Research Output per year
Personal profile
Curriculum vitae
Curriculum vitae
I performed my PhD work at the laboratory of Professor Leena Peltonen-Palotie during 1990-1995. This work led to DNA diagnostics of gelsolin-related amyloidosis and revelation of pathogenic processing of mutant gelsolin in neuronal cells. During a 2-year post doc period (1996-1998) at LGN-CNRS, Paris, I developed novel recombinant adenoviral vectors for gene therapy on an experimental model of Parkinson’s disease. Then, my focus shifted towards research on psychiatric traits and I started working as a project leader for large international collaboration on schizophrenia. This work led to understanding the truly heterogeneous background of psychosis as well as connections between genes, cognitive disturbances, and schizophrenia.
From year 2003, my main research focus has been on understanding the molecular mechanisms for disturbed mood and sleep and their relationship. We have revealed association of two genes, DISC1 and DAOA, to intermediate traits for BPD and we were able to replicate some of the findings from earlier genome-wide association studies. We found in a large nation-wide cohort of twins that poor sleep predicted depressed mood in a consistent pattern, while depressed mood did not predict poor sleep, evidencing for the central role of disturbed sleep in mood disorders. We have also found inter-individual variability in sleep quality-related responses to stressful life events and relation of childhood traumatic events to insomnia in adulthood. We found in a systematic association study in a population-based sample that some susceptibility genes associate to depression only in the presence of disturbed sleep. We also found a link between a bipolar susceptibility gene and visual performance, evidencing further for the direct neurobiological link between visual perception, circadian rhythm, and regulation of mood.
Fields of Science
- 3112 Neurosciences
International and National Collaboration
Publications and projects within past five years.
Publications
A specific complaint of insomnia-trouble falling asleep-a target for preventing depression
Paunio, T., 12 May 2020, In : Sleep. 43, 5, 3 p., 081.Research output: Contribution to journal › Editorial › Scientific › peer-review
Development of sleep–wake rhythms during the first year of age
Paavonen, E. J., Morales-Munoz, I., Pölkki, P., Paunio, T., Stenberg, T., Kylliäinen, A., Partonen, T. & Saarenpää-Heikkilä, O., Jun 2020, In : Journal of Sleep Research. 29, 3, 10 p., e12918.Research output: Contribution to journal › Article › Scientific › peer-review
Maternal and paternal depressive symptoms and children's emotional problems at the age of 2 and 5 years: a longitudinal study
Pietikäinen, J. T., Kiviruusu, O., Kylliäinen, A., Pölkki, P., Saarenpää-Heikkilä, O., Paunio, T. & Paavonen, E. J., Feb 2020, In : Journal of Child Psychology & Psychiatry. 61, 2, p. 195-204 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Normal sleep development in infants: findings from two large birth cohorts
Paavonen, E. J., Saarenpää-Heikkilä, O., Morales-Munoz, I., Virta, M., Häkälä, N., Pölkki, P., Kylliäinen, A., Karlsson, H., Paunio, T. & Karlsson, L., May 2020, In : Sleep Medicine. 69, p. 145-154 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Parent-reported early sleep problems and internalising, externalising and dysregulation symptoms in toddlers
Morales-Munoz, I., Lemola, S., Saarenpää-Heikkilä, O., Kylliainen, A., Paunio, T., Polkki, P., Broome, M. R. & Paavonen, E. J., 2020, In : BMJ Paediatrics Open. 4, p. 1-9 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
File
Projects
Tietoisuustaitoja opiskelijoille
Repo, S., Paunio, T., Elovainio, M., Pyörälä, E., Saarinen, J., Peltola, K., Härkönen, T. & Holopainen, M.
01/01/2018 → 31/12/2025
Project: Research project
Studies and wellbeing - Opiskelu ja hyvinvointi -tutkimus
Paunio, T., Pyörälä, E., Saarinen, J., Peltola, K., Härkönen, T., Vartia, J. & Elovainio, M.
09/12/2016 → …
Project: Research project
Lapsen uni ja terveys
Paavonen, J., Paunio, T., Saarenpää-Heikkilä, O., Pölkki, P., Kylliainen, A., Rusanen, E. & Pietiläinen, K.
01/01/2010 → …
Project: Research project
EnGagE: Enhancing Psychiatric Genetic Counselling, Testing, and Training in Europe
Suvisaari, J. & Paunio, T.
Project: Other project
Prizes
Vuoden artikkeli Lääkärilehdessä
Juulia Paavonen (Recipient), Tiina Maria Paunio (Recipient) & Tytti Solantaus (Recipient), 2009
Prize: Prizes and awards
Activities
AMEE 2019
Taina Hintsa (Speaker: Presenter), Anne Helena Monni (Attendee), Eeva Pyörälä (Attendee), Marko Elovainio (Attendee), Saara Repo (Attendee), Tiina Paunio (Attendee)24 Aug 2019 → 28 Aug 2019
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
AMEE 2019
Saara Repo (Speaker: Presenter), Tiina Paunio (Attendee), Eeva Pyörälä (Attendee), Marianne Holopainen (Attendee), panajiota Räsänen (Attendee), Marko Elovainio (Attendee)24 Aug 2019 → 28 Aug 2019
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
AMEE 2017
Tiina Maria Paunio (Poster Presentation), Eeva Pyörälä (Poster Presentation), Jussi Jukka Saarinen (Poster Presentation), Kari Risto Johannes Peltola (Attendee), Jonne Juntura (Poster Presentation), Marko Juhani Elovainio (Poster Presentation)26 Aug 2017 → 30 Aug 2017
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Hosting a Seminar at Evidence-Based Psychotherapy
Tiina Paunio (Chair)11 Jan 2016
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
The 2nd Finnish Symposium of Biological Psychiatry, Finland
Zuzanna Misiewicz (Member of organizing committee), Iiris Maaria Hovatta (Member of organizing committee), Tiina Maria Paunio (Member of organizing committee)19 Dec 2016
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Press / Media
Interview for Anna: Is it something serious?
24/11/2018
1 item of Media coverage
Press/Media: Press / Media