Research output per year
Research output per year
Personal profile
Fields of Science
- 3111 Biomedicine
International and National Collaboration
Publications and projects within past five years.
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Ebselen enhances insulin sensitivity and decreases oxidative stress by inhibiting SHIP2 and protects from inflammation in diabetic mice
Polianskyte-Prause, Z., Tolvanen, T. A., Lindfors, S., Kon, K., Hautala, L. C., Wang, H., Wada, T., Tsuneki, H., Sasaoka, T. & Lehtonen, S., 2022, In: International Journal of Biological Sciences. 18, 5, p. 1852-1864 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo
Lindfors, S., Polianskyte-Prause, Z., Bouslama, R., Lehtonen, E., Mannerla, M., Nisen, H., Tienari, J., Salmenkari, H., Forsgard, R., Mirtti, T., Lehto, M., Groop, PH. & Lehtonen, S., Aug 2021, In: Diabetologia. 64, 8, p. 1866-1879 14 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Metformin increases glucose uptake and acts renoprotectively by reducing SHIP2 activity
Polianskyte-Prause, Z., Tolvanen, T. A., Lindfors, S., Dumont, V., Van, M., Wang, H., Dash, S. N., Berg, M., Naams, J-B., Hautala, L. C., Nisen, H., Mirtti, T., Groop, P-H., Wähälä, K., Tienari, J. & Lehtonen, S., Feb 2019, In: FASEB Journal. 33, 2, p. 2858-2869 12 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
Metformin and the catalytic activity of SHIP2
Berg, M. E. A., Tolvanen, T. A., Polianskyte-Prause, Z., Lindfors, S. H., Wähälä, K. & Lehtonen, S. H., 27 Aug 2017, p. 125. 1 p.Research output: Conference materials › Poster
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A novel mechanism of action of metformin to ameliorate peripheral insulin resistance
Tolvanen, T. A., Polianskyte-Prause, Z., Lindfors, S. H., Wähälä, K. & Lehtonen, S. H., 2015, Emerging targets and molecules in middle space: Program & Abstracts. Wähälä, K., Koistinen, H. & Koskinen, A. (eds.). Helsinki: FInMedChem FInnish Pharmaceutical Society , 1 p.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific
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The mitochondrial serine protease LACTB and programmed cell death
Eriksson-Rosenberg, O., Polianskyte-Prause, Z., Peitsaro, N. & Dapkunas, A.
01/08/2008 → 31/12/2010
Project: Research project
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A new SHIP2 inhibitor enhances insulin sensitivity and attenuates kidney injury in diabetic db/db mice
Zydrune Polianskyte-Prause (Speaker)
24 May 2019Activity: Talk or presentation types › Oral presentation
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Metformin enhances insulin sensitivity and protects from kidney injury by inhibiting SHIP2 activity
Zydrune Polianskyte-Prause (Speaker)
19 May 2017Activity: Talk or presentation types › Oral presentation
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University of Toyama
Zydrune Polianskyte-Prause (Visiting researcher)
6 Oct 2016 → 22 Oct 2016Activity: Visiting an external institution types › Academic visit to other institution