Research output per year
Research output per year
Personal profile
Curriculum vitae
Principal Investigator, Senior Scientist (Insititute of Biotechnolgoy) 2011-
Academy Research Fellow (Insititute of Biotechnolgoy) 2011-2016
Head of Crystallization Core facility (Instruct-HiLIFE) 2013-
Qualifications:
Ph.D. (2003 University of Helsinki, Biochemistry), Title of Docent in Protein chemistry (Uinv. Helsinki) (2009).
Addtional training:
University pedagogics I + III + IV (2009-2016) (20 ECTS).
Leadership Programme for Academic Staff (2013) (5 ECTS).
Previous appointments:
Post doctoral fellow at Yale University 2003-2006
Resaercher, Dept. of Virology, Univ. Helsinki, 2001-2003.
Description of research and teaching
Research interests: Structural biology, crystallization, protein-protein interactions, protein engineering and molecular mechanisms, synaptic adhesion, integral membrane proteins.
Teaching: Introduciton to structural biology and biophysics (5 ECTS)
Fields of Science
- 1182 Biochemistry, cell and molecular biology
- biochemistry
- structural biology
- biophysics
- protein engineering
- protein chemistry
International and National Collaboration
Publications and projects within past five years.
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Membrane remodeling by FAM92A1 during brain development regulates neuronal morphology, synaptic function, and cognition
Wang, L., Yang, Z., Fudo, S., Anthony Raj, X. P., Yan, Z., Vihinen, H., Chen, Y., Zhao, Y., He, X., Bu, Q., Li, H., Zhao, Y., Jiang, L., Qin, F., Dai, Y., Zhang, N., Qin, M., Kuang, W., Zhao, Y., Jokitalo, E., & 4 others, 2024, In: Nature Communications. 15, 1, 30 p., 6209.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Reduced binding of apoE4 to complement factor H promotes amyloid-beta oligomerization and neuroinflammation
Chernyaeva, L., Ratti, G., Teirilä, L., Fudo, S., Rankka, U., Pelkonen, A., Korhonen, P., Leskinen, K., Keskitalo, S., Salokas, K., Gkolfinopoulou, C., Crompton, K. E., Javanainen, M., Happonen, L., Varjosalo, M., Malm, T., Leinonen, V., Chroni, A., Saavalainen, P., Meri, S., & 4 others, 5 Jul 2023, In: EMBO Reports. 24, 7, 23 p., e56467.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Stereospecific Synthesis of Cyclohexenone Acids by [3,3]-Sigmatropic Rearrangement Route
Eronen, A., Nieger, M., Kajander, T. A. & Repo, T., Sept 2023, In: Journal of Organic Chemistry. 88, 18, p. 12914-12923 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
MDGA1 negatively regulates amyloid precursor protein-mediated synapse inhibition in the hippocampus
Kim, J., Kim, S., Kim, H., Hwang, I-W., Bae, S., Karki, S., Kim, D., Ogelman, R., Bang, G., Kim, J. Y., Kajander, T., Um, J. W., Oh, W. C. & Ko, J., 25 Jan 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 4, 11 p., 2115326119.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Crystallization and low-resolution structure solution of the SALM3–PTPσ synaptic adhesion complex
Karki, S. & Kajander, T., 2021, In: Acta crystallographica section f-Structural biology communications. F78, p. 39-44Research output: Contribution to journal › Article › Scientific › peer-review
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Jane_Aatos Erkon säätiö_Haapasalo 24-25
Haapasalo, K., Kajander, T. & Uvarov, P.
01/09/2024 → 31/08/2026
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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Integrated Structural Biology Infrastructure-European Research Infrastructure Consortium (Instruct-ERIC) / Consortium FINStruct and Instruct-ERIC
Butcher, S., Poranen, M., Varjosalo, M., Kajander, T., Oksanen, H. M., Eskelin , K., Lehtiö, L., Salminen, T. A. & Papageorgiou, A. C.
01/01/2022 → 31/12/2026
Project: Research Council of Finland: Research infrastructure
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Structural Biology Finland (FINStruct) & Instruct-ERIC Centre FI / Research Infrastructure Roadmap 2021-2024
Butcher, S., Poranen, M., Kajander, T., Iwai, H., Varjosalo, M., Lehtiö, L., Rouvinen, J., Salminen, T. A., Papageorgiou, A. C., Oksanen, H. M. & Eskelin , K.
01/01/2021 → 31/12/2024
Project: Research Council of Finland: Research infrastructure
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Integrated Structural Biology Infrastructure / Consortium: Instruct-Suomi
Butcher, S., Kajander, T., Lehtiö, L., Määttä, J. A. E., Papageorgiou, A., Rouvinen, J., Salminen, T., Iwai, H., Poranen, M., Eskelin , K. & Oksanen, H. M.
01/01/2020 → 31/12/2022
Project: Other project
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Activities
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Calsyntenin-3 Laminin G-Like Domain Forms Dimers in a Solution
Tommi Kajander (Supervisor)
27 Jan 2021Activity: Examination types › Supervision of other thesis (Master's, Licentiate)
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Instruct-ERIC Centre Finland Opening and Structural Biology Finland Conference 2021
Tommi Kajander (Member of organizing committee)
17 Dec 2021Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Frontiers in Molecular Biosciences (Journal)
Tommi Kajander (Member of editorial board)
1 Jun 2021 → …Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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The Finnish Annual Structural Biology meeting FINNBOX 2019
Tommi Kajander (Chair of organizing committee)
3 Sept 2019Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Expression and characterization of neuronal membrane receptor proteins
Tommi Kajander (Supervisor)
16 Dec 2016Activity: Examination types › Supervisor or co-supervisor of doctoral thesis
Equipment
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Instruct-HILIFE protein crystallography platform
Tommi Kajander (Manager)
Institute of BiotechnologyFacility/equipment: Core Facility
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Structural Biology Finland (FINStruct)
Sarah Butcher (Manager), Hanna M Oksanen (Other), Minna Poranen (Other), Katri Eskelin (Other), Tommi Kajander (Other), Perttu Permi (Other), Lari Lehtiö (Other), Juha Rouvinen (Other), Tiina A Salminen (Other) & Anastassios Papageorgiou (Other)
Faculty of Biological and Environmental SciencesFacility/equipment: Core Facility