Axon degeneration: new mechanisms, biomarkers and treatment

Project Details

Description

Three-year research project
StatusActive
Effective start/end date01/01/201731/12/2020

Funding

  • Valtion perusrahoitus/hankkeet: €30,000.00
  • FINSKA LÄKARESÄLLSKAPET RF: €10,000.00
  • University of Helsinki: €150,000.00
  • Academy of Finland: €278,070.00

Research Output

Loss of MICOS complex integrity and mitochondrial damage, but not TDP-43 mitochondrial localisation, are likely associated with severity of CHCHD10-related diseases

Genin, E. C., Bannwarth, S., Lespinasse, F., Ortega-Vila, B., Fragaki, K., Itoh, K., Villa, E., Lacas-Gervais, S., Jokela, M., Auranen, M., Ylikallio, E., Mauri-Crouzet, A., Tyynismaa, H., Vihola, A., Auge, G., Cochaud, C., Sesaki, H., Ricci, J-E., Udd, B., Vives-Bauza, C. & 1 others, Paquis-Flucklinger, V., Nov 2018, In : Neurobiology of Disease. 119, p. 159-171 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File

Recessive PYROXD1 mutations cause adult-onset limb-girdle-type muscular dystrophy

Sainio, M. T., Välipakka, S., Rinaldi, B., Lapatto, H., Paetau, A., Ojanen, S., Brilhante, V., Jokela, M., Huovinen, S., Auranen, M., Palmio, J., Friant, S., Ylikallio, E., Udd, B. & Tyynismaa, H., 4 Dec 2018, In : Journal of Neurology. p. 353-360 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
Open Access
File

Activities

Neuroliitto; Spastinen parapareesi

Emil Ylikallio (Speaker: Presenter)

13 Apr 2018

Activity: Participating in or organising an event typesPublic Talks

King's College London

Rosa Woldegebriel (Visiting researcher)

20182019

Activity: Visiting an external institution typesAcademic visit to other institution

A national registry of motor neuron disease

Emil Ylikallio (Speaker)

31 May 2018

Activity: Talk or presentation typesOral presentation