Research output per year
Research output per year
Personal profile
Education/Academic qualification
Farmasian tohtori
Award Date: 22 Jun 2021
Proviisori
Award Date: 20 May 2016
Fields of Science
- 317 Pharmacy
International and National Collaboration
Publications and projects within past five years.
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New SCN5A mutation P1891A causes left ventricular noncompaction and links Nav1.5 protein-protein interactions to cardiomyocyte proliferation and tissue compaction
Majid, Q., Prajapati, C., Liu, X., Kari-Koskinen, J., Karhu, T., Ruskoaho, H., E. Harding, S., Varjosalo, M., Aalto-Setälä, K. & Talman, V., 2024, (In preparation) In: Circulation Research.Research output: Contribution to journal › Article › Scientific › peer-review
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Expanding the Paradigm of Structure-Based Drug Design: Molecular Dynamics Simulations Support the Development of New Pyridine-Based Protein Kinase C–Targeted Agonists
Lautala, S., Provenzani, R., Tarvainen, I., Sirna, K., Karhu, T., Grazhdankin, E., Lehtinen, A. K., S'ad, H., Koivuniemi, A., Xhaard, H., Tuominen, R. K., Talman, V., Bunker, A. E. & Yli-Kauhaluoma, J., 13 Apr 2023, In: Journal of Medicinal Chemistry. 66, 7, p. 4588-4602 15 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
In vitro Evaluation of the Therapeutic Effects of Dual-Drug Loaded Spermine-Acetalated Dextran Nanoparticles Coated with Tannic Acid for Cardiac Applications
Torrieri, G., Almeida Ferreira, M., Shahbazi, M-A., Talman, V., Karhu, T., Pohjolainen, L., Carvalho, C., Pinto, J. F., Hirvonen, J., Ruskoaho, H., Balasubramanian, V. & Santos, H. A., 26 Jan 2022, In: Advanced Functional Materials. 32, 5, 16 p., 2109032.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Distinct Regulation of Cardiac Fibroblast Proliferation and Transdifferentiation by Classical and Novel Protein Kinase C Isoforms: Possible Implications for New Antifibrotic Therapies
Karhu, S. T., Ruskoaho, H. & Talman, V., 1 Feb 2021, In: Molecular pharmacology : an international journal. 99, 2, p. 104-113 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Pharmacological and toxicological characterisation of GATA4- and protein kinase C-targeted compounds in cardiac cell models
Karhu, T., 2021, Helsinki: Helsingin yliopisto.Research output: Thesis › Doctoral Thesis › Collection of Articles
Open Access
Projects
- 1 Finished
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Protein kinase C as a drug target in cardiac remodelling and regeneration
Talman, V., Karhu, T. & Pohjolainen, L.
01/06/2016 → 31/12/2020
Project: Research project
Prizes
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2019 Paul Dudley White International Scholar Award
Karhu, Tuuli (Recipient), 30 Jul 2019
Prize: Prizes and awards
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The Most Outstanding Pharmaceutical Research Article Award 2022
Talman, Virpi (Recipient), Ruskoaho, Heikki (Recipient) & Karhu, Tuuli (Recipient), 10 Nov 2022
Prize: Prizes and awards
Activities
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Lapsiasiakas apteekissa - Täit ja kihomadot
Tuuli Karhu (Speaker)
2 Oct 2020Activity: Talk or presentation types › Invited talk
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Basic Cardiovascular Sciences Scientific Sessions 2019
Tuuli Karhu (Attendee)
29 Jul 2019 → 1 Aug 2019Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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WCP2018, 18th World Congress of Basic and Clinical Pharmacology
Tuuli Karhu (Attendee)
1 Jul 2018 → 6 Jul 2018Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Frontiers in Cardiovascular Biology
Tuuli Karhu (Attendee)
20 Apr 2018 → 22 Apr 2018Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars