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Publications 1993 2019

1993

Human serum, plasma, and platelets stimulate prostacyclin and endothelin-1 synthesis in human vascular endothelial-cells

Mikkola, T., Ristimäki, A., Viinikka, L. & Ylikorkala, O., 1993, In : Life Sciences. 53, p. 283-289 7 p.

Research output: Contribution to journalArticleScientificpeer-review

1995

17-beta-estradiol stimulates prostacyclin, but not endothelin-1, production in human vascular endothelial-cells

Mikkola, T., Turunen, P., Avela, K., Orpana, A., Viinikka, L. & Ylikorkala, O., 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 6, p. 1832-1836 5 p.

Research output: Contribution to journalArticleScientificpeer-review

1996

Effect of physiological concentrations of estradiol on PGI(2) and NO in endothelial cells

Mikkola, T., Ranta, V., Orpana, A., Ylikorkala, O. & Viinikka, L., 1996, In : Maturitas. 25, p. 141-147 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Hirudin stimulates prostacyclin but not endothelin-1 production in cultured human vascular endothelial cells

Turunen, P., Mikkola, T., Ylikorkala, O. & Viinikka, L., 1996, In : Thrombosis Research. 81, p. 635-640 6 p.

Research output: Contribution to journalArticleScientificpeer-review

1997

Culturing of human vascular endothelial cells strongly affects their endothelin-1 and prostacyclin production

Ranta, V., Orpana, A., Mikkola, T., Ylikorkala, O. & Viinikka, L., 1997, In : Molecular and Cellular Biochemistry. 177, p. 251-255 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Reduced viability of human vascular endothelial cells cultured on Matrigel (TM)

Ranta, V., Mikkola, T., Ylikorkala, O., Viinikka, L. & Orpana, A., 1998, In : Journal of Cellular Physiology. 176, p. 92-98 7 p.

Research output: Contribution to journalArticleScientificpeer-review

1999

Estradiol and hormone replacement therapy: regulation of the vasoactive agents derived from human vascular endothelial cells

Mikkola, T., 1999, MENOPAUSE AND THE HEART. LANCASTER: PARTHENON PUBLISHING GROUP LTD, p. 15-19 5 p.

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientific

2001

Cholesterol efflux potential of serum from atherogenic diet-fed cynomolgus monkeys after long-term tibolone treatment or traditional hormone replacement therapy

Mikkola, T., Anthony, M. S., Clarkson, T. B. & St Clair, R. W., 2001, In : FASEB Journal. 15, p. A248-A248 1 p.

Research output: Contribution to journalArticleScientificpeer-review

2002

Comparison of tibolone and conjugated equine Estrogens effects on carotid arterv atherosclerosis of postmenopausal monkeys

Clarkson, T. B., Anthony, M. S., Mikkola, T. & St Clair, R. W., 2002, In : Stroke. 33, p. 2700-2703 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Estradiol reduces basal and cytokine induced monocyte adhesion to endothelial cells

Mikkola, T. & Clair, R. W. S., 2002, In : Maturitas. 41, p. 313-319 7 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Estrogen replacement therapy, atherosclerosis, and vascular function

Mikkola, T. & Clarkson, T. B., 2002, In : Cardiovascular Research. 53, p. 605-619 15 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

Serum cholesterol efflux potential in postmenopausal monkeys treated with tibolone or conjugated estrogens

Mikkola, T., Anthony, M. S., Clarkson, T. B. & St Clair, R. W., 2002, In : Metabolism, clinical and experimental. 51, p. 523-530 8 p.

Research output: Contribution to journalArticleScientificpeer-review

2003

Estrogeeni ja sydän- ja verisuonisairaudet

Mikkola, T. & Tikkanen, M. J., 2003, In : Duodecim. p. 2191-2197

Research output: Contribution to journalReview ArticleScientificpeer-review

Serum cholesterol efflux potential is an independent predictor of coronary artery atherosclerosis

Mikkola, T., Anthony, M. S., Clarkson, T. B. & St Clair, R. W., 2003, In : Atherosclerosis. Supplements. 170, p. 31-38 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Postmenopausal hormone therapy before the Women's Health Initiative study: what consequences?

