Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells

Balboa, D., Barsby, T., Lithovius, V., Saarimaki-Vire, J., Omar-Hmeadi, M., Dyachok, O., Montaser, H., Lund, P-E., Yang, M., Ibrahim, H., Näätänen, A., Chandra, V., Vihinen, H., Jokitalo, E., Kvist, J., Ustinov, J., Nieminen, A., Kuuluvainen, E., Hietakangas, V., Katajisto, P. & 5 others, Lau, J., Carlsson, P-O., Barg, S., Tengholm, A. & Otonkoski, T., 3 Mar 2022, (E-pub ahead of print) In: Nature Biotechnology. 21 p.

Research output: Contribution to journal › Article › Scientific › peer-review

Loss of MANF Causes Childhood-Onset Syndromic Diabetes Due to Increased Endoplasmic Reticulum Stress

Montaser, H., Patel, K. A., Balboa, D., Ibrahim, H., Lithovius, V., Näätänen, A., Chandra, V., Demir, K., Acar, S., Ben-Omran, T., Colclough, K., Locke, J. M., Wakeling, M., Lindahl, M., Hattersley, A. T., Saarimaki-Vire, J. & Otonkoski, T., Apr 2021, In: Diabetes. 70, 4, p. 1006-1018 13 p.

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Early Detection of Peripheral Blood Cell Signature in Children Developing beta-Cell Autoimmunity at a Young Age

Kallionpää, H., Somani, J., Tuomela, S., Ullah, U., de Albuquerque, R., Lönnberg, T., Komsi, E., Siljander, H., Honkanen, J., Härkönen, T., Peet, A., Tillmann, V., Chandra, V., Anagandula, M. K., Frisk, G., Otonkoski, T., Rasool, O., Lund, R., Lähdesmäki, H., Knip, M. & 1 others, Lahesmaa, R., Oct 2019, In: Diabetes. 68, 10, p. 2024-2034 11 p.

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Loss of ZnT8 function protects against diabetes by enhanced insulin secretion

Dwivedi, O. P., Lehtovirta, M., Hastoy, B., Chandra, V., Krentz, N. A. J., Kleiner, S., Jain, D., Richard, A-M., Abaitua, F., Beer, N. L., Grotz, A., Prasad, R. B., Hansson, O., Ahlqvist, E., Krus, U., Artner, I., Suoranta, A., Gomez, D., Baras, A., Champon, B. & 27 others, Payne, A. J., Moralli, D., Thomsen, S. K., Kramer, P., Spiliotis, I., Ramracheya, R., Chabosseau, P., Theodoulou, A., Cheung, R., van de Bunt, M., Flannick, J., Trombetta, M., Bonora, E., Wolheim, C. B., Sarelin, L., Bonadonna, R. C., Rorsman, P., Davies, B., Brosnan, J., McCarthy, M., Otonkoski, T., Lagerstedt, J. O., Rutter, G. A., Gromada, J., Gloyn, A. L., Tuomi, T. & Groop, L., Nov 2019, In: Nature Genetics. 51, 11, p. 1596-+ 22 p.

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MANF protects human pancreatic beta cells against stress-induced cell death

Hakonen, E., Chandra, V., Fogarty, C. L., Yu, N. Y-L., Ustinov, J., Katayama, S., Galli, E., Danilova, T., Lindholm, P., Vartiainen, A., Einarsdottir, E., Krjutskov, K., Kere, J., Saarma, M., Lindahl, M. & Otonkoski, T., Oct 2018, In: Diabetologia. 61, 10, p. 2202-2214 13 p.

Research output: Contribution to journal › Article › Scientific › peer-review