Research Output per year
Personal profile
Education/Academic qualification
PhD, Neuroscience Center
1 Sep 2003 → 2 Apr 2008
MSc, University of Eastern Finland (UEF)
9 Sep 1996 → 13 Aug 2003
Fields of Science
- 3111 Biomedicine
- 318 Medical biotechnology
- 1182 Biochemistry, cell and molecular biology
- 3122 Cancers
International and National Collaboration
Publications and projects within past five years.
Publications
Analyzing the Type II Transmembrane Serine Protease Hepsin-Dependent Basement Membrane Remodeling in 3D Cell Culture
Pant, S. M., Belitskin, D., Ala-Hongisto, H., Klefström, J. & Tervonen, T. A., 2018, PROTEASES AND CANCER: METHODS AND PROTOCOLS . Cal, S. & Obaya, A. J. (eds.). TOTOWA, NJ : Humana press, p. 169-178 10 p. (Methods in Molecular Biology ; vol. 1731).Research output: Chapter in Book/Report/Conference proceeding › Chapter › Scientific › peer-review
Design, Synthesis, and Testing of Potent, Selective Hepsin Inhibitors via Application of an Automated Closed-Loop Optimization Platform
Pant, S. M., Mukonoweshuro, A., Desai, B., Ramjee, M. K., Selway, C. N., Tarver, G. J., Wright, A. G., Birchall, K., Chapman, T. M., Tervonen, T. A. & Klefström, J., 24 May 2018, In : Journal of Medicinal Chemistry. 61, 10, p. 4335-4347 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion
Tervonen, T. A., Belitskin, D., Pant, S. M., Englund, J. I., Marques, E., Ala-Hongisto, H., Nevalaita, L., Sihto, H., Heikkila, P., Leidenius, M., Hewitson, K., Ramachandra, M., Moilanen, A., Joensuu, H., Kovanen, P. E., Poso, A. & Klefstrom, J., 7 Apr 2016, In : Oncogene. 35, 14, p. 1832-1846 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
Par6G suppresses cell proliferation and is targeted by loss-of-function mutations in multiple cancers
Marques, E., Englund, J. I., Tervonen, T. A., Virkunen, E., Laakso, M., Myllynen, M., Mäkelä, A., Ahvenainen, M., Lepikhova, T., Monni, O., Hautaniemi, S. & Klefstrom, J., 17 Mar 2016, In : Oncogene. 35, 11, p. 1386-1398 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
CRISPR/Cas9 system for versatile genome editing
Tervonen, T. A., 2015Research output: Non-textual form › Digital or Visual Products › Scientific
Prizes
Travel grant of the Chancellor of University of Helsinki 2012: 1200 € (Mechanism & Models of Cancer 2012, Cold Spring Harbor Lab, NY, USA)
Topi Tervonen (Recipient), 2012
Prize: Prizes and awards
Activities
Advanced molecular biology techniques 51070
Topi Tervonen (Speaker: Presenter)Jan 2015
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Advanced molecular biology techniques 51070
Topi Tervonen (Speaker: Presenter)Jan 2015
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Small molecular inhibitors of hepsin in breast cancer
Topi Tervonen (Co-supervisor)2015 → …
Activity: Examination types › Supervisor or co-supervisor of doctoral thesis
Viral Gene Transfer and Cell Therapy Technology Platform (VGTCT), Biocenter Finland (External organisation)
Topi Tervonen (Member)Nov 2015 → …
Activity: Membership types › Membership or other role in research network
Pre-Symposium Event for Translational Cancer Biology Symposium 2015
Topi Tervonen (Member of organizing committee)Aug 2015
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars