20172020

Research output per year

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2020

All-in-one microfluidic assembly of insulin-loaded pH-responsive nano-in-microparticles for oral insulin delivery

Costa, C., Liu, Z., Martins, J. P., Correia, A., Rahikkala, A. T. A., Li, W., Seitsonen, J., Ruokolainen, J., Hirvonen, S-P., Aguiar- Ricardo, A., Corvo, M. L. & Santos, H. A., 21 Jun 2020, In : Biomaterials Science. 8, 12, p. 3270-3277 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Colorectal Cancer Triple Co-culture Spheroid Model to Assess the Biocompatibility and Anticancer Properties of Polymeric Nanoparticles

Bauleth-Ramos, T., Feijão, T., Gonçalves, A., Shahbazi, M-A., Liu, Z., Barrias, C., Oliveira, M. J., L. Granja, P., Santos, H. A. & Sarmento, B., 10 Jul 2020, In : Journal of Controlled Release. 323, p. 398-411 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Tandem-Mass-Tag based proteomic analysis facilitates analyzing critical factors of porous silicon nanoparticles in determining their biological responses under diseased condition

Li, Y., Liu, Z., Li, L., Lian, W., He, Y., Khalil, E., Makila, E., Zhang, W., Torrieri, G., Liu, X., Su, J., Xiu, Y., Fontana, F., Salonen, J., Hirvonen, J., Liu, W., Zhang, H., Santos, H. A. & Deng, X., 7 Aug 2020, In : Advanced Science. 7, 15, 12 p., 2001129.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2019

Biohybrid Vaccines for Improved Treatment of Aggressive Melanoma with Checkpoint Inhibitor

Fontana, F., Fusciello, M., Groeneveldt, C., Capasso, C., Chiaro, J., Feola, S., Liu, Z., Mäkilä, E., Salonen, J., Hirvonen, J., Cerullo, V. & Santos, H. A., Jun 2019, In : ACS Nano. 13, 6, p. 6477-6490 14 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Close-loop dynamic nanohybrids on collagen-ark with in situ gelling transformation capability for biomimetic stage-specific diabetic wound healing

Liu, Z., Li, Y., Li, W., Lian, W., Kemell, M., Hietala, S., Figueiredo, P., Li, L., Mäkilä, E., Ma, M., Salonen, J., Hirvonen, J. T., Liu, D., Zhang, H., Deng, X. & Santos, H. A., 1 Feb 2019, In : Materials Horizons. 6, 2, p. 385-393 9 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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2018

Biodegradable Spheres Protect Traumatically Injured Spinal Cord by Alleviating the Glutamate-Induced Excitotoxicity

Liu, D., Chen, J., Jiang, T., Li, W., Huang, Y., Lu, X., Liu, Z., Zhang, W., Zhou, Z., Ding, Q., Almeida Santos, H., Yin, G. & Fan, J., 5 Apr 2018, In : Advanced Materials. 30, 14, 11 p., 1706032.

Research output: Contribution to journalArticleScientificpeer-review

Dual‐drug delivery using dextran‐functionalized nanoparticles targeting cardiac fibroblasts for cellular reprogramming

Ferreira, M. P. A., Talman, V., Torrieri, G., Liu, D., Marques, G., Moslova, K., Liu, Z., Pinto, J. F., Hirvonen, J., Ruskoaho, H. & Santos, H. A., 11 Apr 2018, In : Advanced Functional Materials. 28, 15, 12 p., 1705134.

Research output: Contribution to journalArticleScientificpeer-review

Hierarchical structured and programmed vehicles deliver drugs locally to inflamed sites of intestine

Li, W., Li, Y., Liu, Z., Kerdsakundee, N., Zhang, M., Zhang, F., Liu, X., Bauleth-Ramos, T., Mäkilä, E., Kemell, M., Ding, Y., Sarmento, B., Wiwattanapatapee, R., Salonen, J., Zhang, H., Hirvonen, J. T., Liu, D., Deng, X. & Santos, H. A., Dec 2018, In : Biomaterials. 185, p. 322-332 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Multifunctional Nanohybrid Based on Porous Silicon Nanoparticles, Gold Nanoparticles and Acetalated Dextran for Liver Regeneration and Acute Liver Failure Theranostics

Liu, Z., Li, Y., Li, W., Xiao, C., Liu, D., Dong, C., Zhang, M., Mäkilä, E., Kemell, M., Salonen, J., Hirvonen, J. T., Zhang, H., Zhou, D., Deng, X. & Santos, H. A., 13 Jun 2018, In : Advanced Materials. 30, 24, 10 p., 1703393 .

Research output: Contribution to journalArticleScientificpeer-review

pH and Reactive Oxygen Species-Sequential Responsive Nano-in-Micro Composite For Targeted Therapy of Inflammatory Bowel Disease

Bertoni, S., Liu, Z., Rebelo Correia, A. M., Oliveira Martins, J. P., Rahikkala, A. T. A., Fontana, F., Kemell, M. L., Liu, D., Albertini, B., Passerini, N., Li, W. & Almeida Santos, H., 12 Dec 2018, In : Advanced Functional Materials. 28, 50, p. 1806175 11 p.

Research output: Contribution to journalArticleScientificpeer-review

2017

A Versatile Carbonic Anhydrase IX Targeting Ligand-Functionalized Porous Silicon Nanoplatform for Dual Hypoxia Cancer Therapy and Imaging

Janoniene, A., Liu, Z., Baranauskiene, L., Mäkilä, E., Ma, M., Salonen, J., Hirvonen, J., Zhang, H., Petrikaite, V. & Santos, H. A., 26 Apr 2017, In : ACS Applied Materials & Interfaces. 9, 16, p. 13976-13987 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Functionalization of Carboxylated Lignin Nanoparticles for Targeted and pH-Responsive Delivery of Anticancer Drugs

Figueiredo, P. I., Ferro, C., Kemell, M. L., Liu, Z., Kiriazis, A., Lintinen, K., Florindo, H., Yli-Kauhaluoma, J. T., Hirvonen, J. T., A. Kostiainen, M. & Almeida Santos, H., Oct 2017, In : Nanomedicine. 12, 21, p. 2581-2596 16 p.

Research output: Contribution to journalArticleScientificpeer-review

In Vitro Evaluation of Biodegradable Lignin-based Nanoparticles for Drug Delivery and Enhanced Antiproliferation Effect in Cancer Cells

Figueiredo, P., Lintinen, K., Kiriazis, A., Hynninen, V., Liu, Z., Bauleth-Ramos, T., Rahikkala, A., Correia, A., Kohout, T., Sarmento, B., Yli-Kauhaluoma, J. T., Hirvonen, J. T., Ikkala, O., A. Kostiainen, M. & Almeida Santos, H., Mar 2017, In : Biomaterials. 121, p. 97–108 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Microfluidic Encapsulation of Prickly Zinc-Doped Copper Oxide Nanoparticles with VD1142 Modified Spermine Acetalated Dextran for Efficient Cancer Therapy

Zhang, H., Liu, D., Wang, L., Liu, Z., Wu, R., Janoniene, A., Ma, M., Pan, G., Baranauskiene, L., Zhang, L., Cui, W., Petrikaite, V., Matulis, D., Zhao, H., Pan, J. & Santos, H. A., 7 Jun 2017, In : Advanced Healthcare Materials. 6, 11, 13 p., 1601406.

Research output: Contribution to journalArticleScientificpeer-review

Multifunctional Nanotube-Mucoadhesive Poly(methyl vinyl ether-co-maleic acid)@Hydroxypropyl Methylcellulose Acetate Succinate Composite for Site-Specific Oral Drug Delivery

Kerdsakundee, N., Li, W., Martins, J. P., Liu, Z., Zhang, F., Kemell, M., Correia, A., Ding, Y., Airavaara, M., Hirvonen, J., Wiwattanapatapee, R. & Santos, H. A., 25 Oct 2017, In : Advanced Healthcare Materials. 6, 20, 12 p., 1700629.

Research output: Contribution to journalArticleScientificpeer-review

Quercetin-Based Modified Porous Silicon Nanoparticles for Enhanced Inhibition of Doxorubicin-Resistant Cancer Cells

Liu, Z., Balasubramanian, V., Bhat, C., Vahermo, M., Mäkilä, E., Kemell, M., Fontana, F., Janoniene, A., Petrikaite, V., Salonen, J., Yli-Kauhaluoma, J., Hirvonen, J., Zhang, H. & A. Santos, H., 8 Feb 2017, In : Advanced Healthcare Materials. 6, 3, 11 p., 1601009.

Research output: Contribution to journalArticleScientificpeer-review