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Tommi Kajander

  • PL 65 (Viikinkaari 1)

    00014

    Finland

  • Viikinkaari 5, Biocenter 2

    00790 Helsinki

    Finland

20052020

Research output per year

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Personal profile

Curriculum vitae

Principal Investigator, Senior Scientist (Insititute of Biotechnolgoy) 2011-

Academy Research  Fellow (Insititute of Biotechnolgoy) 2011-2016

Head of Crystallization Core facility (Instruct-HiLIFE) 2013-

Qualifications:

Ph.D. (2003 University of Helsinki, Biochemistry), Title of Docent in Protein chemistry (Uinv. Helsinki)  (2009).

 

Addtional training:

University pedagogics I + III + IV (2009-2016) (20 ECTS).

Leadership Programme for Academic Staff (2013) (5 ECTS).

 

Previous appointments:

Post doctoral fellow  at Yale University 2003-2006

Resaercher, Dept. of Virology, Univ. Helsinki, 2001-2003.

 

Description of research and teaching

Research interests: Structural biology, crystallization, protein-protein interactions, protein engineering and molecular mechanisms, synaptic adhesion, integral membrane proteins.

Teaching: Introduciton to structural biology and biophysics (5 ECTS)

 

Fields of Science

  • 1182 Biochemistry, cell and molecular biology
  • biochemistry
  • structural biology
  • biophysics
  • protein engineering
  • protein chemistry

International and National Collaboration Publications and projects within past five years.

Publications

Structural basis of SALM3 dimerization and synaptic adhesion complex formation with PTPσ

Karki, S., Shkumatov, A. V., Bae, S., Ko, J. & Kajander, T., 9 Jan 2020, In : bioRxiv : the preprint server for biology .

Research output: Contribution to journalOther articlesScientific

Open Access

Structural basis of SALM3 dimerization and synaptic adhesion complex formation with PTPσ

Karki, S., Shkumatov, A. V., Bae, S., Kim, H., Ko, J. & Kajander, T., 14 Jul 2020, In : Scientific Reports. 10 , 11557, https://doi.org/10.1038/s41598-020-68502-4.

Research output: Contribution to journalArticleScientificpeer-review

Inhibitor screening assay for neurexin-LRRTM adhesion protein interaction involved in synaptic maintenance and neurological disorders.

Karki, S., Maksimainen, M. M., Lehtiö, L. & Kajander, T., 15 Dec 2019, In : Analytical Biochemistry. 587, 113463.

Research output: Contribution to journalArticleScientificpeer-review

Structure-based virtual screening of LsrK kinase inhibitors to target quorum sensing

Medarametla, P., Gatta, V., Kajander, T. A., Laitinen, T., Tammela, P. S. M. & Poso, A., 20 Nov 2018, In : ChemMedChem : chemistry enabling drug discovery.. 13, 22, p. 2400-2407 8 p.

Research output: Contribution to journalArticleScientificpeer-review

The structure of SALM5 suggests a dimeric assembly for the presynaptic RPTP ligand recognition.

Karki, S., Paudel, P., Sele, C. P. E., Shkumatov, A. V. & Kajander, T. A., May 2018, In : Protein Engineering, Design and Selection. 31, 5, p. 147-157 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Projects

Jane ja Aatos Erkon säätiö / Tommi Kajander

Kajander, T.

01/06/201531/12/2018

Project: Research project

Hermoston leusiinirikkaiden toistoproteiinien rakennebiologia

Kajander, T.

01/09/201131/08/2016

Project: Research project

Activities

  • 3 Peer review of manuscripts
  • 2 Membership or other role in national/international committee, council, board
  • 1 Membership or other role in public Finnish or international organization
  • 1 Membership or other role in research network

EU COST-action: Movement and Mechanism in Molecular Machines (External organisation)

Tommi Kajander (Member)

20142018

Activity: Membership typesMembership or other role in research network

FSRUO (External organisation)

Tommi Kajander (Board member)

1 Nov 2013 → …

Activity: Membership typesMembership or other role in national/international committee, council, board

Institute of Biotechnology (External organisation)

Tommi Kajander (Board member)

30 Jun 2010 → …

Activity: Membership typesMembership or other role in national/international committee, council, board

Structure (Journal)

Tommi Kajander (Reviewer)

1 Jan 20072017

Activity: Publication peer-review and editorial work typesPeer review of manuscripts

Protein Society, European Crystallographic Association (External organisation)

Tommi Kajander (Member)

1 Jan 200731 Dec 2007

Activity: Membership typesMembership or other role in public Finnish or international organization