaraj, A. S., Lahtela, J., Hemmes, A., Pellinen, T., Blom, S., Devlin, J. R., Salmenkivi, K., Kallioniemi, O., Mäyränpää, M., Narhi, K. & Verschuren, E. W., 17 Jan 2017, In : Cell Reports. 18, 3, p. 673-684 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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High Amount of PD1+TIM3+ T Helper Cells May Predict Poor Outcome in Adult Acute Lymphoblastic Leukemia

Hohtari, H., Bruck, O., Blom, S., Turkki, R., Ribeiro, A., Sinisalo, M., Kovanen, P., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., 2017, p. 3985. 1 p.

Research output: Conference materialsAbstractResearchpeer-review

High Amount of PD-L1+Tumor Associated Macrophages Is Associated with Better Survival in Patients with Primary Testicular Lymphoma

Pollari, M., Bruck, O., Leivonen, S-K., Pellinen, T., Vahamurto, P., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Mustjoki, S. & Leppa, S., 7 Dec 2017, In : Blood. 130, Suppl 1, p. Meeting Abstract: 2761 2 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

IMMUNOLOGICAL CHARACTERIZATION OF PH plus ALL BONE MARROW BY MULTIPLEX IMMUNOHISTOCHEMISTRY

Hohtari, H., Bruck, O., Blom, S., Turkki, R., Ribeiro, A., Sinisalo, M., Kovanen, P., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., 26 Jun 2017, In : Haematologica. 102, p. 654-654 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Low Expression of T/NK-Cell Signature Predicts Poor Survival in Patients with Primary Testicular and Diffuse Large B-Cell Lymphoma

Leivonen, S-K., Pollari, M., Bruck, O., Pellinen, T., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Mustjoki, S. & Leppa, S., 7 Dec 2017, In : Blood. 130, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Orphan G protein-coupled receptor GPRC5A modulates integrin beta 1-mediated epithelial cell adhesion

Bulanova, D. R., Akimov, Y. A., Rokka, A., Laajala, T. D., Aittokallio, T., Kouvonen, P., Pellinen, T. & Kuznetsov, S. G., 2017, In : Cell Adhesion & Migration. 11, 5-6, p. 434-446 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Open Access
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Systems pathology by multiplexed immunohistochemistry and whole-slide digital image analysis

Blom, S., Paavolainen, L., Bychkov, D., Turkki, R., Maki-Teeri, P., Hemmes, A., Valimaki, K., Lundin, J., Kallioniemi, O. & Pellinen, T., 14 Nov 2017, In : Scientific Reports. 7, 13 p., 15580.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Identification of immune cell infiltration in hematoxylin-eosin stained breast cancer samples: Texture-based classification of tissue morphologies

Turkki, R., Linder, N., Kovanen, P. E., Pellinen, T. & Lundin, J., 2016, MEDICAL IMAGING 2016: DIGITAL PATHOLOGY. Gurcan, MN. & Madabhushi, A. (eds.). SPIE - INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, 7 p. 979110. (Proceedings of SPIE; vol. 9791).

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Immune cell profiling in CML bone marrow by multiplex IHC

Bruck, O., Blom, S., Turkki, R., Kovanen, P., Ribeiro, A., Linder, N., Lundin, J., Kallioniemi, O., Pellinen, T. & Mustjoki, S., Nov 2016, In : Annals of Oncology. 27, 1 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

Immune Cell Profiling in CML Bone Marrow By Multiplex Immunohistochemistry

Oscar, B., Blom, S., Turkki, R., Kovanen, P. E., Ribeiro, A., Linder, N., Lundin, J., Kallioniemi, O., Pellinen, T. & Mustjoki, S., 2 Dec 2016, In : Blood. 128, 22, 4 p.

Research output: Contribution to journalMeeting AbstractResearchpeer-review

2015

Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis

Strippoli, R., Loureiro, J., Moreno, V., Benedicto, I., Perez Lozano, M. L., Barreiro, O., Pellinen, T., Minguet, S., Foronda, M., Teresa Osteso, M., Calvo, E., Vazquez, J., Lopez Cabrera, M. & Angel del Pozo, M., Jan 2015, In : EMBO molecular medicine. 7, 1, p. 102-123 22 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Rac1 Nucleocytoplasmic Shuttling Drives Nuclear Shape Changes and Tumor Invasion

Navarro-Lerida, I., Pellinen, T., Sanchez, S. A., Guadamillas, M. C., Wang, Y., Mirtti, T., Calvo, E. & Del Pozo, M. A., 9 Feb 2015, In : Developmental Cell. 32, 3, p. 318-334 17 p.

Research output: Contribution to journalArticleScientificpeer-review

2013

A simple heterogeneous one-step assay for screening estrogenic compounds

Huovinen, T., Rytkonen, K., Lamminmaki, U. & Pellinen, T., Jan 2013, In : Biotechnology Letters. 35, 1, p. 47-53 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Cell-Based Fuzzy Metrics Enhance High-Content Screening (HCS) Assay Robustness

Azegrouz, H., Karemore, G., Torres, A., Alaiz, C. M., Gonzalez, A. M., Nevado, P., Salmeron, A., Pellinen, T., del Pozo, M. A., Dorronsoro, J. R. & Montoya, M. C., Dec 2013, In : Journal of Biomolecular Screening. 18, 10, p. 1270-1283 14 p.

Research output: Contribution to journalArticleScientificpeer-review

2012

A functional genetic screen reveals new regulators of beta 1-integrin activity

Pellinen, T., Rantala, J. K., Arjonen, A., Mpindi, J. P., Kallioniemi, O. & Ivaska, J., 2012, In : Journal of Cell Science. 125, 3, p. 649-661 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Distinct roles of AKT isoforms in regulating beta 1-integrin activity, migration, and invasion in prostate cancer

Virtakoivu, R., Pellinen, T., Rantala, J. K., Perala, M. & Ivaska, J., 1 Sep 2012, In : Molecular Biology of the Cell. 23, 17, p. 3357-3369 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Inhibition of Transforming Growth Factor-Activated Kinase 1 (TAK1) Blocks and Reverses Epithelial to Mesenchymal Transition of Mesothelial Cells

Strippoli, R., Benedicto, I., Perez Lozano, M. L., Pellinen, T., Sandoval, P., Lopez-Cabrera, M. & Angel del Pozo, M., 27 Feb 2012, In : PLoS One. 7, 2

Research output: Contribution to journalArticleScientificpeer-review

Negative regulators of integrin activity

Pouwels, J., Nevo, J., Pellinen, T., Ylanne, J. & Ivaska, J., 15 Jul 2012, In : Journal of Cell Science. 125, 14, p. 3271-3280 10 p.

Research output: Contribution to journalArticleScientificpeer-review

2011

Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

Goetz, J. G., Minguet, S., Navarro-Lerida, I., Jose Lazcano, J., Samaniego, R., Calvo, E., Tello, M., Osteso-Ibanez, T., Pellinen, T., Echarri, A., Cerezo, A., Klein-Szanto, A. J. P., Garcia, R., Keely, P. J., Sanchez-Mateos, P., Cukierman, E. & Del Pozo, M. A., 2011, In : Cell. 146, 1, p. 148-163 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Competitive binding of Rab21 and p120RasGAP to integrins regulates receptor traffic and migration

Mai, A., Veltel, S., Pellinen, T., Padzik, A., Coffey, E., Marjomaki, V. & Ivaska, J., 2011, In : Journal of Cell Biology. 194, p. 291-306 16 p.

Research output: Contribution to journalArticleScientificpeer-review

2008

Expression of mammary derived growth inhibitor (MDGI) results in phenotypic reversal in breast cancer

Nevo, J., Mattila, E., Pellinen, T., Yamamoto, D. L., Sara, H., Iljin, K., Kallioniemi, O., Bono, P., Warri, A. & Ivaska, J., 2008, In : EJC supplements. 6, p. 38-38 1 p.

Research output: Contribution to journalArticleScientificpeer-review

Integrin-Rab21-Rasa1 complex regulates integrin traffic in migrating cells

Mai, A., Pellinen, T. & Ivaska, J., 2008, In : EJC supplements. 6, p. 78-78 1 p.

Research output: Contribution to journalArticleScientificpeer-review

2006

Integrin traffic

Pellinen, T. & Ivaska, J., 2006, In : Journal of Cell Science. 119, p. 3723-3731 9 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Protein-DNA interaction-based detection of small molecules by employing Renilla luciferase fusion protein: Quantitative and generic measurement of tetracyclines with a Renilla luciferase-tagged Tet repressor protein

Pellinen, T., Rytkonen, K., Ristiniemi, N., Karp, M. & Lamminmaki, U., 2006, In : Analytical Biochemistry. 358, p. 301-303 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta 1-integrins

Pellinen, T., Arjonen, A., Vuoriluoto, K., Kallio, K., Fransen, J. A. M. & Ivaska, J., 2006, In : Journal of Cell Biology. 173, p. 767-780 14 p.

Research output: Contribution to journalArticleScientificpeer-review

2005

Negative regulation of EGFR signalling through integrin-alpha(1)beta(1)-mediated activation of protein tyrosine phosphatase TCPTP

Mattila, E., Pellinen, T., Nevo, J., Vuoriluoto, K., Arjonen, A. & Ivaska, J., 2005, In : Nature Cell Biology. 7, p. 78-+ 12 p.

Research output: Contribution to journalArticleScientificpeer-review

2004

A cell-free biosensor for the detection of transcriptional inducers using firefly luciferase as a reporter

Pellinen, T., Huovinen, T. & Karp, M., 2004, In : Analytical Biochemistry. 330, p. 52-57 6 p.

Research output: Contribution to journalArticleScientificpeer-review

2003

Topology of the Erwinia chrysanthemi oligogalacturonate porin KdgM

Pellinen, T., Ahlfors, H., Blot, N. & Condemine, G., 2003, In : Biochemical Journal. 372, p. 329-334 6 p.

Research output: Contribution to journalArticleScientificpeer-review