Tero Aittokallio — University of Helsinki

Personal profile

Education/Academic qualification

Applied Mathematics, PhD, University of Turku

External positions

Professor of Statistics and Applied Mathematics, University of Turku

1 Aug 2015 → …

Keywords

3111 Biomedicine
Computational systems medicine
111 Mathematics
Mathematical modeling
Biomathematics
113 Computer and information sciences
Data mining
Bioinformatics
112 Statistics and probability
Biostatistics

International and National Collaboration Publications and projects within past five years.

Publications 2001 2019

92 Article
8 Review Article
3 Meeting Abstract
2 Chapter
5 More

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Menden, M. P., Wang, D., Mason, M. J., Szalai, B., Bulusu, K. C., Guan, Y., Yu, T., Kang, J., Jeon, M., Wolfinger, R., Nguyen, T., Zaslavskiy, M., Abante, J., Abecassis, B. S., Aben, N., Aghamirzaie, D., Aittokallio, T., Akhtari, F. S., Al-lazikani, B., Alam, T. & 280 othersAllam, A., Allen, C., de Almeida, M. P., Altarawy, D., Alves, V., Amadoz, A., Anchang, B., Antolin, A. A., Ash, J. R., Aznar, V. R., Ba-alawi, W., Bagheri, M., Bajic, V., Ball, G., Ballester, P. J., Baptista, D., Bare, C., Bateson, M., Bender, A., Bertrand, D., Wijayawardena, B., Boroevich, K. A., Bosdriesz, E., Bougouffa, S., Bounova, G., Brouwer, T., Bryant, B., Calaza, M., Calderone, A., Calza, S., Capuzzi, S., Carbonell-Caballero, J., Carlin, D., Carter, H., Castagnoli, L., Celebi, R., Cesareni, G., Chang, H., Chen, G., Chen, H., Chen, H., Cheng, L., Chernomoretz, A., Chicco, D., Cho, K-H., Cho, S., Choi, D., Choi, J., Choi, K., Choi, M., Cock, M. D., Coker, E., Cortes-Ciriano, I., Cserzö, M., Cubuk, C., Curtis, C., Daele, D. V., Dang, C. C., Dijkstra, T., Dopazo, J., Draghici, S., Drosou, A., Dumontier, M., Ehrhart, F., Eid, F-E., ElHefnawi, M., Elmarakeby, H., van Engelen, B., Engin, H. B., de Esch, I., Evelo, C., Falcao, A. O., Farag, S., Fernandez-Lozano, C., Fisch, K., Flobak, A., Fornari, C., Foroushani, A. B. K., Fotso, D. C., Fourches, D., Friend, S., Frigessi, A., Gao, F., Gao, X., Gerold, J. M., Gestraud, P., Ghosh, S., Gillberg, J., Godoy-Lorite, A., Godynyuk, L., Godzik, A., Goldenberg, A., Gomez-Cabrero, D., Gonen, M., de Graaf, C., Gray, H., Grechkin, M., Guimera, R., Guney, E., Haibe-Kains, B., Han, Y., Hase, T., He, D., He, L., Heath, L. S., Hellton, K. H., Helmer-Citterich, M., Hidalgo, M. R., Hidru, D., Hill, S. M., Hochreiter, S., Hong, S., Hovig, E., Hsueh, Y-C., Hu, Z., Huang, J. K., Huang, R. S., Hunyady, L., Hwang, J., Hwang, T. H., Hwang, W., Hwang, Y., Isayev, O., Don’t Walk, O. B., Jack, J., Jahandideh, S., Ji, J., Jo, Y., Kamola, P. J., Kanev, G. K., Karacosta, L., Karimi, M., Kaski, S., Kazanov, M., Khamis, A. M., Khan, S. A., Kiani, N. A., Kim, A., Kim, J., Kim, J., Kim, K., Kim, K., Kim, S., Kim, Y., Kim, Y., Kirk, P. D. W., Kitano, H., Klambauer, G., Knowles, D., Ko, M., Kohn-Luque, A., Kooistra, A. J., Kuenemann, M. A., Kuiper, M., Kurz, C., Kwon, M., van Laarhoven, T., Laegreid, A., Lederer, S., Lee, H., Lee, J., Lee, Y. W., Lepp_aho, E., Lewis, R., Li, J., Li, L., Liley, J., Lim, W. K., Lin, C., Liu, Y., Lopez, Y., Low, J., Lysenko, A., Machado, D., Madhukar, N., Maeyer, D. D., Malpartida, A. B., Mamitsuka, H., Marabita, F., Marchal, K., Marttinen, P., Mason, D., Mazaheri, A., Mehmood, A., Mehreen, A., Michaut, M., Miller, R. A., Mitsopoulos, C., Modos, D., Moerbeke, M. V., Moo, K., Motsinger-Reif, A., Movva, R., Muraru, S., Muratov, E., Mushthofa, M., Nagarajan, N., Nakken, S., Nath, A., Neuvial, P., Newton, R., Ning, Z., Niz, C. D., Oliva, B., Olsen, C., Palmeri, A., Panesar, B., Papadopoulos, S., Park, J., Park, S., Park, S., Pawitan, Y., Peluso, D., Pendyala, S., Peng, J., Perfetto, L., Pirro, S., Plevritis, S., Politi, R., Poon, H., Porta, E., Prellner, I., Preuer, K., Pujana, M. A., Ramnarine, R., Reid, J. E., Reyal, F., Richardson, S., Ricketts, C., Rieswijk, L., Rocha, M., Rodriguez-Gonzalvez, C., Roell, K., Rotroff, D., de Ruiter, J. R., Rukawa, P., Sadacca, B., Safikhani, Z., Safitri, F., Sales-Pardo, M., Sauer, S., Schlichting, M., Seoane, J. A., Serra, J., Shang, M-M., Sharma, A., Sharma, H., Shen, Y., Shiga, M., Shin, M., Shkedy, Z., Shopsowitz, K., Sinai, S., Skola, D., Smirnov, P., Soerensen, I. F., Soerensen, P., Song, J-H., Song, S. O., Soufan, O., Spitzmueller, A., Steipe, B., Suphavilai, C., Tamayo, S. P., Tamborero, D., Tang, J., Tanoli, Z-R., Tarres-Deulofeu, M., Tegner, J., Thommesen, L., Tonekaboni, S. A. M., Tran, H., Troyer, E. D., Truong, A., Tsunoda, T., Turu, G., Tzeng, G-Y., Verbeke, L., Videla, S. & Consortium, A-S. D. C. DREAM., 2019, In : Nature Communications. 10, 1

