1985 …2019
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Publications 1985 2019

2019

Active Matrix Metalloproteinase-8 Point-of-Care (PoC)/Chairside Mouthrinse Test vs. Bleeding on Probing in Diagnosing Subclinical Periodontitis in Adolescents

Räisänen, I. T., Sorsa, T., van der Schoor, G-J., Tervahartiala, T., van der Schoor, P., Gieselmann, D-R. & Heikkinen, A. M., 23 Mar 2019, In : Diagnostics. 9, 1, 9 p., 34.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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BRAF V600E expression in ameloblastomas-A 36-patient cohort from Helsinki University Hospital

Kelppe, J., Thoren, H., Ristimäki, A., Haglund, C., Sorsa, T. & Hagström, J., May 2019, In : Oral Diseases. 25, 4, p. 1169-1174 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Oral symptoms and oral health-related quality of life in patients with chronic kidney disease from predialysis to posttransplantation

Ruokonen, H., Nylund, K., Meurman, J. H., Heikkinen, A. M., Furuholm, J., Sorsa, T., Roine, R. & Ortiz, F., May 2019, In : Clinical Oral Investigations. 23, 5, p. 2207-2213 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Salivary levels of MPO, MMP-8 and TIMP-1 are associated with gingival inflammation response patterns during experimental gingivitis

Nascimento, G. G., Baelum, V., Sorsa, T., Tervahartiala, T., Skottrup, P. D. & Lopez, R., Mar 2019, In : Cytokine. 115, p. 135-141 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2018

Anti-rheumatic medication and salivary MMP-8, a biomarker for periodontal disease

Äyräväinen, L., Heikkinen, A. M., Kuuliala, A., Ahola, K., Koivuniemi, R., Moilanen, E., Hämäläinen, M., Tervahartiala, T., Meurman, J. H., Leirisalo-Repo, M. & Sorsa, T., Nov 2018, In : Oral Diseases. 24, 8, p. 1562-1571 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
Open Access

Associations of oral fluid MMP-8 with periodontitis in Swiss adult subjects

Mauramo, M., Ramseier, A. M., Mauramo, E., Buser, A., Tervahartiala, T., Sorsa, T. & Waltimo, T., Apr 2018, In : Oral Diseases. 24, 3, p. 449-455 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Cervical biomarkers as predictors of successful induction of labour by Foley catheter

Kruit, H., Heikinheimo, O., Sorsa, T., Juhila, J., Paavonen, J. & Rahkonen, L., 2018, In : Journal of Obstetrics and Gynaecology. 38, 7, p. 927-932 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Diagnosis of Newly Delivered Mothers for Periodontitis with a Novel Oral-Rinse aMMP-8 Point-of-Care Test in a Rural Malawian Population

Leppilahti, J. M., Harjunmaa, U., Järnstedt, J., Mangani, C., Hernández, M., Tervahartiala, T., Lopez, R., Ashorn, U., Ashorn, P., Gieselmann, D-R. & Sorsa, T., 15 Sep 2018, In : Diagnostics. 8, 3, 15 p., 67.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Enhanced Systemic Response of Matrix Metalloproteinases and Their Regulators in Campylobacter and Salmonella Patients

Nilsson, A., Tervahartiala, T., Lennebratt, D., Lannergård, A., Sorsa, T. & Rautelin, H., Dec 2018, In : Diagnostics. 8, 4, 9 p., 82.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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High serum MMP-14 predicts worse survival in gastric cancer

Kasurinen, A., Tervahartiala, T., Laitinen, A., Kokkola, A., Sorsa, T., Böckelman, C. & Haglund, C., 7 Dec 2018, In : PLoS One. 13, 12, 11 p., 0208800.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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High-serum MMP-8 levels are associated with decreased survival and systemic inflammation in colorectal cancer

Sirniö, P., Tuomisto, A., Tervahartiala, T., Sorsa, T., Klintrup, K., Karhu, T., Herzig, K-H., Mäkelä, J., Karttunen, T. J., Salo, T., Mäkinen, M. J. & Vayrynen, J. P., 17 Jul 2018, In : British Journal of Cancer. 119, 2, p. 213-219 7 p.

