Photo of Tobias Freitag

Tobias Freitag

  • PL 21 (Haartmaninkatu 3)

    00014

    Finland

20012017
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Personal profile

Curriculum vitae

Tobias Freitag, MD, is a medical researcher and experimental immunologist, trained in gastroenterology and rheumatology. His scientific research is focused on (mucosal) immunology and translational medicine, autoimmune diseases, particularly celiac disease, mechanisms of tolerance to intestinal antigens (food, microbial and self-proteins), regulatory T cell function and rodent disease models. He has been a principal investigator of the Finnish-Swedish NARPANord consortium, investigating pathogenesis of type 1 narcolepsy, and is currently a member of the Academy of Finland Personalized Health-DIGIN Health research consortium, searching for microbial triggers of celiac disease. Starting from 2019, he will contribute as Junior Researcher to the Translational Immunology Research Program at the University of Helsinki, studying therapeutic immune tolerance induction.

 

Keywords

  • 311 Basic medicine
  • Immunology
  • Mucosal Immunology
  • Autoimmunity
  • Oral Tolerance
  • HLA class II
  • Regulatory T cells
  • 312 Clinical medicine
  • Gastroenterology
  • Rheumatology
  • Celiac disease
  • Inflammatory bowel diseases
  • Narcolepsy/cataplexy

International and National Collaboration Publications and projects within past five years.

Publications 2001 2017

Deep sequencing of blood and gut T-cell receptor beta-chains reveals gluten-induced immune signatures in celiac disease

Yohannes, D. A., Freitag, T. L., de Kauwe, A., Kaukinen, K., Kurppa, K., Wacklin, P., Mäki, M., Arstila, T. P., Anderson, R. P., Greco, D. & Saavalainen, P., 21 Dec 2017, In : Scientific Reports. 7, 12 p., 17977.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Antigenic Differences between AS03 Adjuvanted Influenza A (H1N1) Pandemic Vaccines: Implications for Pandemrix-Associated Narcolepsy Risk

Vaarala, O., Vuorela, A., Partinen, M., Baumann, M., Freitag, T. L., Meri, S., Saavalainen, P., Jauhiainen, M., Soliymani, R., Kirjavainen, T., Olsen, P., Saarenpaa-Heikkila, O., Rouvinen, J., Roivainen, M., Nohynek, H., Jokinen, J., Julkunen, I. & Kilpi, T., 15 Dec 2014, In : PLoS One. 9, 12, 23 p., 114361.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4

Junker, Y., Zeissig, S., Kim, S-J., Barisani, D., Wieser, H., Leffler, D. A., Zevallos, V., Libermann, T. A., Dillon, S., Freitag, T. L., Kelly, C. P. & Schuppan, D., 17 Dec 2012, In : Journal of Experimental Medicine. 209, 13, p. 2395-2408 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Human Risk Allele HLA-DRB1*0405 Predisposes Class II Transgenic Ab0 NOD Mice to Autoimmune Pancreatitis

Freitag, T. L., Cham, C., Sung, H-H., Beilhack, G. F., Durinovic-Bello, I., Patel, S. D., Bronson, R. T., Schuppan, D. & Sonderstrup, G., 2010, In : Gastroenterology. 139, 1, p. 281-291 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Gliadin-primed CD4+CD45RBlowCD25- T cells drive gluten-dependent small intestinal damage after adoptive transfer into lymphopenic mice

Freitag, T. L., Rietdijk, S., Junker, Y., Popov, Y., Bhan, A. K., Kelly, C. P., Terhorst, C. & Schuppan, D., 2009, In : Gut. 58, p. 1597-1605 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Projects 2009 2015

Prizes

Research Award

Tobias Freitag (Recipient), 2004

Prize: Prizes and awards

Research Award

Tobias Freitag (Recipient), 2001

Prize: Prizes and awards

Activities 2002 2015

American Journal of Physiology: Gastrointestinal and Liver Physiology (Journal)

Tobias Freitag (Member of editorial board)
2015 → …

Activity: Publication peer-review and editorial work typesEditor of research journal

Invited lecture, Spring meeting of the German Society of Digestive and Metabolic Diseases (DGVS)

Tobias Freitag (Speaker: Presenter)
Jun 2012

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Student teaching - Immunology Lectures - Translational Medicine Master Degree Programme

Tobias Freitag (Speaker: Presenter)
May 2011 → …

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Haartman Institute Seminar Series

Tobias Freitag (Member of organizing committee)
20092012

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

2nd Nordic Meeting on Genetics and Pathogenesis of Immunological Diseases

Tobias Freitag (Member of organizing committee)
9 Sep 200911 Sep 2009

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars