Research output per year
Research output per year
Personal profile
Fields of Science
- 317 Pharmacy
International and National Collaboration
Publications and projects within past five years.
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Inhibition of prolyl oligopeptidase: A promising pathway to prevent the progression of age-related macular degeneration
Hellinen, L., Koskela, A., Vattulainen, E., Liukkonen, M., Wegler, C., Treyer, A., Handin, N., Svensson, R., Myohanen, T., Poso, A., Kaarniranta, K., Artursson, P. & Urtti, A., Feb 2022, In: Biomedicine & Pharmacotherapy. 146, 15 p., 112501.Research output: Contribution to journal › Article › Scientific › peer-review
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Prolyl oligopeptidase acts as a link between chaperone-mediated autophagy and macroautophagy
Cui, H., Norrbacka, S. M. & Myöhänen, T., Mar 2022, In: Biochemical Pharmacology. 197, 18 p., 114899.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2-Imidazole as a Substitute for the Electrophilic Group Gives Highly Potent Prolyl Oligopeptidase Inhibitors
Pätsi, H. T., Kilpeläinen, T. P., Auno, S., Dillemuth, P. M. J., Arja, K., Lahtela-Kakkonen, M. K., Myöhänen, T. T. & Wallen, E. A. A., 14 Oct 2021, In: ACS Medicinal Chemistry Letters. 12, 10, p. 1578-1584 7 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Deletion or inhibition of prolyl oligopeptidase blocks lithium-induced phosphorylation of GSK3b and Akt by activation of protein phosphatase 2A
Myöhänen, T., Mertens, F., Norrbacka, S. M. & Cui, H., 2021, In: Basic & Clinical Pharmacology & Toxicology. 129, 4, p. 287-296Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Klionsky, D. J., Anwar, T., Eskelinen, E-L., Holmberg, C. I., Jokitalo, E., Kaarniranta, K., Kauppinen, A., Khandelwal, V. K. M., Koskela, A., McWilliams, T. G., Myöhänen, T., Roux, S., Saksela, K., Sarparanta, J. J. & Vihinen, H., 2021, In: Autophagy. 17, 1, p. 1-382 382 p.Research output: Contribution to journal › Review Article › Scientific › peer-review
Open Access
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Prolyylioligopeptidaasi (PREP) - mahdollinen biomarkkeri ja yhteinen lääkekehityskohde useaan hermostoa rappeuttavaan sairauteen?
Myöhänen, T. & Kilpeläinen, T.
01/09/2018 → 31/08/2022
Project: Research project
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Prolyylioligopeptidaasin ligandit - yhteinen hoitomuoto useille hermostoa rappeuttaville sairauksille?
01/10/2016 → 30/09/2018
Project: Research project
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The effects of Prolyl Oligopeptidase (POP) and its inhibition on alpha-synuclein aggregation and Parkinson's disease
Myöhänen, T., Savolainen, M. & Svarcbahs, R.
01/09/2013 → 31/08/2018
Project: Research project
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Uusia hoitomahdollisuuksia Parkinsonin tautiin? - Prolyylioligopeptidaasi ja sen estäminen
01/01/2011 → 31/07/2013
Project: Research project
Prizes
Activities
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Prolyl oligopeptidase on alpha-synuclein aggregation
Timo Myöhänen (Speaker)
26 Feb 2019Activity: Talk or presentation types › Invited talk
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Career as an academic PI
Timo Myöhänen (Speaker)
7 Jun 2019Activity: Talk or presentation types › Invited talk
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FM Johanna Viiri vastaväittöjä
Timo Myöhänen (Supervisor)
9 Aug 2019Activity: Examination types › Opponent of doctoral dissertation
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Epilepsia Open (Journal)
Timo Myöhänen (Reviewer)
2018Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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The Impact of Prolyl Oligopeptidase Inhibitors on Alpha-Synuclein Aggregation
Timo Myöhänen (Speaker)
25 Apr 2018Activity: Talk or presentation types › Invited talk
Press / Media
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Rush testing if genetic clues identify best candidates for Parkinson's surgery
01/09/2017
1 item of Media coverage
Press/Media: Press / Media
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Altered bacterial communities in the gut could be an indicator for Parkinson's disease
29/08/2017
1 item of Media coverage
Press/Media: Press / Media
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A human enzyme can reduce neurotoxic amyloids in a mouse model of dementia
27/06/2017
1 item of Media coverage
Press/Media: Press / Media
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Pre-clinical study suggests Parkinson's could start in gut endocrine cells
15/06/2017
1 item of Media coverage
Press/Media: Press / Media
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Balance and movement improved in animal model of Parkinson's disease
12/06/2017
1 item of Media coverage
Press/Media: Press / Media