Yulia Sidorova

Publications

Research output per year 2004 2020 2022

• 31 Article
• 7 Review Article
• 3 Meeting Abstract
• 1 Book
• 3 More
  • 1 Chapter
  • 1 Paper
  • 1 Other contribution

Research output per year

Research output per year

Search results

• 2022

  A Newly Identified Monoterpenoid-Based Small Molecule Able to Support the Survival of Primary Cultured Dopamine Neurons and Alleviate MPTP-Induced Toxicity In Vivo

  Kotliarova, A., Podturkina, A. V. V., Pavlova, A. V. V., Gorina, D. S. S., Lastovka, A. V. V., Ardashov, O. V. V., Rogachev, A. D. D., Izyurov, A. E. E., Arefieva, A. B. B., Kulikov, A. V. V., Tolstikova, T. G. G., Volcho, K. P. P., Salakhutdinov, N. F. F. & Sidorova, Y., Dec 2022, In: Molecules. 27, 23, 21 p., 8286.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• Biological Activity In Vitro, Absorption, BBB Penetration, and Tolerability of Nanoformulation of BT44: RET Agonist with Disease- Modifying Potential for the Treatment of Neurodegeneration

  Haider, M. S., Mahato, A. K., Kotliarova, A., Forster, S., Boettcher, B., Stahlhut, P., Sidorova, Y. & Luxenhofer, R., 11 Oct 2022, (E-pub ahead of print) In: Biomacromolecules. 18 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• Neurotrophic Factors to Combat Neurodegeneration

  Sidorova, Y. A., 2022, Frontiers in Clinical Drug Research - CNS and Neurological Disorders. Rahman, A. & Amtul, Z. (eds.). Bentham Science Publishers, Ltd. , Vol. 10. p. 132-187 56 p. (Frontiers in Clinical Drug Research - CNS and Neurological Disorders; no. 10).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Scientific › peer-review

  Open Access
• 2021

  Glial Cell Line-Derived Neurotrophic Factor Family Ligands, Players at the Interface of Neuroinflammation and Neuroprotection: Focus Onto the Glia

  Kotliarova, A. & Sidorova, Y. A., 17 Jun 2021, In: Frontiers in Cellular Neuroscience. 15, 13 p., 679034.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

  File

• Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats

  Renko, J-M., Mahato, A. K., Visnapuu, T., Valkonen, K., Karelson, M., Voutilainen, M. H., Saarma, M., Tuominen, R. K. & Sidorova, Y. A., 2021, In: Journal of Parkinson's disease. 11, 3, p. 1023-1046 24 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Spared Nerve Injury Causes Sexually Dimorphic Mechanical Allodynia and Differential Gene Expression in Spinal Cords and Dorsal Root Ganglia in Rats

  Ahlström, F. H. G., Mätlik, K., Viisanen, H., Blomqvist, K. J., Liu, X., Lilius, T. O., Sidorova, Y., Kalso, E. A. & Rauhala, P. V., Oct 2021, In: Molecular Neurobiology. 58, 10, p. 5396-5419 24 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2020

  Can Growth Factors Cure Parkinson's Disease?

  Sidorova, Y. A. & Saarma, M., Dec 2020, In: Trends in Pharmacological Sciences. 41, 12, p. 909-922 14 p.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

  File

• Detecting oxidative stress biomarkers in neurodegenerative disease models and patients

  Sidorova, Y. & Domanskyi, A., 2020, In: Methods and Protocols. 3, 4, 14 p., 66.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Glial cell line-derived neurotrophic factor receptor REarranged during transfection agonist supports dopamine neurons in Vitro and enhances dopamine release In Vivo

  Mahato, A. K., Kopra, J., Renko, J-M., Visnapuu, T., Korhonen, I., Pulkkinen, N., Bespalov, M. M., Domanskyi, A., Ronken, E., Piepponen, T. P., Voutilainen, M. H., Tuominen, R. K., Karelson, M., Sidorova, Y. A. & Saarma, M., Feb 2020, In: Movement Disorders. 35, 2, p. 245-255 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Glial cell line-derived neurotrophic factors (GFLs) and small molecules targeting RET receptor for the treatment of pain and Parkinson's disease

  Mahato, A. K. & Sidorova, Y. A., Oct 2020, In: Cell and Tissue Research. 382, 1, p. 147-160 14 p.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

  File

• Morphine-3-glucuronide causes antinociceptive cross-tolerance to morphine and increases spinal substance P expression

  Blomqvist, K., Viisanen, H., Ahlström, F. H. G., Jokinen, V., Sidorova, Y. A., Suleymanova, I., Rauhala, P. V., Kalso, E. A. & Lilius, T. O., 15 May 2020, In: European Journal of Pharmacology. 875, 9 p., 173021.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Novel RET agonist for the treatment of experimental neuropathies

  Viisanen, H., Nuotio, U., Kambur, O., Mahato, A. K., Jokinen, V., Lilius, T., Li, W., Santos, H. A., Karelson, M., Rauhala, P., Kalso, E. & Sidorova, Y. A., 18 Aug 2020, In: Molecular pain. 16, 19 p., 1744806920950866.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential

  Yadav, L., Pietilä, E., Öhman, T., Liu, X., Mahato, A. K., Sidorova, Y., Lehti, K., Saarma, M. & Varjosalo, M., 21 Feb 2020, In: iScience. 23, 2, 34 p., 100871.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• RET Receptor Tyrosine Kinase: Role in Neurodegeneration, Obesity, and Cancer

  Mahato, A. K. & Sidorova, Y. A., Oct 2020, In: International Journal of Molecular Sciences. 21, 19, 21 p., 7108.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

  File

• Small-molecule agonists of the RET receptor tyrosine kinase activate biased trophic signals that are influenced by the presence of GFRa1 co-receptors

  Jmaeff, S., Sidorova, Y., Nedev, H., Saarma, M. & Saragovi, H. U., 8 May 2020, In: Journal of Biological Chemistry. 295, 19, p. 6532-6542 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Small-Molecule Ligands that Bind the RET Receptor Activate Neuroprotective Signals Independent of but Modulated by Coreceptor GFR alpha 1

  Jmaeff, S., Sidorova, Y., Lippiatt, H., Barcelona, P. F., Nedev, H., Saragovi, L. M., Hancock, M. A., Saarma, M. & Saragovi, H. U., 1 Jul 2020, In: Molecular pharmacology : an international journal. 98, 1, p. 1-12 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Small Molecules and Peptides Targeting Glial Cell Line-Derived Neurotrophic Factor Receptors for the Treatment of Neurodegeneration

  Sidorova, Y. A. & Saarma, M., Sep 2020, In: International Journal of Molecular Sciences. 21, 18, 20 p., 6575.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

  File
• 2019

  A Novel Small Molecule Supports the Survival of Cultured Dopamine Neurons and May Restore the Dopaminergic Innervation of the Brain in the MPTP Mouse Model of Parkinson's Disease

  Ardashov, O. V., Pavlova, A. V., Mahato, A. K., Sidorova, Y., Morozova, E. A., Korchagina, D. V., Salnikov, G. E., Genaev, A. M., Patrusheva, O. S., Li-Zhulanov, N. S., Tolstikova, T. G., Volcho, K. P. & Salakhutdinov, N. F., Oct 2019, In: ACS chemical neuroscience. 10, 10, p. 4337-4349 25 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Gfra1 Underexpression Causes Hirschsprung's Disease and Associated Enterocolitis in Mice

  Porokuokka, L. L., Virtanen, H. T., Linden, J., Sidorova, Y., Danilova, T., Lindahl, M., Saarma, M. & Andressoo, J-O., 2019, In: Cellular and Molecular Gastroenterology and Hepatology. 7, 3, p. 655-678 24 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Neuroregeneration in Parkinson's Disease: From Proteins to Small Molecules

  Sidorova, Y., Volcho, K. P. & Slahytdinov, N. F., 2019, In: Current Neuropharmacology. 17, 3, p. 268-287 20 p.