Research output: Contribution to journalArticleScientificpeer-review

HLA, infections and inflammation in early stages of atherosclerosis in children with type 1 diabetes

Odermarsky, M., Pesonen, E., Sorsa, T., Lernmark, Å., Pussinen, P. J. & Liuba, P., Jan 2018, In : Acta Diabetologica. 55, 1, p. 41-47 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Inflammatory biomarkers in saliva and serum of patients with rheumatoid arthritis with respect to periodontal status

Äyräväinen, L., Heikkinen, A. M., Kuuliala, A., Ahola, K., Koivuniemi, R., Laasonen, L., Moilanen, E., Hämäläinen, M., Tervahartiala, T., Meurman, J. H., Leirisalo-Repo, M. & Sorsa, T., 2018, In : Annals of medicine. 50, 4, p. 333-344 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Matrix Metalloproteinase-8 as an Inflammatory and Prevention Biomarker in Periodontal and Peri-Implant Diseases

Al-Majid, A., Alassiri, S., Rathnayake, N., Tervahartiala, T., Gieselmann, D-R. & Sorsa, T., 16 Sep 2018, In : International journal of Dentistry. 2018, 27 p., 7891323.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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Method for determining risks associated with cardiovascular diseases

Pussinen, P. J., Sorsa, T. A., Salomaa, V., Juhila, J., Korvuo, A. & Tiisala, S., 5 Dec 2018, IPC No. G01N 33/53, 33/68, 33/573, Patent No. FI 127416 B, 31 May 2018, Priority date 29 Sep 2016

Research output: PatentScientific

Molecular forms and fragments of salivary MMP-8 in relation to periodontitis

Gürsoy, U. K., Könönen, E., Tervahartiala, T., Gürsoy, M., Pitkänen, J., Torvi, P., Suominen, A-L., Pussinen, P. & Sorsa, T., Dec 2018, In : Journal of Clinical Periodontology. 45, 12, p. 1421-1428 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Periodontitis and cancer mortality: Register-based cohort study of 68,273 adults in 10-year follow-up

Heikkila, P., But, A., Sorsa, T. & Haukka, J., 1 Jun 2018, In : International Journal of Cancer. 142, 11, p. 2244-2253 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Point-of-Care/Chairside aMMP-8 Analytics of Periodontal Diseases' Activity and Episodic Progression

Räisänen, I. T., Heikkinen, A. M., Siren, E., Tervahartiala, T., Gieselmann, D-R., van der Schoor, G-J., van der Schoor, P. & Sorsa, T., Dec 2018, In : Diagnostics. 8, 4, 5 p., 74.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Probiotic intervention influences the salivary levels of Matrix Metalloproteinase (MMP)-9 and Tissue Inhibitor of metalloproteinases (TIMP)-1 in healthy adults

Jäsberg, H., Tervahartiala, T., Sorsa, T., Söderling, E. & Haukioja, A., Jan 2018, In : Archives of Oral Biology. 85, p. 58-63 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Saliva and serum biomarkers in periodontitis and coronary artery disease

Lahdentausta, L. S. J., Paju, S., Mäntylä, P., Buhlin, K., Tervahartiala, T., Pietiäinen, M., Alfthan, H., Nieminen, M. S., Sinisalo, J., Sorsa, T. A. & Pussinen, P. J., Sep 2018, In : Journal of Clinical Periodontology. 45, 9, p. 1045-1055 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Salivary biomarkers in association with periodontal parameters and the periodontitis risk haplotype

Liukkonen, J., Gursoy, U. K., Könönen, E., Gürsoy, M., Metso, J., Salminen, A., Kopra, E., Jauhiainen, M., Mäntylä, P., Buhlin, K., Paju, S., Sorsa, T., Nieminen, M. S., Lokki, M-L., Sinisalo, J. & Pussinen, P. J., Oct 2018, In : Innate Immunity. 24, 7, p. 439-447 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Serum and saliva biomarkers in cardiovascular diseases and periodontitis: Smoking as a confounding factor

Lahdentausta, L., 2018, Helsinki: Helsingin yliopisto. 128 p.