Mikkola, T., Clarkson, T. B. & Notelovitz, M., 2004, In : Annals of Internal Medicine. 36, p. 402-413 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Determination of plasma genistein fatty acid esters following administration of genistein or genistein 4'7-O-dioleate in monkeys

Badeau, M., Tikkanen, M. J., Appt, S. E., Adlercreutz, H., Clarkson, T. B., Hoikkala, A., Wähälä, K. & Mikkola, T. S., 2005, In : Biochimica and Biophysica Acta. Molecular and Cell Biology of Lipids. 1738, p. 115-120 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Hormone therapy and cardiovascular disease - still much to be learnt

Mikkola, T. & Ylikorkala, O., 2005, In : Gynecological Endocrinology. 20, 2, p. 116-120 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Is the pregnancy hormone relaxin an important player in human heart failure?

Kupari, M., Mikkola, T. S., Turto, H. & Lommi, J., 2005, In : European Journal of Heart Failure. 7, 2, p. 195-198 4 p.

Research output: Contribution to journalArticleScientificpeer-review

2006

Coronary heart disease and postmenopausal hormone therapy: conundrum explained by timing? [editorial]

Mikkola, T. & Clarkson, T. B., 2006, In : Journal of Women's Health. 15, 1, p. 51-53 3 p.

Research output: Contribution to journalArticleScientific

Serum cholesterol efflux potential in postmenopausal women treated with isolated isoflavones

Törmälä, R., Nikander, E., Tiitinen, A., Väisänen-Tommiska, M., Ylikorkala, O. & Mikkola, T., 2006, In : Menopause. 13, 1, p. 96-101 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Vasoactive intestinal peptide-release from the heart and response in heart failure due to left ventricular pressure overload

Kupari, M., Mikkola, T., Turto, H., Lommi, J. & Ylikorkala, O., 2006, In : European Journal of Heart Failure. 8, 4, p. 361-365 5 p.

Research output: Contribution to journalArticleScientificpeer-review

2007

Effect of isolated isoflavone supplementation on ABCA1-dependent cholesterol efflux potential in postmenopausal women

Badeau, R., Jauhiainen, M., Metso, J., Nikander, E., Tikkanen, M. J., Ylikorkala, O. & Mikkola, T., 2007, In : Menopause. 14, 2, p. 293-299 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Estradiol fatty acid esters in adipose tissue and serum of pregnant and pre- and postmenopausal women

Badeau, M., Vihma, V., Mikkola, T., Tiitinen, A. & Tikkanen, M. J., 2007, In : Journal of Clinical Endocrinology and Metabolism. 92, 11, p. 4327-4331 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Individual differences in equol production capability modulate blood pressure in tibolone-treated postmenopausal women: lack of effect of soy supplementation

Törmälä, R., Appt, S., Clarkson, T. B., Tikkanen, M. J., Ylikorkala, O., Mikkola, T. & Tikkanen, M. J., 2007, In : Climacteric. 10, 6, p. 471-479 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Management of cardiovascular risk in the peri-menopausal woman: a consensus statement of European cardiologists and gynaecologists

Collins, P., Rosano, G., Casey, C., Daly, C., Gambacciani, M., Hadji, P., Kaaja, R., Mikkola, T., Palacios, S., Preston, R., Simon, T., Stevenson, J. & Stramba-Badiale, M., 2007, In : European Heart Journal. 28, 16, p. 2028-2040 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Vaihdevuosien hormonihoito: miksi hyvät uutiset eivät ylitä uutiskynnystä? : [pääkirjoitus]

Mikkola, T., 2007, In : Duodecim. 123, 17, p. 2049-2050 2 p.

