Photo of Timo Laaksonen
  • PL 56 (Viikinkaari 5)

    00014

    Finland

20032020

Research output per year

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Publications

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2020

Endothermic and Exothermic Energy Transfer Made Equally Efficient for Triplet-Triplet Annihilation Upconversion

Isokuortti, J., Allu, S. R., Efimov, A., Vuorimaa-Laukkanen, E., Tkachenko, N. V., Vinogradov, S. A., Laaksonen, T. & Durandin, N. A., 2 Jan 2020, In : Journal of Physical Chemistry Letters. 11, 1, p. 318-324 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Linking volatile and non-volatile compounds to sensory profiles and consumer liking of wild edible Nordic mushrooms

Aisala, H., Manninen, H., Laaksonen, T., Linderborg, K. M., Myoda, T., Hopia, A. & Sandell, M., 30 Jan 2020, In : Food Chemistry. 304, 9 p., 125403.

Research output: Contribution to journalArticleScientificpeer-review

Modulating sustained drug release from nanocellulose hydrogel by adjusting the inner geometry of implantable capsules

Auvinen, V-V., Virtanen, J., Merivaara, A., Virtanen, V., Laurén, P., Tuukkanen, S. & Laaksonen, T., Jun 2020, In : Journal of Drug Delivery Science and Technology. 57, 6 p., 101625.

Research output: Contribution to journalArticleScientificpeer-review

Surface stabilization and dissolution rate improvement of amorphous compacts with thin polymer coatings: can we have it all?

Novakovic, D., Peltonen, L., Isomäki, A. O., Fraser-Miller, S. J., Hagner Nielsen, L., Laaksonen, T. & Strachan, C., 6 Apr 2020, In : Molecular Pharmaceutics. 17, 4, p. 1248-1260 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Taste compound - Nanocellulose interaction assessment by fluorescence indicator displacement assay

Manninen, H., Durandin, N., Hopia, A., Vuorimaa-Laukkanen, E. & Laaksonen, T., 15 Jul 2020, In : Food Chemistry. 318, 6 p., 126511.

Research output: Contribution to journalArticleScientificpeer-review

2019

Critical Sensitizer Quality Attributes for Efficient Triplet-Triplet Annihilation Upconversion with Low Power Density Thresholds

Durandin, N. A., Isokuortti, J., Efimov, A., Vuorimaa-Laukkanen, E., Tkachenko, N. V. & Laaksonen, T., 19 Sep 2019, In : Journal of Physical Chemistry C. 123, 37, p. 22865-22872 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Effects of nanofibrillated cellulose hydrogels on adipose tissue extract and hepatocellular carcinoma cell spheroids in freeze-drying

Auvinen, V-V., Merivaara, A., Kiiskinen, J., Paukkonen, H., Laurén, P., Hakkarainen, T., Koivuniemi, R., Sarkanen, R., Ylikomi, T., Laaksonen, T. & Yliperttula, M., 15 Sep 2019, In : Cryobiology. 91, p. 137-145 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2018

Crystallization Kinetics of an Amorphous Pharmaceutical Compound Using Fluorescence-Lifetime-Imaging Microscopy

Rautaniemi, K., Vuorimaa-Laukkanen, E., Strachan, C. J. & Laaksonen, T., May 2018, In : Molecular Pharmaceutics. 15, 5, p. 1964-1971 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Efficient photon upconversion at remarkably low annihilator concentrations in a liquid polymer matrix: when less is more

Durandin, N. A., Isokuortti, J., Efimov, A., Vuorimaa-Laukkanen, E., Tkachenko, N. V. & Laaksonen, T., 25 Dec 2018, In : Chemical Communications. 54, 99, p. 14029-14032 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Entangled and colloidally stable microcrystalline cellulose matrices in controlled drug release

Dong, Y., Paukkonen, H., Fang, W., Kontturi, E., Laaksonen, T. & Laaksonen, P., Sep 2018, In : International Journal of Pharmaceutics. 548, 1, p. 113-119 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Free amino acids and 5 '-nucleotides in Finnish forest mushrooms

Manninen, H., Rotola-Pukkila, M., Aisala, H., Hopia, A. & Laaksonen, T., 1 May 2018, In : Food Chemistry. 247, p. 23-28 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Halogen-Bond-Assisted Photoluminescence Modulation in Carbazole-Based Emitter

Salunke, J. K., Durandin, N. A., Ruoko, T-P., Candeias, N. R., Vivo, P., Vuorimaa-Laukkanen, E., Laaksonen, T. & Priimagi, A., 26 Sep 2018, In : Scientific Reports. 8, 8 p., 14431.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Pectin and Mucin Enhance the Bioadhesion of Drug Loaded Nanofibrillated Cellulose Films

Lauren, P., Paukkonen, H., Lipiainen, T., Dong, Y., Oksanen, T., Raikkonen, H., Ehlers, H., Laaksonen, P., Yliperttula, M. & Laaksonen, T., Jul 2018, In : Pharmaceutical Research. 35, 7, 14 p., 145.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Understanding Dissolution and Crystallization with Imaging: A Surface Point of View

Novakovic, D., Isomäki, A., Pleunis, B., Fraser-Miller, S. J., Peltonen, L. J., Laaksonen, T. & Strachan, C. J., Nov 2018, In : Molecular Pharmaceutics. 15, 11, p. 5361-5373 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017

Comparison of liposomal drug formulations for transdermal iontophoretic drug delivery

Malinovskaja-Gomez, K., Espuelas, S., Garrido, M. J., Hirvonen, J. & Laaksonen, T., 30 Aug 2017, In : European Journal of Pharmaceutical Sciences. 106, p. 294-301 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Elucidation of Compression-Induced Surface Crystallization in Amorphous Tablets Using Sum Frequency Generation (SFG) Microscopy

Mah, P. T., Novakovic, D., Saarinen, J., Landeghem, S. V., Peltonen, L., Laaksonen, T., Isomäki, A. & Strachan, C. J., 2017, In : Pharmaceutical Research. 34, 5, p. 957-970 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Hydrophobin-nanofibrillated cellulose stabilized emulsions for encapsulation and release of BCS class II drugs

Paukkonen, H., Ukkonen, A., Szilvay, G., Yliperttula, M. & Laaksonen, T., 30 Mar 2017, In : European Journal of Pharmaceutical Sciences. 100, p. 238-248 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Multimodal Nonlinear Optical Imaging for Sensitive Detection of Multiple Pharmaceutical Solid-State Forms and Surface Transformations

Novakovic, D., Saarinen, J., Rojalin, T., Antikainen, O., Fraser-Miller, S., Laaksonen, T., Peltonen, L., Isomäki, A. & Strachan, C. J., 2017, In : Analytical Chemistry. 89, 21, p. 11460-11467 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Nanofibrillar cellulose-alginate hydrogel coated surgical sutures as cell-carrier systems

Lauren, P., Somersalo, P., Pitkanen, I., Lou, Y-R., Urtti, A., Partanen, J., Seppala, J., Madetoja, M., Laaksonen, T., Makitie, A. & Yliperttula, M., 22 Aug 2017, In : PLoS One. 12, 8, 17 p., 0183487.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Nanofibrillar cellulose hydrogels and reconstructed hydrogels as matrices for controlled drug release

Paukkonen, H., Kunnari, M., Lauren, P., Hakkarainen, T., Auvinen, V-V., Oksanen, T., Koivuniemi, R., Yliperttula, M. & Laaksonen, T., 2017, In : International Journal of Pharmaceutics. 532, 1, p. 269-280 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2016

Fluorescence-suppressed time-resolved Raman spectroscopy of pharmaceuticals using complementary metal-oxide semiconductor (CMOS) single-photon avalanche diode (SPAD) detector

Rojalin, T., Kurki, L., Laaksonen, T., Viitala, T., Kostamovaara, J., Gordon, K. C., Galvis, L., Wachsmann-Hogiu, S., Strachan, C. J. & Yliperttula, M., 2016, In : Analytical and Bioanalytical Chemistry. 408, 3, p. 761-774 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Indocyanine Green-Loaded Liposomes for Light-Triggered Drug Release

Lajunen, T., Kontturi, L-S., Viitala, L., Manna, M., Cramariuc, O., Rog, T., Bunker, A., Laaksonen, T., Viitala, T., Murtomäki, L. & Urtti, A., Jun 2016, In : Molecular Pharmaceutics. 13, 6, p. 2095-2107 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Photothermally Triggered Lipid Bilayer Phase Transition and Drug Release from Gold Nanorod and Indocyanine Green Encapsulated Liposomes

Viitala, L., Pajari, S., Lajunen, T., Kontturi, L-S., Laaksonen, T., Kuosmanen, P., Viitala, T., Urtti, A. & Murtomaki, L., 10 May 2016, In : Langmuir. 32, 18, p. 4554-4563 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Real-time Raman based approach for identification of biofouling

Kögler, M., Zhang, B., Cui, L., Shi, Y., Yliperttula, M. L., Laaksonen, T. J., Viitala, T. J. S. & Zhang, K., Jul 2016, In : Sensors and Actuators B: Chemical. 230, p. 411-421 11 p.

Research output: Contribution to journalArticleScientificpeer-review

The effect of surfactants on the dissolution behavior of amorphous formulations

Mah, P. T., Peltonen, L., Novakovic, D., Rades, T., Strachan, C. J. & Laaksonen, T., Jun 2016, In : European Journal of Pharmaceutics and Biopharmaceutics. 103, p. 13-22 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Transdermal iontophoresis of flufenamic acid loaded PLGA nanoparticles

Malinovskaja-Gomez, K., Labouta, H. I., Schneider, M., Hirvonen, J. & Laaksonen, T., 30 Jun 2016, In : European Journal of Pharmaceutical Sciences. 89, p. 154-162 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2015

Differential scanning calorimetry predicts the critical quality attributes of amorphous glibenclamide

Mah, P. T., Laaksonen, T., Rades, T., Peltonen, L. & Strachan, C. J., 1 Dec 2015, In : European Journal of Pharmaceutical Sciences. 80, p. 74-81 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Fabrication of drug-loaded edible carrier substrates from nanosuspensions by flexographic printing

Palo, M., Kolakovic, R., Laaksonen, T., Määttänen, A., Genina, N., Salonen, J., Peltonen, J. & Sandler, N., 30 Oct 2015, In : International Journal of Pharmaceutics. 494, 2, p. 603-610 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Interaction Studies Between Indomethacin Nanocrystals and PEO/PPO Copolymer Stabilizers

Liu, P., Viitala, T., Kartal-Hodzic, A., Liang, H., Laaksonen, T., Hirvonen, J. & Peltonen, L., 2015, In : Pharmaceutical Research. 32, 2, p. 628-639 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Light induced cytosolic drug delivery from liposomes with gold nanoparticles

Lajunen, T., Viitala, L., Kontturi, L-S., Laaksonen, T., Liang, H., Vuorimaa-Laukkanen, E., Viitala, T., Le Guevel, X., Yliperttula, M., Murtomäki, L. & Urtti, A., 10 Apr 2015, In : Journal of Controlled Release. 203, p. 85-98 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Single exosome study reveals subpopulations distributed among cell lines with variability related to membrane content

Smith, Z. J., Lee, C., Rojalin, T., Carney, R. P., Hazari, S., Knudson, A., Lam, K., Saari, H., Lazaro Ibanez, E., Viitala, T., Laaksonen, T., Yliperttula, M. & Wachsmann-Hogiu, S., 7 Dec 2015, In : Journal of Extracellular Vesicles. 4, 15 p., 28533.

Research output: Contribution to journalArticleScientificpeer-review

Solid formulations by a nanocrystal approach: Critical process parameters regarding scale-ability of nanocrystals for tableting applications

Tuomela, A., Laaksonen, T., Laru, J., Antikainen, O., Kiesvaara, J., Ilkka, J., Oksala, O., Rönkkö, S., Järvinen, K., Hirvonen, J. & Peltonen, L., 15 May 2015, In : International Journal of Pharmaceutics. 485, 1-2, p. 77-86 10 p.

Research output: Contribution to journalArticleScientificpeer-review

2014

Brinzolamide nanocrystal formulations for ophthalmic delivery: Reduction of elevated intraocular pressure in vivo

Tuomela, A., Liu, P., Puranen, J., Rönkkö, S., Laaksonen, T., Kalesnykas, G., Oksala, O., Ilkka, J., Laru, J., Järvinen, K., Hirvonen, J. & Peltonen, L., 5 Jun 2014, In : International Journal of Pharmaceutics. 467, 1-2, p. 34-41 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Controlled transdermal delivery of leuprorelin by pulsed iontophoresis and ion-exchange fiber

Malinovskaja, K., Laaksonen, T. & Hirvonen, J., Nov 2014, In : European Journal of Pharmaceutics and Biopharmaceutics. 88, 3, p. 594-601 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Inhibitory activity of the isoflavone Biochanin A on intracellular bacteria of genus Chlamydia and initial development of a buccal formulation

Hanski, L., Genina, N., Uvell, H., Malinovskaja, K., Gylfe, Å., Laaksonen, T., Kolakovic, R., Mäkilä, E., Salonen, J., Hirvonen, J., Elofsson, M., Sandler, N. & Vuorela, P. M., 2014, In : PLoS One. 9, 12, 27 p., 115115.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Nanocrystal-based per-oral itraconazole delivery: Superior in vitro dissolution enhancement versus Sporanox(R) is not realized in in vivo drug absorption

Sarnes, A., Kovalainen, M., Häkkinen, M. R., Laaksonen, T., Laru, J., Kiesvaara, J., Ilkka, J., Oksala, O., Rönkkö, S., Järvinen, K., Hirvonen, J. & Peltonen, L., 28 Apr 2014, In : Journal of Controlled Release. 180, p. 109-116 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Unravelling the Relationship between Degree of Disorder and the Dissolution Behavior of Milled Glibenclamide

Mah, P. T., Laaksonen, T., Rades, T., Aaltonen, J., Peltonen, L. & Strachan, C. J., Jan 2014, In : Molecular Pharmaceutics. 11, 1, p. 234-242 9 p.

Research output: Contribution to journalArticleScientificpeer-review

2013

Coated particle assemblies for the concomitant pulmonary administration of budesonide and salbutamol sulphate

Raula, J., Rahikkala, A., Halkola, T., Pessi, J., Peltonen, L., Hirvonen, J., Jarvinen, K., Laaksonen, T. & Kauppinen, E. I., 2013, In : International Journal of Pharmaceutics. 441, 1-2, p. 248-254 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Dissolution Studies of Poorly Soluble Drug Nanosuspensions in Non-sink Conditions

Liu, P., De Wulf, O., Laru, J., Heikkilä, T., van Veen, B., Kiesvaara, J., Hirvonen, J., Peltonen, L. & Laaksonen, T., Jun 2013, In : AAPS PharmSciTech. 14, 2, p. 748-756 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Drug release from nanoparticles embedded in four different nanofibrillar cellulose aerogels

Valo, H., Arola, S., Laaksonen, P., Torkkeli, M., Peltonen, L., Linder, M. B., Serimaa, R., Kuga, S., Hirvonen, J. & Laaksonen, T., 27 Sep 2013, In : European Journal of Pharmaceutical Sciences. 50, 1, p. 69-77 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Evaluation of drug interactions with nanofibrillar cellulose

