Research output per year
Research output per year
Publications
- 6 Article
Search results
-
2024
Freeze-drying-induced mutarotation of lactose detected by Raman spectroscopy
Monola, J., Koivunotko, E., Zini, J., Niemelä, A., Koivuniemi, A., Kröger, A., Korhonen, O., Valkonen, S., Merivaara, A., Harjumäki, R., Yliperttula, M. & Kekkonen, J., Dec 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 205, 12 p., 114534.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Gliflozins, sucrose and flavonoids are allosteric activators of lecithin-cholesterol acyltransferase
Niemelä, A., Giorgi, L., Nouri, S., Yurttaş, B., Rauniyar, K., Jeltsch, M. & Koivuniemi, A., Dec 2024, In: Scientific Reports. 14, 1, 26085.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Systematic evaluation of lecithin:Cholesterol acyltransferase binding sites in apolipoproteins via peptide based nanodiscs: Regulatory role of charged residues at positions 4 and 7
Niemelä, A. & Koivuniemi, A., 28 May 2024, In: PLoS Computational Biology. 20, 5, 22 p., e1012137.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2022
Mechanistic Insights into the Activation of Lecithin-Cholesterol Acyltransferase in Therapeutic Nanodiscs Composed of Apolipoprotein A-I Mimetic Peptides and Phospholipids
Giorgi, L., Niemelä, A., Kumpula, E.-P., Natri, O., Parkkila, P., Huiskonen, J. T. & Koivuniemi, A., 7 Nov 2022, In: Molecular Pharmaceutics. 19, 11, p. 4135-4148 14 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
2021
Molecular Insights on Successful Reconstitution of Freeze-Dried Nanofibrillated Cellulose Hydrogel
Koivunotko, E., Merivaara, A., Niemela, A., Valkonen, S., Manninen, K., Makinen, H., Viljanen, M., Svedstrom, K., Diaz, A., Holler, M., Zini, J., Paasonen, L., Korhonen, O., Huotari, S., Koivuniemi, A. & Yliperttula, M., 20 Sept 2021, In: ACS Applied Bio Materials. 4, 9, p. 7157-7167 11 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Positive allosteric modulators of lecithin: Cholesterol acyltransferase adjust the orientation of the membrane-binding domain and alter its spatial free energy profile
Niemela, A. & Koivuniemi, A., Mar 2021, In: PLoS Computational Biology. 17, 3, 16 p., 1008426.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile