Tobias Freitag

Personal profile

Curriculum vitae

Tobias Freitag, MD, is a medical researcher and experimental immunologist, trained in gastroenterology and rheumatology. His scientific research is focused on (mucosal) immunology and translational medicine, autoimmune diseases, particularly celiac disease, mechanisms of tolerance to intestinal antigens (food, microbial and self-proteins), regulatory T cell function and rodent disease models. He has been a principal investigator of the Finnish-Swedish NARPANord consortium, investigating pathogenesis of type 1 narcolepsy, and is currently a member of the Academy of Finland Personalized Health-DIGIN Health research consortium, searching for microbial triggers of celiac disease. Starting from 2019, he will contribute as Junior Researcher to the Translational Immunology Research Program at the University of Helsinki, studying therapeutic immune tolerance induction.

Fields of Science

3112 Neurosciences

International and National Collaboration Publications and projects within past five years.

Publications

10 Article
4 Conference article
3 Review Article
2 Chapter
2 More
- 1 Meeting Abstract
- 1 Doctoral Thesis

Deep sequencing of blood and gut T-cell receptor beta-chains reveals gluten-induced immune signatures in celiac disease

Yohannes, D. A., Freitag, T. L., de Kauwe, A., Kaukinen, K., Kurppa, K., Wacklin, P., Mäki, M., Arstila, T. P., Anderson, R. P., Greco, D. & Saavalainen, P., 21 Dec 2017, In : Scientific Reports. 7, 12 p., 17977.

Research output: Contribution to journal › Article › Scientific › peer-review

Open Access

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Antigenic Differences between AS03 Adjuvanted Influenza A (H1N1) Pandemic Vaccines: Implications for Pandemrix-Associated Narcolepsy Risk

Vaarala, O., Vuorela, A., Partinen, M., Baumann, M., Freitag, T. L., Meri, S., Saavalainen, P., Jauhiainen, M., Soliymani, R., Kirjavainen, T., Olsen, P., Saarenpaa-Heikkila, O., Rouvinen, J., Roivainen, M., Nohynek, H., Jokinen, J., Julkunen, I. & Kilpi, T., 15 Dec 2014, In : PLoS One. 9, 12, 23 p., 114361.

Research output: Contribution to journal › Article › Scientific › peer-review

Open Access

File

Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4

Junker, Y., Zeissig, S., Kim, S-J., Barisani, D., Wieser, H., Leffler, D. A., Zevallos, V., Libermann, T. A., Dillon, S., Freitag, T. L., Kelly, C. P. & Schuppan, D., 17 Dec 2012, In : Journal of Experimental Medicine. 209, 13, p. 2395-2408 14 p.

Research output: Contribution to journal › Article › Scientific › peer-review

Human Risk Allele HLA-DRB1*0405 Predisposes Class II Transgenic Ab0 NOD Mice to Autoimmune Pancreatitis

Freitag, T. L., Cham, C., Sung, H-H., Beilhack, G. F., Durinovic-Bello, I., Patel, S. D., Bronson, R. T., Schuppan, D. & Sonderstrup, G., 2010, In : Gastroenterology. 139, 1, p. 281-291 11 p.

Research output: Contribution to journal › Article › Scientific › peer-review