Kolakovic, R., Peltonen, L., Laukkanen, A., Hellman, M., Laaksonen, P., Linder, M. B., Hirvonen, J. & Laaksonen, T., 2013, In : European Journal of Pharmaceutics and Biopharmaceutics. 85, 3, p. 1238-1244 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Ion-exchange and iontophoresis-controlled delivery of apomorphine

Malinovskaja, K., Laaksonen, T., Kontturi, K. & Hirvonen, J., Apr 2013, In : European Journal of Pharmaceutics and Biopharmaceutics. 83, 3, p. 477-484 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Modeling solid-state transformations occurring in dissolution testing

Laaksonen, T. & Aaltonen, J., 15 Apr 2013, In : International Journal of Pharmaceutics. 447, 1-2, p. 218-223 6 p.

Research output: Contribution to journalArticleScientificpeer-review

2012

Cellular interactions of surface modified nanoporous silicon particles

Bimbo, L. M., Sarparanta, M., Mäkilä, E., Laaksonen, T., Laaksonen, P., Salonen, J., Linder, M. B., Hirvonen, J., Airaksinen, A. J. & Santos, H. A., 12 Mar 2012, In : Nanoscale. 4, 10, p. 3184-3192 9 p.

Research output: Contribution to journalArticleScientificpeer-review

High photostability and enhanced fluorescence of gold nanoclusters by silver doping

Le Guevel, X., Trouillet, V., Spies, C., Li, K., Laaksonen, T., Auerbach, D., Jung, G. & Schneider, M., 2012, In : Nanoscale. 4, 24, p. 7624-7631 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Intravenous Delivery of Hydrophobin-Functionalized Porous Silicon Nanoparticles: Stability, Plasma Protein Adsorption and Biodistribution

Sarparanta, M., Bimbo, L. M., Rytkönen, J., Mäkilä, E., Laaksonen, T. J., Laaksonen, P., Nyman, M., Salonen, J., Linder, M. B., Hirvonen, J., Santos, H. A. & Airaksinen, A. J., 25 Jan 2012, In : Molecular Pharmaceutics. 9, 3, p. 654-663 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Nanofibrillar cellulose films for controlled drug delivery

Kolakovic, R., Peltonen, L., Laukkanen, A., Hirvonen, J. & Laaksonen, T., Oct 2012, In : European Journal of Pharmaceutics and Biopharmaceutics. 82, 2, p. 308-315 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Spray-dried nanofibrillar cellulose microparticles for sustained drug release

Kolakovic, R., Laaksonen, T., Peltonen, L., Laukkanen, A. & Hirvonen, J., 2012, In : International Journal of Pharmaceutics. 430, 1-2, p. 47-55 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Tablet preformulations of indomethacin-loaded mesoporous silicon microparticles

Tahvanainen, M., Rotko, T., Makila, E., Santos, H. A., Neves, D., Laaksonen, T., Kallonen, A., Hämäläinen, K., Peura, M., Serimaa, R., Salonen, J., Hirvonen, J. & Peltonen, L., 2012, In : International Journal of Pharmaceutics. 422, 1-2, p. 125-131 7 p.

Research output: Contribution to journalArticleScientificpeer-review

The mucoadhesive and gastroretentive properties of hydrophobin-coated porous silicon nanoparticle oral drug delivery systems

Sarparanta, M. P., Bimbo, L. M., Mäkilä, E. M., Salonen, J. J., Laaksonen, P. H., Helariutta, A. M. K., Linder, M. B., Hirvonen, J. T., Laaksonen, T. J., Santos, H. A. & Airaksinen, A. J., 28 Jan 2012, In : Biomaterials. 33, 11, p. 3353-3362 10 p.

Research output: Contribution to journalArticleScientificpeer-review