  Research output: Contribution to journal › Review Article › peer-review
• 2018

  A deep convolutional neural network approach for astrocyte detection

  Suleymanova, I., Balassa, T., Tripathi, S., Molnar, C., Saarma, M., Sidorova, Y. & Horvath, P., 27 Aug 2018, In: Scientific Reports. 8, 7 p., 12878.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Differential Spinal and Supraspinal Activation of Glia in a Rat Model of Morphine Tolerance

  Jokinen, V., Sidorova, Y., Viisanen, H., Suleymanova, I., Tiilikainen, H., Li, Z., Lilius, T. O., Matlik, K., Anttila, J. E., Airavaara, M., Tian, L., Rauhala, P. V. & Kalso, E. A., 1 Apr 2018, In: Neuroscience. 375, p. 10-24 15 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• GDNF mimetics delivery by porous silicon nanoparticles for improved Parkinson’s disease management

  Li, W., Mäkilä, E., Salonen, J., Saarma, M., Sidorova, Y. & Almeida Santos, H., Jul 2018, p. 1848. 1 p.

  Research output: Conference materials › Paper › peer-review

• Molecular Dynamics Simulations of the Interactions between Glial Cell Line-Derived Neurotrophic Factor Family Receptor GFR alpha 1 and Small-Molecule Ligands

  Ivanova, L., Tammiku-Taul, J., Garcia-Sosa, A. T., Sidorova, Y., Saarma, M. & Karelson, M., Sep 2018, In: ACS Omega. 3, 9, p. 11407-11414 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Small-Molecule Ligands as Potential GDNF Family Receptor Agonists

  Ivanova, L., Tammiku-Taul, J., Sidorova, Y., Saarma, M. & Karelson, M., Jan 2018, In: ACS Omega. 3, 1, p. 1022-1030 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2017

  A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat

  Sidorova, Y. A., Bespalov, M. M., Wong, A. W., Kambur, O., Jokinen, V., Lilius, T. O., Suleymanova, I., Karelson, G., Rauhala, P. V., Karelson, M., Osborne, P. B., Keast, J. R., Kalso, E. A. & Saarma, M., 21 Jun 2017, In: Frontiers in Pharmacology. 8, 18 p., 365.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Quercetin Attenuates Benzo(α)pyrene-induced CYP1A Expression

  Seridina, T., Sidorova, Y., Perepechaeva, M. L., Pivovarova, E. N., Markel, A. L., Lyakhovich, V. V. & Grishanova, A. Y., 30 Apr 2017, In: Biomedical and Environmental Sciences. 4, p. 308-313

  Research output: Contribution to journal › Article › Scientific › peer-review

• Restoring dopaminergic nerve cells in Parkinson’s disease

  Ronken, E., Sidorova, Y., Karelson, M. & Saarma, M., 2017, In: Open access government. p. 25-26

  Research output: Contribution to journal › Article › General public

• Zebrafish GDNF and its co-receptor GFR alpha 1 activate the human RET receptor and promote the survival of dopaminergic neurons in vitro

  Saarenpää, T., Kogan, K., Sidorova, Y., Mahato, A. K., Tascon, I., Kaljunen, H., Yu, L., Kallijärvi, J., Jurvansuu, J., Saarma, M. & Goldman, A., 3 May 2017, In: PLoS One. 12, 5, 18 p., 0176166.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2016

  A new approach to treating Parkonson's disease

  Sidorova, Y., 2016, In: EU Research.

  Research output: Contribution to journal › Article › General public

• Glial cell line-derived neurotrophic factor family ligands and their therapeutic potential

  Sidorova, Y. A. & Saarma, M., Jul 2016, In: Molecular Biology. 50, 4, p. 521-531 11 p.

  Research output: Contribution to journal › Review Article › peer-review

• Menadione Suppresses Benzo(a)pyrene-Induced Activation of Cytochromes P450 1A: Insights into a Possible Molecular Mechanism

  Sidorova, Y. A., Perepechaeva, M. L., Pivovarova, E. N., Markel, A. L., Lyakhovich, V. V. & Grishanova, A. Y., 11 May 2016, In: PLoS One. 11, 5, 17 p., 0155135.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Novel agonist of GDNF family ligand receptor RET for the treatment of experimental neuropathy

  Bespalov, M., Sidorova, Y., Suleymanova, I., Thompson, J., Kambur, O., Jokinen, V., Lilius, T. O., Karelson, G., Puusepp, L., Rauhala, P. V., Kalso, E. A., Karelson, M. & Saarma, M., 4 Jul 2016, In: BioRxiv beta : the preprint server for biology.

  Research output: Contribution to journal › Article › Professional

  Open Access
• 2014

  Retinal neuroprotection using small molecule GDNF mimetics

  Saragovi, H. U., Sidorova, Y., Saarma, M. & Jmaeff, S., Apr 2014, In: Investigative Ophthalmology & Visual Science. 55, 13, 2 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review
• 2013

  A cure for Parkinson's disease in development

  Sidorova, Y., 2013

  Research output: Other contribution
• 2012

  Small Molecular Weight ARTN Mimetic for the Treatment of Neuropathic Pain

  Sidorova, Y. A., Bespalov, M. M., Karelson, M. & Saarma, M., 2012, In: Cell Transplantation. 21, 4, p. 792-792 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

• Weak CYP1A Inducers: A Potential Role in Prevention and Therapy of Chemically-Induced Cancer.

  Sidorova, Y., Perepechaeva, M. L. & Grishanova, A. Y., 2012

  Research output: Book/Report › Book › General public
• 2011

  Heparan sulfate proteoglycan syndecan-3 is a novel receptor for GDNF, neurturin, and artemin

  Bespalov, M. M., Sidorova, Y. A., Tumova, S., Ahonen-Bishopp, A., Magalhaes, A. C., Kulesskiy, E., Paveliev, M., Rivera Baeza, C., Rauvala, H. & Saarma, M., 2011, In: Journal of Cell Biology. 192, 1, p. 153-169 17 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2010

  Persephin signaling through GFR alpha 1: The potential for the treatment of Parkinson's disease

  Sidorova, Y., Mätlik, K., Paveliev, M., Lindahl, M., Piranen, E., Milbrandt, J., Arumäe, U., Saarma, M. & Bespalov, M., 2010, In: Molecular and Cellular Neuroscience. 44, 3, p. 223-232 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2009

  Heparin-binding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons

  Piltonen, M., Bespalov, M. M., Ervasti, D., Matilainen, T., Sidorova, Y. A., Rauvala, H., Saarma, M. & Männistö, P. T., 2009, In: Experimental Neurology. 219, 2, p. 499-506 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2008

  The structure of the glial cell line-derived neurotrophic factor-coreceptor complex: insights into RET signaling and heparin binding

  Parkash, V., Leppänen, V-M., Virtanen, H., Jurvansuu, J. M., Bespalov, M. M., Sidorova, Y. A., Runeberg-Roos, P., Saarma, M. & Goldman, A., 2008, In: Journal of Biological Chemistry. 283, 12, p. 35164-35172 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2007

  GDNF receptors as a drug target for neural repair

  Bespalov, M. M., Hetenyi, C., Turnova, S., Hienola, A., Sidorova, Y., Rauvala, H., Karelson, M. & Saarma, M., 2007, In: Cell Transplantation. 16, 3, p. 314-314 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review
• 2005

  Rat hepatic CYP1A1 and CYP1A2 induction by menadione

  Sidorova, YA., Grishanova, AY. & Lyakhovich, VV., 15 Feb 2005, In: Toxicology Letters. 155, 2, p. 253-258 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2004

  Dose- and time-dependent effects of menadione on enzymes of xenobiotic metabolism in rat liver

  Sidorova, YA. & Grishanova, AY., Mar 2004, In: Bulletin of Experimental Biology and Medicine. 137, 3, p. 231-234 4 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Transcriptional activation of cytochrome p450 1A1 with alpha-tocopherol

  Sidorova, YA., Grishanova, AY. & Lyakhovich, VV., Sep 2004, In: Bulletin of Experimental Biology and Medicine. 138, 3, p. 233-236 4 p.

  Research output: Contribution to journal › Article › Scientific › peer-review