Research output: Contribution to journalArticleScientific

Equol production capability is associated with favorable vascular function in postmenopausal women using tibolone; no effect with soy supplementation

Törmälä, R., Appt, S., Clarkson, T. B., Groop, P. H., Rönnback, M., Ylikorkala, O. & Mikkola, T., 2008, In : Atherosclerosis. 198, 1, p. 174-178 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Impact of soy supplementation on sex steroids and vascular inflammation markers in postmenopausal women using tibolone: role of equol production capability

Törmälä, R., Appt, S., Clarkson, T. B., Mueck, A. O., Seeger, H., Mikkola, T. & Ylikorkala, O., 2008, In : Climacteric. 11, 5, p. 409-415 7 p.

Research output: Contribution to journalArticleScientificpeer-review

One screening magnetic resonance imaging sequence in evaluation of chondral and meniscal lesions of the knee: a pilot stydy

Kuikka, P-I., Böstman, O., Kiuru, M. J., Salminen, S., Mikkola, S. & Pihlajamäki, H., 2008, In : The Open Orthopaedics Journal. 2, p. 19-22 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Soy-tibolone combination: effect on lipids in postmenopausal monkeys and women

Appt, S. E., Törmälä, R., Franke, A. A., Mikkola, T., Tikkanen, M. J., Ylikorkala, O. & Clarkson, T. B., 2008, In : Maturitas. 60, 3-4, p. 216-222 7 p.

Research output: Contribution to journalArticleScientificpeer-review

Aging, menopause, cardiovascular disease and HRT

Archer, D. F., Arnal, J-F., Birkhaeuser, M., Bucciarelli, P., Canonico, M., Carmina, E., de Villiers, T., Gambacciani, M., Hodis, H., Laurent, S., Lobo, R., Mendelsohn, M., Mikkola, T., Nappi, R. E., Panay, N., Pines, A., Rosano, G., Simon, T., Sitruk-Ware, R., Stevenson, J. & 8 others, Taddei, S., van der Schouw, Y. T., Williams, D. J., Sturdee, D., Collins, P., Genazzani, A., Simoncini, T. & Workshop Consensus Grp, 2009, In : Climacteric. 12, p. 368-377 10 p.

Research output: Contribution to journalArticleScientific

Association between high risk papillomavirus DNA and nitric oxide release in the human uterine cervix

Rahkola, P., Mikkola, T., Ylikorkala, O. & Väisänen-Tommiska, M., 2009, In : Gynecologic Oncology. 114, 2, p. 323-326 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Cardiovascular risk assessment in postmenopausal women: the role of the gynecologist

Mikkola, T., 2009, In : Climacteric. 12, suppl. 1, p. 58-61 4 p.

Research output: Contribution to journalArticleScientificpeer-review

Effect of hot flushes on vascular function: a randomized controlled trial

Tuomikoski, P., Ebert, P., Groop, P. H., Haapalahti, P., Hautamäki, H., Rönnback, M., Ylikorkala, O. & Mikkola, T. S., 2009, In : Obstetrics and Gynecology. 114, 4, p. 777-785 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Evidence for a role of hot flushes in vascular function in recently postmenopausal women

Tuomikoski, P., Ebert, P., Groop, P. H., Haapalahti, P., Hautamäki, H., Rönnback, M., Ylikorkala, O. & Mikkola, T. S., 2009, In : Obstetrics and Gynecology. 113, 4, p. 902-908 7 p.

Research output: Contribution to journalArticleScientificpeer-review

2010

Association between vasomotor hot flashes and heart rate variability in recently postmenopausal women

Hoikkala, H., Haapalahti, P., Viitasalo, M., Väänänen, H., Sovijärvi, A., Ylikorkala, O. & Mikkola, T. S., 2010, In : Menopause. 17, 2, p. 315-320 6 p.

Research output: Contribution to journalArticleScientificpeer-review