Research output: ThesisDoctoral ThesisCollection of Articles

Open Access

Serum matrix metalloproteinase-8, tissue inhibitor of metalloproteinase and myeloperoxidase in ischemic stroke

Palm, F., Pussinen, P. J., Safer, A., Tervahartiala, T., Sorsa, T., Urbanek, C., Becher, H. & Grau, A. J., Apr 2018, In : Atherosclerosis. 271, p. 9-14 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Serum MMP-8 and TIMP-1 as prognostic biomarkers in gastric cancer

Laitinen, A., Hagström, J., Mustonen, H., Kokkola, A., Tervahartiala, T., Sorsa, T., Böckelman, C. & Haglund, C., 2018, In : Tumor Biology. 40, 9

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Serum MMP-8 and TIMP-1 predict prognosis in colorectal cancer

Bockelman, C., Beilmann-Lehtonen, I., Kaprio, T., Koskensalo, S., Tervahartiala, T., Mustonen, H., Stenman, U-H., Sorsa, T. & Haglund, C., 22 Jun 2018, In : BMC Cancer. 18, 10 p., 679.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Serum MMP-9 Diagnostics, Prognostics, and Activation in Acute Coronary Syndrome and Its Recurrence

Lahdentausta, L., Leskelä, J., Winkelmann, A., Tervahartiala, T. I., Sorsa, T. A., Pesonen, E. & Pussinen, P. J., 18 Jan 2018, In : Journal of cardiovascular translational research.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Smoking confounds the periodontal diagnostics using saliva biomarkers.

Lahdentausta, L. S. J., Paju, S., Mäntylä, P. A., Buhlin, K., Pietiäinen, M. I., Tervahartiala, T. I., Nieminen, M. S., Sinisalo, J., Sorsa, T. A. & Pussinen, P. J., 2018, (Accepted/In press) In : Journal of Periodontology.

Research output: Contribution to journalArticleScientificpeer-review

SNP Analysis of Caries and Initial Caries in Finnish Adolescents

Raivisto, T., Heikkinen, A., Kovanen, L., Ruokonen, H., Kettunen, K., Tervahartiala, T., Haukka, J. & Sorsa, T., 23 Apr 2018, In : International journal of Dentistry. 2018, 5 p., 1586762.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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The Ability of Quantitative, Specific, and Sensitive Point-of-Care/Chair-Side Oral Fluid Immunotests for aMMP-8 to Detect Periodontal and Peri-Implant Diseases

Alassiri, S., Parnanen, P., Rathnayake, N., Johannsen, G., Heikkinen, A-M., Lazzara, R., Schoor, P. V. D., Schoor, J. G. V. D., Tervahartiala, T., Gieselmann, D. & Sorsa, T., 5 Aug 2018, In : Disease Markers. 2018, 5 p., 1306396.

Research output: Contribution to journalReview ArticleScientificpeer-review

Open Access
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The role of the oral spirochete treponema denticola in periodontitis and orodigestive carcinogenesis

Listyarifah, D., 2018, Helsinki: Helsingin yliopisto. 93 p.

Research output: ThesisDoctoral ThesisCollection of Articles

The use of serum MMP-9 and TIMP-1 in acute coronary syndrome

Lahdentausta, L., Sorsa, T., Pesonen, E. & Pussinen, P., Dec 2018, In : Journal of cardiovascular translational research. 11, 6, p. 526-527 2 p.

Research output: Contribution to journalLetterScientificpeer-review

Open Access
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Treponema denticola chymotrypsin-like protease as associated with HPV-negative oropharyngeal squamous cell carcinoma

Kylmä, A. K., Jouhi, L., Listyarifah, D., Mohamed, H., Mäkitie, A., Remes, S. M., Haglund, C., Atula, T., Nieminen, M. T., Sorsa, T. & Hagström, J., 3 Jul 2018, In : British Journal of Cancer. 119, 1, p. 89-95 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Treponema denticola chymotrypsin-like proteinase is present in early-stage mobile tongue squamous cell carcinoma and related to the clinicopathological features

Listyarifah, D., Nieminen, M. T., Mäkinen, L. K., Haglund, C., Grenier, D., Häyry, V., Nordström, D., Hernandez, M., Yucel-Lindberg, T., Tervahartiala, T., Ainola, M., Sorsa, T. & Hagström, J., Sep 2018, In : Journal of Oral Pathology & Medicine. 47, 8, p. 764-772 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Treponema denticola chymotrypsin-like proteinase may contribute to orodigestive carcinogenesis through immunomodulation

Nieminen, M. T., Listyarifah, D., Hagström, J., Haglund, C., Grenier, D., Nordstrom, D., Uitto, V-J., Hernandez, M., Yucel-Lindberg, T., Tervahartiala, T., Ainola, M. & Sorsa, T., 7 Feb 2018, In : British Journal of Cancer. 118, 3, p. 428-434 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2017

25-hydroxyvitamin D correlates with inflammatory markers in cord blood of healthy newborns

Rosendahl, J., Holmlund-Suila, E., Helve, O., Viljakainen, H., Hauta-alus, H., Valkama, S., Enlund-Cerullo, M., Hytinantti, T., Tervahartiala, T., Sorsa, T., Makitie, O. & Andersson, S., May 2017, In : Pediatric Research. 81, 5, p. 731-735 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

2-Hydroxyisocaproic acid is bactericidal in human dental root canals ex vivo

Sakko, M., Tjaderhane, L., Sorsa, T., Hietala, P. & Rautemaa, R., May 2017, In : International Endodontic Journal. 50, 5, p. 455-463 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Active matrix metalloproteinase-8: Contributor to periodontitis and a missing link between genetics, dentistry, and medicine

Sorsa, T., Heikkinen, A. M., Leppilahti, J., Tervahartiala, T., Nwhator, S., Rathnayake, N., Mäntylä, P., Gieselmann, D-R. & Netuschil, L., 2017, Pathogenesis of Periodontal Diseases: Biological Concepts for Clinicians. Bostanci, N. & Belibasakis, G. N. (eds.). Cham: Springer International Publishing , p. 51-57 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Amniotic Fluid Infection in Preterm Pregnancies with Intact Membranes

Myntti, T., Rahkonen, L., Nupponen, I., Pätäri-Sampo, A., Tikkanen, M., Sorsa, T., Juhila, J., Andersson, S., Paavonen, J. & Stefanovic, V., 2017, In : Disease Markers. 9 p., 8167276.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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A quantitative point-of-care test for periodontal and dental peri-implant diseases

Sorsa, T., Gieselmann, D., Arweiler, N. B. & Hernandez, M., 14 Sep 2017, In : Nature Reviews Disease Primers. 3, 1 p., 17069.

Research output: Contribution to journalArticleScientific

Open Access

Association between serum and oral matrix metalloproteinase-8 levels and periodontal health status

Noack, B., Kipping, T., Tervahartiala, T., Sorsa, T., Hoffmann, T. & Lorenz, K., Oct 2017, In : Journal of Periodontal Research. 52, 5, p. 824-831 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Gingival Inflammation and Salivary or Serum Granulocyte-Secreted Enzymes in Patients With Polycystic Ovary Syndrome

Akcali, A., Bostanci, N., Ozcaka, O., Gumus, P., Ozturk-Ceyhan, B., Tervahartiala, T., Husu, H., Buduneli, N., Sorsa, T. & Belibasakis, G. N., Nov 2017, In : Journal of Periodontology. 88, 11, p. 1145-1152 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Infection and apoptosis associated with inflammation in periodontitis: An immunohistologic study

Listyarifah, D., Al-Samadi, A., Salem, A., Syaify, A., Salo, T., Tervahartiala, T., Grenier, D., Nordstrom, D. C., Sorsa, T. & Ainola, M., Nov 2017, In : Oral Diseases. 23, 8, p. 1144-1154 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Intestinal alkaline phosphatase at the crossroad of intestinal health and disease - a putative role in type 1 diabetes

Lassenius, M. I., Fogarty, C., Blaut, M., Haimila, K., Riittinen, L., Paju, A., Kirveskari, J., Järvelä, J., Ahola, A., Gordin, D., Härmä, M-A., Kumar, A., Hamarneh, S. R., Hodin, R. A., Sorsa, T., Tervahartiala, T., Hoerkkoe, S., Pussinen, P. J., Forsblom, C., Jauhiainen, M. & 4 othersTaskinen, M-R., Groop, P-H., Lehto, M. & FinnDiane Study Grp, Jun 2017, In : Journal of internal medicine. 281, 6, p. 586-600 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Liver and serum expression of matrix metalloproteinases in asymptomatic pediatric liver transplant recipients

Voutilainen, S. H., Kosola, S. K., Tervahartiala, T. I., Sorsa, T. A., Jalanko, H. J. & Pakarinen, M. P., Feb 2017, In : Transplant International. 30, 2, p. 124-133 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Low MMP-8/TIMP-1 reflects left ventricle impairment in takotsubo cardiomyopathy and high TIM P-1 may help to differentiate it from acute coronary syndrome

Parkkonen, O., Nieminen, M. T., Vesterinen, P., Tervahartiala, T., Perola, M., Salomaa, V., Jousilahti, P., Sorsa, T., Pussinen, P. & Sinisalo, J-P., 9 Mar 2017, In : PLoS One. 12, 3, 11 p., 0173371.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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