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Personal profile

Education/Academic qualification

Applied Mathematics, PhD, University of Turku

External positions

Professor of Statistics and Applied Mathematics, University of Turku

1 Aug 2015 → …

Keywords

  • 3111 Biomedicine
  • Computational systems medicine
  • 111 Mathematics
  • Mathematical modeling
  • Biomathematics
  • 113 Computer and information sciences
  • Data mining
  • Bioinformatics
  • 112 Statistics and probability
  • Biostatistics

International and National Collaboration Publications and projects within past five years.

Publications 2001 2019

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Menden, M. P., Wang, D., Mason, M. J., Szalai, B., Bulusu, K. C., Guan, Y., Yu, T., Kang, J., Jeon, M., Wolfinger, R., Nguyen, T., Zaslavskiy, M., Abante, J., Abecassis, B. S., Aben, N., Aghamirzaie, D., Aittokallio, T., Akhtari, F. S., Al-lazikani, B., Alam, T. & 280 othersAllam, A., Allen, C., de Almeida, M. P., Altarawy, D., Alves, V., Amadoz, A., Anchang, B., Antolin, A. A., Ash, J. R., Aznar, V. R., Ba-alawi, W., Bagheri, M., Bajic, V., Ball, G., Ballester, P. J., Baptista, D., Bare, C., Bateson, M., Bender, A., Bertrand, D., Wijayawardena, B., Boroevich, K. A., Bosdriesz, E., Bougouffa, S., Bounova, G., Brouwer, T., Bryant, B., Calaza, M., Calderone, A., Calza, S., Capuzzi, S., Carbonell-Caballero, J., Carlin, D., Carter, H., Castagnoli, L., Celebi, R., Cesareni, G., Chang, H., Chen, G., Chen, H., Chen, H., Cheng, L., Chernomoretz, A., Chicco, D., Cho, K-H., Cho, S., Choi, D., Choi, J., Choi, K., Choi, M., Cock, M. D., Coker, E., Cortes-Ciriano, I., Cserzö, M., Cubuk, C., Curtis, C., Daele, D. V., Dang, C. C., Dijkstra, T., Dopazo, J., Draghici, S., Drosou, A., Dumontier, M., Ehrhart, F., Eid, F-E., ElHefnawi, M., Elmarakeby, H., van Engelen, B., Engin, H. B., de Esch, I., Evelo, C., Falcao, A. O., Farag, S., Fernandez-Lozano, C., Fisch, K., Flobak, A., Fornari, C., Foroushani, A. B. K., Fotso, D. C., Fourches, D., Friend, S., Frigessi, A., Gao, F., Gao, X., Gerold, J. M., Gestraud, P., Ghosh, S., Gillberg, J., Godoy-Lorite, A., Godynyuk, L., Godzik, A., Goldenberg, A., Gomez-Cabrero, D., Gonen, M., de Graaf, C., Gray, H., Grechkin, M., Guimera, R., Guney, E., Haibe-Kains, B., Han, Y., Hase, T., He, D., He, L., Heath, L. S., Hellton, K. H., Helmer-Citterich, M., Hidalgo, M. R., Hidru, D., Hill, S. M., Hochreiter, S., Hong, S., Hovig, E., Hsueh, Y-C., Hu, Z., Huang, J. K., Huang, R. S., Hunyady, L., Hwang, J., Hwang, T. H., Hwang, W., Hwang, Y., Isayev, O., Don’t Walk, O. B., Jack, J., Jahandideh, S., Ji, J., Jo, Y., Kamola, P. J., Kanev, G. K., Karacosta, L., Karimi, M., Kaski, S., Kazanov, M., Khamis, A. M., Khan, S. A., Kiani, N. A., Kim, A., Kim, J., Kim, J., Kim, K., Kim, K., Kim, S., Kim, Y., Kim, Y., Kirk, P. D. W., Kitano, H., Klambauer, G., Knowles, D., Ko, M., Kohn-Luque, A., Kooistra, A. J., Kuenemann, M. A., Kuiper, M., Kurz, C., Kwon, M., van Laarhoven, T., Laegreid, A., Lederer, S., Lee, H., Lee, J., Lee, Y. W., Lepp_aho, E., Lewis, R., Li, J., Li, L., Liley, J., Lim, W. K., Lin, C., Liu, Y., Lopez, Y., Low, J., Lysenko, A., Machado, D., Madhukar, N., Maeyer, D. D., Malpartida, A. B., Mamitsuka, H., Marabita, F., Marchal, K., Marttinen, P., Mason, D., Mazaheri, A., Mehmood, A., Mehreen, A., Michaut, M., Miller, R. A., Mitsopoulos, C., Modos, D., Moerbeke, M. V., Moo, K., Motsinger-Reif, A., Movva, R., Muraru, S., Muratov, E., Mushthofa, M., Nagarajan, N., Nakken, S., Nath, A., Neuvial, P., Newton, R., Ning, Z., Niz, C. D., Oliva, B., Olsen, C., Palmeri, A., Panesar, B., Papadopoulos, S., Park, J., Park, S., Park, S., Pawitan, Y., Peluso, D., Pendyala, S., Peng, J., Perfetto, L., Pirro, S., Plevritis, S., Politi, R., Poon, H., Porta, E., Prellner, I., Preuer, K., Pujana, M. A., Ramnarine, R., Reid, J. E., Reyal, F., Richardson, S., Ricketts, C., Rieswijk, L., Rocha, M., Rodriguez-Gonzalvez, C., Roell, K., Rotroff, D., de Ruiter, J. R., Rukawa, P., Sadacca, B., Safikhani, Z., Safitri, F., Sales-Pardo, M., Sauer, S., Schlichting, M., Seoane, J. A., Serra, J., Shang, M-M., Sharma, A., Sharma, H., Shen, Y., Shiga, M., Shin, M., Shkedy, Z., Shopsowitz, K., Sinai, S., Skola, D., Smirnov, P., Soerensen, I. F., Soerensen, P., Song, J-H., Song, S. O., Soufan, O., Spitzmueller, A., Steipe, B., Suphavilai, C., Tamayo, S. P., Tamborero, D., Tang, J., Tanoli, Z-R., Tarres-Deulofeu, M., Tegner, J., Thommesen, L., Tonekaboni, S. A. M., Tran, H., Troyer, E. D., Truong, A., Tsunoda, T., Turu, G., Tzeng, G-Y., Verbeke, L., Videla, S. & Consortium, A-S. D. C. DREAM., 2019, In : Nature Communications. 10, 1

Research output: Contribution to journalArticleScientificpeer-review

DNMT Inhibitors Increase Methylation in the Cancer Genome

Giri, A. K. & Aittokallio, T., 24 Apr 2019, In : Frontiers in Pharmacology. 10, 11 p., 385.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Matrix and Tensor Factorization Methods for Toxicogenomic Modeling and Prediction

Khan, S. A., Aittokallio, T., Scherer, A., Grafström, R. & Kohonen, P., May 2019, Advances in Computational Toxicology: Methodologies and Applications in Regulatory Science. Hong, H. (ed.). Springer Nature Switzerland, p. 57-74 16 p. (Challenges and Advances in Computational Chemistry and Physics; vol. 30).

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer

Tang, J., Gautam, P., Gupta, A., He, L., Timonen, S., Akimov, Y., Wang, W., Szwajda, A., Jaiswal, A., Turei, D., Yadav, B., Kankainen, M., Saarela, J., Saez-Rodriguez, J., Wennerberg, K. & Aittokallio, T., 2019, In : npj Systems Biology and Applications. 5, 1

Research output: Contribution to journalArticleScientificpeer-review

Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy

Haikala, H. M., Anttila, J. M., Marques, E., Raatikainen, T., Ilander, M., Hakanen, H., Ala-Hongisto, H., Savelius, M., Balboa, D., Von Eyss, B., Eskelinen, V., Munne, P., Nieminen, A. I., Otonkoski, T., Schüler, J., Laajala, T. D., Aittokallio, T., Sihto, H., Mattson, J., Heikkilä, P. & 7 othersLeidenius, M., Joensuu, H., Mustjoki, S., Kovanen, P., Eilers, M., Leverson, J. D. & Klefström, J., 6 Feb 2019, In : Nature Communications. 10, 17 p., 620.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Projects 2011 2018

Prizes

Helsinki Challenge

Jing Tang (Recipient), Samu Kurki (Recipient), Tero Aittokallio (Recipient), Emma I. Andersson (Recipient), Evgeny Kulesskiy (Recipient), Ashwini Kumar (Recipient), Dimitrios Tsallos (Recipient), Muntasir Majumder (Recipient), Olli Dufva (Recipient) & Mikko Keränen (Recipient), 22 Nov 2017

Prize: Prizes and awards

Activities 2011 2019

Computational analyses of small molecules activity from phenotypic screens

Tero Aittokallio (Supervisor)
8 Jan 2019

Activity: Examination typesPre-examiner of doctoral thesis

Machine Learning for Systems Pharmacology

Tero Aittokallio (Supervisor)
5 Oct 2018

Activity: Examination typesSupervisor or co-supervisor of doctoral thesis

University of Toronto

Tero Aittokallio (Visiting researcher)
28 Feb 201826 Apr 2018

Activity: Visiting an external institution typesAcademic visit to other institution

Modeling and prediction of advanced prostate cancer

Tero Aittokallio (Supervisor)
16 Nov 2018

Activity: Examination typesSupervisor or co-supervisor of doctoral thesis

Bioinformatics analysis of intron retention events associated with the minor spliceosome

Tero Aittokallio (Supervisor)
Oct 2018

Activity: Examination typesPre-examiner of doctoral thesis