Research output per year
Research output per year
Personal profile
Fields of Science
- 3111 Biomedicine
International and National Collaboration
Publications and projects within past five years.
Publications
- 11 Article
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The oncolytic adenovirus TILT-123 with pembrolizumab in platinum resistant or refractory ovarian cancer: the phase 1a PROTA trial
Block, M. S., Clubb, J. H. A., Mäenpää, J., Pakola, S., Quixabeira, D. C. A., Kudling, T., Jirovec, E., Haybout, L., van der Heijden, M., Zahraoui, S., Grönberg-Vähä-Koskela, S., Raatikainen, S., Arias, V., Basnet, S., Ojala, N., Pellinen, T., Hemmes, A., Välimäki, K., Pasanen, A. & Alanko, T. & 14 others, , 5 Feb 2025, In: Nature Communications. 16, 1, 14 p., 1381.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Transient lymphocyte count decrease correlates with oncolytic adenovirus efficacy in humans: mechanistic and biomarker findings from TUNIMO phase I trial
Pakola, S. A., Clubb, J. H. A., Kudling, T., van der Heijden, M., Jirovec, E., Arias, V., Haybout, L., Peltola, K., Alanko, T., Sormunen, J., Pellinen, T., Taipale, K., Quixabeira, D. C. A., Kistler, C., Havunen, R., Sorsa, S., Santos, J. M., Cervera-Carrascon, V. & Hemminki, A., 27 Jan 2025, In: Journal for ImmunoTherapy of Cancer. 13, 1, 15 p., e010493.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Overcoming effector T cell exhaustion in ovarian cancer ascites with a novel adenovirus encoding for a MUC1 bispecific antibody engager and IL-2 cytokine
Basnet, S., Van der Heijden, M., Quixabeira, D. C. A., Jirovec, E., Grönberg-Vähä-Koskela, S. A. M., Clubb, J. H. A., Kanerva, A., Pakola, S., Haybout, L., Arias, V., Hemminki, O., Kudling, T., Zafar, S., Santos, J. M. & Hemminki, A., 2024, In: Molecular therapy. 32, 9, p. 3114-3127 14 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Single intravenous administration of oncolytic adenovirus TILT-123 results in systemic tumor transduction and immune response in patients with advanced solid tumors
Jirovec, E., Quixabeira, D. C. A., Clubb, J. H. A., Pakola, S. A., Kudling, T., Arias, V., Haybout, L., Jalkanen, K., Alanko, T., Monberg, T., Khammari, A., Dreno, B., Svane, I. M., Block, M. S., Adamo, D. A., Mäenpää, J., Kistler, C., Sorsa, S., Hemminki, O. & Kanerva, A. & 3 others, , Dec 2024, In: Journal of Experimental and Clinical Cancer Research. 43, 1, 15 p., 297.Research output: Contribution to journal › Article › Scientific › peer-review
Open Access -
An oncolytic adenovirus coding for a variant interleukin 2 cytokine improves response to chemotherapy through enhancement of effector lymphocyte cytotoxicity, fibroblast compartment modulation and mitotic slippage
Pakola, S., Quixabeira, D. C. A., Kudling, T. V., Clubb, J. H. A., Grönberg-Vähä-Koskela, S., Basnet, S., Jirovec, E., Arias, V., Haybout, L., Heiniö, C., Santos, J. M., Cervera-Carrascon, V., Havunen, R., Anttila, M. & Hemminki, A., 5 Jul 2023, In: Frontiers in Immunology. 14, 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile
Projects
- 1 Active
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Veripalvelu 2023-25 A. Hemminki
Hemminki, A. (Project manager) & Arias Illana, V. (Participant)
SUOMEN PUNAINEN RISTI, VERIPALVELU
01/01/2023 → 31/12/2025
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)