Research Output per year
Research Output per year
Personal profile
Fields of Science
- 317 Pharmacy
International and National Collaboration
Publications and projects within past five years.
Publications
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Ang II (Angiotensin II) Conversion to Angiotensin-(1-7) in the Circulation Is POP (Prolyloligopeptidase)-Dependent and ACE2 (Angiotensin-Converting Enzyme 2)-Independent
Serfozo, P., Wysocki, J., Gulua, G., Schulze, A., Ye, M., Liu, P., Jin, J., Bader, M., Myöhänen, T., Garcia Horsman, J. A. & Batlle, D., Jan 2020, In : Hypertension. 75, 1, p. 173-182 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Prolyl oligopeptidase inhibition activates autophagy via protein phosphatase 2A
Svarcbahs, R., Jäntti, M., Kilpeläinen, T., Julku, U., Urvas, L., Kivioja, S., Norrbacka, S. & Myöhänen, T., Jan 2020, In : Pharmacological Research. 151, 16 p., 104558.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
The effect of prolyl oligopeptidase inhibitors on alpha-synuclein aggregation and autophagy cannot be predicted by their inhibitory efficacy
Kilpeläinen, T. P., Hellinen, L., Vrijdag, J., Yan, X., Svarcbahs, R., Vellonen, K-S., Lambeir, A-M., Huttunen, H., Urtti, A., Wallen, E. A. A. & Myohanen, T. T., Aug 2020, In : Biomedicine & Pharmacotherapy. 128, 10 p., 110253.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Behavioural and dopaminergic changes in double mutated human A30P*A53T alpha-synuclein transgenic mouse model of Parkinson´s disease.
Kilpeläinen, T., Julku, U., Svarcbahs, R. & Myöhänen, T., 22 Nov 2019, In : Scientific Reports. 9, 1, 13 p., 17382.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Entsyymien merkitys hermorappeumataudeissa
Kursula, P. & Myöhänen, T., 2019, In : Duodecim. 135, 8, p. 745-752 7 p.Research output: Contribution to journal › Review Article › peer-review
Projects
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Prolyylioligopeptidaasi (PREP) - mahdollinen biomarkkeri ja yhteinen lääkekehityskohde useaan hermostoa rappeuttavaan sairauteen?
Myöhänen, T. & Kilpeläinen, T.
01/09/2018 → 31/08/2022
Project: Research project
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Prolyylioligopeptidaasin ligandit - yhteinen hoitomuoto useille hermostoa rappeuttaville sairauksille?
01/10/2016 → 30/09/2018
Project: Research project
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The effects of Prolyl Oligopeptidase (POP) and its inhibition on alpha-synuclein aggregation and Parkinson's disease
Myöhänen, T., Savolainen, M. & Svarcbahs, R.
01/09/2013 → 31/08/2018
Project: Research project
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Uusia hoitomahdollisuuksia Parkinsonin tautiin? - Prolyylioligopeptidaasi ja sen estäminen
01/01/2011 → 31/07/2013
Project: Research project
Prizes
Activities
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Career as an academic PI
Timo Myöhänen (Speaker)
7 Jun 2019Activity: Talk or presentation types › Invited talk
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FM Johanna Viiri vastaväittöjä
Timo Myöhänen (Supervisor)
9 Aug 2019Activity: Examination types › Opponent of doctoral dissertation
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Prolyl oligopeptidase on alpha-synuclein aggregation
Timo Myöhänen (Speaker)
26 Feb 2019Activity: Talk or presentation types › Invited talk
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The Impact of Prolyl Oligopeptidase Inhibitors on Alpha-Synuclein Aggregation
Timo Myöhänen (Speaker)
25 Apr 2018Activity: Talk or presentation types › Invited talk
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Neurochemistry International (Journal)
Timo Myöhänen (Reviewer)
2018Activity: Publication peer-review and editorial work types › Peer review of manuscripts
Press / Media
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Edistysaskelia Parkinsonin taudin hoidossa
28/04/2017
1 item of Media coverage
Press/Media: Press / Media
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Isoja harppauksia Parkinson-potilaiden hoidossa
01/04/2017
1 Media contribution
Press/Media: Press / Media
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Finnish researchers correct Parkinson's motor symptoms in mice
15/12/2016 → 20/12/2016
4 items of Media coverage
Press/Media: Press / Media
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Suomalaistutkijat korjasivat hiireltä Parkinsonin taudin liikehäiriöt
08/01/2016 → 09/12/2016
8 items of Media coverage
Press/Media: Press / Media