Research Output per year
Personal profile
Curriculum vitae
ORCID: 0000-0001-6169-5035
EDUCATION AND DEGREES AWARDED
**Fellow of the Higher Education Academy, UK (FHEA), 2018
**”Title of Docent” (Dosentii) in Pharmaceutical Chemistry, University of Helsinki, Finland, 2015
**Ph.D. in Pharmaceutical Organic Chemistry, University of Coimbra, Portugal & University of Maryland, USA, (highest-scoring grade, “Passed with Distinction and Honours”), 2008
**Degree in Pharmaceutical Sciences (Pharm.D.), University of Coimbra, Portugal, Grade 17 out of 20 (First-class honours), awarded with the “ Sociedade Farmacêutica Lusitana Award” (best student of Pharmaceutical Sciences of the year in Portugal), 2003
RESEARCH AREAS
Drug Discovery, Medicinal Chemistry, Natural Products, Antimicrobial and anti-biofilm agents & materials, Neglected diseases, Cancer, (Neuro)inflammation
MAJOR FUNDING SOURCES
The Finnish Funding Agency for Innovation (TEKES); Huonekalusäätio; University of Helsinki Research Funds; Magnus Ehrnrooth Foundation; Portuguese Science and Technology Foundation (FCT); FP7-HEALTH-2013-INNOVATION-1 (European Funding); Academy of Finland; Tenovus Scotland
CURRENT COMPOSITION OF RESEARCH GROUP
Doctoral students
*Declan Mullen - Next generation bio-based antimicrobial agents, University of Strathclyde, UK
*Ghada Hassan - Sustainable antimicrobial coatings, University of Helsinki, FI
*Tiina Ahonen - New drugs for chronic pain, University of Helsinki, FI
FORMER RESEARCH GROUP MEMBERS
Post-doctoral researchers
**Dr. Xing Wan, University of Helsinki, FI
**Dr. Leena Keurulainen, University of Helsinki, FI
Doctoral students
*Dr. Nina Forsman - Sustainable multifunctional coatings for textiles and other cellulosic materials (grad. 2020)
*Dr. Laura E. Kolsi - Synthesis of abietane-type diterpenoids with anticancer activity (grad. 2019)
*Dr. Raisa Haavikko - Synthesis of betulins with new bioactivities (grad. 2015)
*Dr. Nehad El-Salamouni - Design and synthesis of some novel phenolic compounds and their quinone oxidation products of potential biological activities (grad. 2013)
Fields of Science
- 317 Pharmacy
- Pharmaceutical Chemistry
- Medicinal Chemistry
- Drug repositioning
- Natural Products
- 116 Chemical sciences
- Organic Chemistry
- Steroids
- Terpenes
- Catalysis
- Oxidations
International and National Collaboration
Publications and projects within past five years.
Publications
Regioselective Benzylic Oxidation of Aromatic Abietanes: Application to the Semisynthesis of the Naturally Occurring Picealactones A, B and C
Kolsi, L. E., Krogerus, S., Brito, V., Rüffer, T., Lang, H., Yli-Kauhaluoma, J. T., Silvestre, S. & Moreira, V. M., 22 Aug 2017, In : ChemistrySelect. 2, 24, p. 7008-7012 5 p.Research output: Contribution to journal › Article › Scientific › peer-review
Antiprotozoal activity of dehydroabietic acid derivatives against Leishmania donovani and Trypanosoma cruzi - SPECIAL ISSUE "NEW TALENT: EUROPE"
Vahermo, M., Krogerus, S., Nasereddin, A., Kaiser, M., Brun, R., Jaffe, C. L., Yli-Kauhaluoma, J. & Moreira, V. M., 2016, In : MedChemComm. 7, 3, p. 457-463 7 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access
File
New derivatives of dehydroabietic acid target planktonic and biofilm bacteria in Staphylococcus aureus and effectively disrupt bacterial membrane integrity
Manner, S., Vahermo, M., Skogman, M., Krogerus, S., Vuorela, P. M., Yli-Kauhaluoma, J., Fallarero, A. & Moreira, V. M., 21 Jul 2015, In : European Journal of Medicinal Chemistry. 102, p. 68-79 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
Drug repositioning: a machine-learning approach through data integration
Napolitano, F., Zhao, Y., Moreira, V. M., Tagliaferri, R., Kere, J., D'Amato, M. & Greco, D., 22 Jun 2013, In : Journal of Cheminformatics. 5, Article Number: 30 , 9 p.Research output: Contribution to journal › Article › Scientific › peer-review
Bismuth(III) Triflate-Based Catalytic Direct Opening of Oleanolic Hydroxy-gamma-lactones to Afford 12-Oxo-28-carboxylic Acids
Salvador, J. A. R., Moreira, V. M., Pinto, R. M. A., Leal, A. S. & Le Roux, C., 10 Oct 2011, In : Advanced Synthesis & Catalysis. 353, p. 2637-2642Research output: Contribution to journal › Article › Scientific › peer-review
Projects
EC-FP7-HEALTH-2013-INNOVATION-1: Understanding chronic pain and new druggable targets: Focus on glial-opioid receptor interface (GLORIA)
Kalso, E., Yli-Kauhaluoma, J., Moreira, V. M., Saarma, M., Xhaard, H., Airavaara, M., Sidorova, Y., Rauhala, P., Kambur, O., Karhinen, L. & Ahonen, T.
01/11/2013 → 31/10/2018
Project: Research project
Synthesis of Oxamniquine Derivatives for Cancer Treatment. A Drug Repositioning Approach.
Krogerus, S., Bimbo, L. M., Greco, D., Yli-Kauhaluoma, J. & Moreira, V. M.
01/03/2013 → 28/02/2014
Project: Research project
Prizes
Post-doctoral Fellowship (SFRH/BPD/45037/2008)
Vânia M. Moreira (Recipient), 2009
Prize: Prizes and awards
Semi-finalist team in OneStart Competition: GFL mimetics, Helsinki
Vânia M. Moreira (Recipient), 5 Mar 2013
Prize: Prizes and awards
Sociedade Farmacêutica Lusitana Award (best student of Pharmaceutical Sciences of the year)
Vânia M. Moreira (Recipient), Apr 2003
Prize: Prizes and awards
Activities
COST Action CM1307, “Targeted chemotherapy towards diseases caused by endoparasites“ (External organisation)
Vânia M. Moreira (Member)Jan 2016
Activity: Membership types › Membership or other role in national/international committee, council, board
Member of the International Scientific Advisory Committee of the XXIV EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC)
Vânia M. Moreira (Scientific Committee Member)Aug 2016 → Sep 2016
Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Invited talk, International Caparica Christmas Congress on Translational Chemistry
Vânia M. Moreira (Speaker)Dec 2017
Activity: Talk or presentation types › Invited talk
University of Strathclyde
Vânia M. Moreira (Visiting researcher)May 2017 → Aug 2017
Activity: Visiting an external institution types › Academic visit to other institution
New diterpenoids for chronic pain treatment
Vânia M. Moreira (Supervisor)Jan 2016
Activity: Examination types › Supervision of other thesis (Master's, Licentiate)
Press / Media
HY news: Tutkijat kaivautuvat kivun juurille
10/12/2013
1 Media contribution
Press/Media: Press / Media