Vivek Sharma

  • PL 68 (Pietari Kalmin katu 5)

    00014

    Finland

20062020

Research output per year

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Personal profile

External positions

Academy postdoctoral researcher, Tampere University of Technology

1 Jan 201331 Aug 2016

Fields of Science

  • 1182 Biochemistry, cell and molecular biology
  • Computational biology
  • Computational Chemistry
  • Computational drug design
  • 119 Other natural sciences
  • Molecular dynamics simulations
  • Quantum Chemistry
  • Hybrid QM/MM MD simulations
  • Mitochondrial proteins
  • Redox coupled proton pumping
  • Mitochondrial dysfunction

International and National Collaboration Publications and projects within past five years.

Publications

An Unusual Amino Acid Substitution Within Hummingbird Cytochrome c Oxidase Alters a Key Proton-Conducting Channel

Dunn, C., Akpinar, A. & Sharma, V., 1 Jul 2020, In : G3 - Genes genomes genetics. 10, 7, p. 2477-2485 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

A spontaneous mitonuclear epistasis converging on Rieske Fe-S protein exacerbates complex III deficiency in mice

Purhonen, J., Grigorjev, V., Ekiert, R., Aho, N., Rajendran, J., Pietras, R., Truve, K., Wikström, M., Sharma, V., Osyczka, A., Fellman, V. & Kallijärvi, J., 16 Jan 2020, In : Nature Communications. 11, 1, 12 p., 322.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Coupling of quinone dynamics to proton pumping in respiratory complex I

Haapanen, O., Reidelbach, M. & Sharma, V., 1 Dec 2020, In : Biochimica et Biophysica Acta. Bioenergetics. 1861, 12, 6 p., 148287.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations

Wilmes, S., Hafer, M., Vuorio, J., Tucker, J. A., Winkelmann, H., Loechte, S., Stanly, T. A., Prieto, K. D. P., Poojari, C., Sharma, V., Richter, C. P., Kurre, R., Hubbard, S. R., Garcia, K. C., Moraga, I., Vattulainen, I., Hitchcock, I. S. & Piehler, J., 7 Feb 2020, In : Science. 367, 6478, p. 643-+ 58 p.

Research output: Contribution to journalArticleScientificpeer-review

Oversized ubiquinones as molecular probes for structural dynamics of the ubiquinone reaction site in mitochondrial respiratory complex I

Uno, S., Masuya, T., Shinzawa-Itoh, K., Lasham, J., Haapanen, O., Shiba, T., Inaoka, D. K., Sharma, V., Murai, M. & Miyoshi, H., 21 Feb 2020, In : Journal of Biological Chemistry. 295, 8, p. 2449-2463 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Projects

Molecular mechanisms of mitochondrial enzymes, and their role in health and diseases

Sharma, V., Djurabekova, A., Haapanen, O., Malkamäki, A., Lasham, J., Reidelbach, M. & Chiarini, V.

Project: University of Helsinki Three-Year Research Project

Activities

Chem (Journal)

Vivek Sharma (Reviewer)

2019

Activity: Publication peer-review and editorial work typesPeer review of manuscripts

Modeling of biological systems

Vivek Sharma (Participant)

2019

Activity: Other activity typesTypes for other activities - External teaching and subject coordination

Jagiellonian University

Vivek Sharma (Visiting researcher)

2019

Activity: Visiting an external institution typesAcademic visit to other institution

85th Harden Conference: Dynamic Membrane Complexes: Respiration and Transport

Vivek Sharma (Attendee)

2019

Activity: Participating in or organising an event typesOrganisation and participation in conferences, workshops, courses, seminars

Journal of the American Chemical Society (Journal)

Vivek Sharma (Reviewer)

2019

Activity: Publication peer-review and editorial work typesPeer review of manuscripts