Research output per year
Research output per year
Personal profile
Education/Academic qualification
Applied Mathematics, PhD, University of Turku
Award Date: 12 Aug 2001
External positions
Professor of Statistics and Applied Mathematics, University of Turku
1 Aug 2015 → …
Fields of Science
- 3111 Biomedicine
- Computational systems medicine
- 111 Mathematics
- Mathematical modeling
- Biomathematics
- 113 Computer and information sciences
- Data mining
- Bioinformatics
- 112 Statistics and probability
- Biostatistics
International and National Collaboration
Publications and projects within past five years.
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Advancements in Rational Multi-Targeted Drug Discovery: Improving the Efficacy-Safety Balance of Small Molecule Cancer Therapeutics
Ravikumar, B., Cichońska, A., Sahni, N., Aittokallio, T. & Rahman, R., 1 Jan 2025, Polypharmacology: Strategies for Multi-Target Drug Discovery. Peters, J.-U. (ed.). Hoboken, New Jersey: Wiley, p. 109-125 17 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › Scientific › peer-review
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Computational drug repurposing: approaches, evaluation of in silico resources and case studies
Tanoli, Z., Fernandez-Torras, A., Özcan, U. O., Kushnir, A., Nader, K. M., Gadiya, Y., Fiorenza, L., Ianevski, A., Vähä-Koskela, M., Miihkinen, M., Seemab, U., Leinonen, H., Seashore-Ludlow, B., Tampere, M., Kalman, A., Ballante, F., Benfenati, E., Saunders, G., Potdar, S. & Garcia, I. G. & 23 others, , 2025, In: Nature Reviews Drug Discovery. 22 p.Research output: Contribution to journal › Review Article › peer-review
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Dual STAT3/STAT5 inhibition as a novel treatment strategy in T-prolymphocytic leukemia: LYMPHOMA
Dechow, A., Timonen, S., Ianevski, A., Jiang, Q., Wahnschaffe, L., Peng, Y., Jungherz, D., Becker, K., Neubauer, H. A., Schönefeldt, S., de Araujo, E., Gunning, P., Fleck, R., Schrader, A., Hallek, M., Pflug, N., Moriggl, R., Aittokallio, T., Mustjoki, S. & Braun, T. & 1 others, , 15 Apr 2025, In: Leukemia. 14 p., 697.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
High-throughput drug screening identifies SMAC mimetics as enhancers of NK-cell cytotoxicity in chronic myeloid leukemia
iCAN Study Group, Nygrén, P. J., Bouhlal, J. O. V., Jokinen, E., Forstén, S., Laajala, E., Dias, D. A. A., Adnan Awad, S., Ianevski, A., Klievink, J., Lähteenmäki, H., Kuusanmäki, H., Myllymäki, M., Kasanen, T., Saeed, K., Lee, D. A., Hjorth-Hansen, H., Aittokallio, T., Dufva, O. & Mustjoki, S., 10 Apr 2025, In: Blood. 145, 15, p. 1670-1686 17 p.Research output: Contribution to journal › Article › Scientific › peer-review
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Scaling up drug combination surface prediction
Huusari, R., Wang, T., Szedmak, S., Dias, D., Aittokallio, T. & Rousu, J., 13 Mar 2025, In: Briefings in Bioinformatics. 26, 2, 11 p., bbaf099.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
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Chronic lymphocytic leukemia: Improving survival and quality of life
Aittokallio, T. (Project manager)
01/03/2025 → 29/02/2028
Project: Research Council of Finland: Co-funded international programme
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Juselius 1-3 Aittokallio 25
Aittokallio, T. (Project manager) & Vakkilainen, S. S. (Participant)
Sigrid Juséliuksen Säätiö @003701165704@
01/05/2024 → 30/04/2026
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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Syöpäs.24-26 Aittokallio,Lääkevasteen m
Aittokallio, T. (Project manager)
Syöpäsäätiö sr Cancerstiftelsen sr
01/01/2024 → 31/12/2026
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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EU HE/RIA/Aittokallio/REMEDI4ALL
Aittokallio, T. (Project manager), Nader, K. M. (Participant), Schulman, A. (Participant) & Tanoli, Z. (Participant)
01/09/2022 → 31/08/2027
Project: EU Horizon Europe: Research and Innovation Actions (HORIZON-RIA)
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Aittokallio NNF synergy 22-26
Aittokallio, T. (Project manager), Akimov, Y. (Participant), Linnavirta, N. M. M. (Participant) & Miettinen, T. (Participant)
01/02/2022 → 31/01/2026
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
Prizes
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Helsinki Challenge
Tang, J. (Recipient), Kurki, S. (Recipient), Aittokallio, T. A. (Recipient), Andersson, E. I. (Recipient), Kulesskiy, E. (Recipient), Kumar, A. (Recipient), Tsallos, D. (Recipient), Majumder, M. (Recipient), Dufva, O. M. J. (Recipient) & Keränen, M. (Recipient), 22 Nov 2017
Prize: Prizes and awards
Activities
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Computational analyses of small molecules activity from phenotypic screens
Aittokallio, T. (Supervisor)
8 Jan 2019Activity: Examination types › Pre-examiner of doctoral thesis
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Bioinformatics analysis of intron retention events associated with the minor spliceosome
Aittokallio, T. (Supervisor)
Oct 2018Activity: Examination types › Pre-examiner of doctoral thesis
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Machine Learning for Systems Pharmacology
Aittokallio, T. (Supervisor)
5 Oct 2018Activity: Examination types › Supervisor or co-supervisor of doctoral thesis
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University of Toronto
Aittokallio, T. (Visiting researcher)
28 Feb 2018 → 26 Apr 2018Activity: Visiting an external institution types › Academic visit to other institution
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Modeling and prediction of advanced prostate cancer
Aittokallio, T. (Supervisor)
16 Nov 2018Activity: Examination types › Supervisor or co-supervisor of doctoral thesis
Press/Media
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Finnish AI solution helps medical staff kill cancer cells
22/12/2020
1 item of Media coverage
Press/Media: Press / Media
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Researchers develop new model to suggest new method to kill cancer cells
06/12/2020
4 items of Media coverage
Press/Media: Press / Media
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AI predicts which drug combinations kill cancer cells
01/12/2020 → 02/12/2020
12 items of Media coverage
Press/Media: Press / Media
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Machine Learning Model Predicts Which Drug Combinations Kill Cancer Cells
02/12/2020
2 items of Media coverage
Press/Media: Press / Media
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