Research output per year
Research output per year
Personal profile
Research interests
My research focuses on the function-structure correlations of virus replication and assembly. I am using the dsRNA virus model system of bacteriophage phi6 to demonstrate the virus assembly process through its life cycle (e.g. to build up virus particles in the test tube step-by-step). I am also interested in the virus infection process and virus-host interaction.
Fields of Science
- 1183 Plant biology, microbiology, virology
- 1182 Biochemistry, cell and molecular biology
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Multiple liquid crystalline geometries of highly compacted nucleic acid in a dsRNA virus
Ilca, S., Sun, X., El Omari, K., Kotecha, A., Haas, F. D., DiMaio, F., Grimes, J. M., Stuart, D. I., Poranen, M. M. & Huiskonen, J. T., 13 Jun 2019, In: Nature. 570, p. 252-+Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Dual Role of a Viral Polymerase in Viral Genome Replication and Particle Self-Assembly
Sun, X., Ilca, S. L., Huiskonen, J. T. & Poranen, M. M., 2018, In: mBio. 9, 5, 14 p., ARTN e01242-18.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Double-stranded RNA virus outer shell assembly by bona fide domain-swapping
Sun, Z., El Omari, K., Sun, X., Ilca, S., Kotecha, A., Stuart, D., Poranen, M. M. & Huiskonen, J. T., Mar 2017, In: Nature Communications. 8, p. 14814Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Localized reconstruction of subunits from electron cryomicroscopy images of macromolecular complexes
Ilca, S. L., Kotecha, A., Sun, X., Poranen, M. M., Stuart, D. I. & Huiskonen, J. T., 4 Nov 2015, In: Nature Communications. 6, 8 p., 8843.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Structure of the bacteriophage phi6 nucleocapsid solved to 3.9 angstrom resolution using electron cryomicroscopy
Sun, Z., Sun, X., Ilca, S., De Colibus, L., Stuart, D. I., Poranen, M. M. & Huiskonen, J. T., Jul 2015, In: The FEBS Journal. 282, S1, p. 51-52 2 p.Research output: Contribution to journal › Meeting Abstract
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Huiskonen Erkko 2024-2027
Huiskonen, J. (Project manager), Poranen, M. (Project manager), Eshriew, E. K. (Participant), Sah Teli, S. K. (Participant), Song, X. (Participant) & Sun, X. (Participant)
01/11/2024 → 31/10/2027
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)
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How to package the RNA genome into a dsRNA viral replication complex
Sun, X. (Project manager)
Ella and Georg Ehrnrooth foundation
01/11/2023 → 31/10/2024
Project: Research project
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Assembly of the viral replication complex
Sun, X. (Project manager)
01/05/2021 → 31/12/2022
Project: Research project
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Environmental RNAi for pathogen control
Poranen, M. (Project manager), Levanova, A. (Participant), Marttila, H. (Participant), Mäntynen, S. S. (Participant), Sun, X. (Participant) & Westerholm, T. T. (Participant)
SUOMEN AKATEMIA Vähäkylä Leena
01/09/2020 → 31/08/2024
Project: Research Council of Finland: Academy Project
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Nucleation process as a potential antiviral target in assembly pathway of viral replication complex
Sun, X. (Project manager)
Jane and Aatos Erkko Foundation
01/01/2020 → 31/12/2020
Project: Research project
Prizes
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Chinese Government Award for Outstanding Students Abroad
Sun, X. (Recipient), 2014
Prize: Prizes and awards
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International Student Grant for outstanding undergraduate and graduate students
Sun, X. (Recipient), 27 Oct 2009
Prize: Prizes and awards
Activities
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TgK Hi-Tech Stopped-Flow Training Event
Sun, X. (Attendee)
18 Jan 2023 → 20 Jan 2023Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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NanoTemper Technologies workshop
Sun, X. (Attendee)
28 Feb 2023 → 1 Mar 2023Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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Instruct-ERIC Centre Finland Opening and Structural Biology Finland Conference 2021
Sun, X. (Attendee)
17 Dec 2021Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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WSV: Tackling Global Viral Epidemics 2021
Sun, X. (Attendee)
16 Jun 2021 → 18 Jun 2021Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
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EMBO course on laboratory leadership for postdocs
Sun, X. (Attendee)
22 Jun 2021 → 24 Jun 2021Activity: Participating in or organising an event types › Organisation and participation in conferences, workshops, courses, seminars
Press/Media
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Cryo-EM Reveals How a Virus Packages Its Genome
30/05/2019
1 item of Media coverage
Press/Media: Press / Media
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-UNIVERSITY OF HELSINKI: Unveiling how the genome has condensed itself inside the virus
30/05/2019
1 item of Media coverage
Press/Media: Press / Media
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Unveiling how the genome has condensed itself inside the virus
29/05/2019
5 items of Media coverage
Press/Media: Press / Media