Research output: Contribution to journal › Article › Scientific › peer-review

DNMT Inhibitors Increase Methylation in the Cancer Genome

Giri, A. K. & Aittokallio, T., 24 Apr 2019, In : Frontiers in Pharmacology. 10, 11 p., 385.

Research output: Contribution to journal › Article › Scientific › peer-review

Open Access

File

Matrix and Tensor Factorization Methods for Toxicogenomic Modeling and Prediction

Khan, S. A., Aittokallio, T., Scherer, A., Grafström, R. & Kohonen, P., May 2019, Advances in Computational Toxicology: Methodologies and Applications in Regulatory Science. Hong, H. (ed.). Springer Nature Switzerland, p. 57-74 16 p. (Challenges and Advances in Computational Chemistry and Physics; vol. 30).

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Scientific › peer-review

Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer

Tang, J., Gautam, P., Gupta, A., He, L., Timonen, S., Akimov, Y., Wang, W., Szwajda, A., Jaiswal, A., Turei, D., Yadav, B., Kankainen, M., Saarela, J., Saez-Rodriguez, J., Wennerberg, K. & Aittokallio, T., 2019, In : npj Systems Biology and Applications. 5, 1

Research output: Contribution to journal › Article › Scientific › peer-review

Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy

Haikala, H. M., Anttila, J. M., Marques, E., Raatikainen, T., Ilander, M., Hakanen, H., Ala-Hongisto, H., Savelius, M., Balboa, D., Von Eyss, B., Eskelinen, V., Munne, P., Nieminen, A. I., Otonkoski, T., Schüler, J., Laajala, T. D., Aittokallio, T., Sihto, H., Mattson, J., Heikkilä, P. & 7 othersLeidenius, M., Joensuu, H., Mustjoki, S., Kovanen, P., Eilers, M., Leverson, J. D. & Klefström, J., 6 Feb 2019, In : Nature Communications. 10, 17 p., 620.

Research output: Contribution to journal › Article › Scientific › peer-review

Open Access

File

Projects 2011 2018

1 Active
13 Finished

Elucidation of mechanisms of action of the natural stilbenoid pinosylvin via network pharmacology computational methods

Kibble, M. M., Aittokallio, T., Mäkelä, S., Saarinen, N. & Martinez Chacon , G.

01/01/2014 → …

Project: Research project

Predicting disease specific effects and mechanisms of action of compound combinations in phytotherapy

Kibble, M. M., Aittokallio, T., Tang, J., Sultan Khan, S. & Peddinti, G.

18/05/2015 → 18/12/2017

Project: Research project

Personalizing health and care - creating medically-driven integrative bioinformatics applications focused on oncology, CNS disorders and their comorbidities

Aittokallio, T. & Tang, J.

01/05/2015 → 30/04/2017

Project: Research project

Creating medically-driven integrative bioinformatics applications focused on oncology, CNS disorders and their comorbidities (MedBioinformatics)

Aittokallio, T.

European Commission / Horizon 2020

01/05/2015 → 30/04/2018

Project: Research project

Cancer society of Finland - Individualized drug target combinations: prediction, testing and translation

Tang, J., Aittokallio, T. & Wennerberg, K.

01/01/2015 → 31/12/2016

Project: Research project

Prizes

Helsinki Challenge

Jing Tang (Recipient), Samu Kurki (Recipient), Tero Aittokallio (Recipient), Emma I. Andersson (Recipient), Evgeny Kulesskiy (Recipient), Ashwini Kumar (Recipient), Dimitrios Tsallos (Recipient), Muntasir Majumder (Recipient), Olli Dufva (Recipient) & Mikko Keränen (Recipient), 22 Nov 2017

Prize: Prizes and awards