Photo of Topi Tervonen
  • PL 63 (Haartmaninkatu 8)

    00014

    Finland

20052018
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Personal profile

Education/Academic qualification

PhD, Neuroscience Center

1 Sep 20032 Apr 2008

MSc, University of Eastern Finland (UEF)

9 Sep 199613 Aug 2003

Keywords

  • 3111 Biomedicine
  • 318 Medical biotechnology
  • 1182 Biochemistry, cell and molecular biology
  • 3122 Cancers

International and National Collaboration Publications and projects within past five years.

Publications 2005 2018

Analyzing the Type II Transmembrane Serine Protease Hepsin-Dependent Basement Membrane Remodeling in 3D Cell Culture

Pant, S. M., Belitskin, D., Ala-Hongisto, H., Klefström, J. & Tervonen, T. A., 2018, PROTEASES AND CANCER: METHODS AND PROTOCOLS . Cal, S. & Obaya, A. J. (eds.). TOTOWA, NJ : Humana Press Inc., p. 169-178 10 p. (Methods in Molecular Biology ; vol. 1731).

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform

Pant, S. M., Mukonoweshuro, A., Desai, B., Ramjee, M. K., Selway, C. N., Tarver, G. J., Wright, A. G., Birchall, K., Chapman, T. M., Tervonen, T. A. & Klefström, J., 24 May 2018, In : Journal of Medicinal Chemistry. 61, 10, p. 4335-4347 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion

Tervonen, T. A., Belitskin, D., Pant, S. M., Englund, J. I., Marques, E., Ala-Hongisto, H., Nevalaita, L., Sihto, H., Heikkila, P., Leidenius, M., Hewitson, K., Ramachandra, M., Moilanen, A., Joensuu, H., Kovanen, P. E., Poso, A. & Klefstrom, J., 7 Apr 2016, In : Oncogene. 35, 14, p. 1832-1846 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Par6G suppresses cell proliferation and is targeted by loss-of-function mutations in multiple cancers

Marques, E., Englund, J. I., Tervonen, T. A., Virkunen, E., Laakso, M., Myllynen, M., Mäkelä, A., Ahvenainen, M., Lepikhova, T., Monni, O., Hautaniemi, S. & Klefstrom, J., 17 Mar 2016, In : Oncogene. 35, 11, p. 1386-1398 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

CRISPR/Cas9 system for versatile genome editing

Tervonen, T. A., 2015

Research output: Non-textual formDigital or Visual ProductsScientific

Activities 2009 2015

  • 8 Organisation and participation in conferences, workshops, courses, seminars
  • 3 Supervision of other thesis (Master's, Licentiate)
  • 2 Supervisor or co-supervisor of doctoral thesis
  • 1 Membership or other role in research network

Advanced molecular biology techniques 51070

Topi Tervonen (Speaker: Presenter)
Jan 2015

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Small molecular inhibitors of hepsin in breast cancer

Topi Tervonen (Co-supervisor)
2015 → …

Activity: Examination typesSupervisor or co-supervisor of doctoral thesis

EMEA CRISPR Core Directors Meeting 2015

Topi Tervonen (Attendee)
May 2015

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Pre-Symposium Event for Translational Cancer Biology Symposium 2015

Topi Tervonen (Member of organizing committee)
Aug 2015

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Advanced molecular biology techniques 51070

Topi Tervonen (Speaker: Presenter)
Jan 2015

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars