Cerebral small vessel disease - preparing for RCT

Search results

• 2025

  Alzheimerin taudin biologisten lääkkeiden turvallisuus riippuu aivojen pienten suonten integriteetistä

  Melkas, S., Korvenoja, A. & Jokinen, H., 31 Oct 2025, In: Suomen lääkärilehti. 80, e45992.

  Research output: Contribution to journal › Comment/debate › Professional

  Open Access

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• Executive functions and processing speed in covert cerebral small vessel disease

  Jokinen, H., Laakso, H. M., Arola, A., Paajanen, T., Virkkala , J., Särkämö, T., Makkonen, T., Kyläheiko, I. S., Heinonen, H., Pitkänen, J., Korvenoja, A. & Melkas, S., Jan 2025, In: European Journal of Neurology. 32, 1, 9 p., e16533.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• The Sleep Puzzle: Linking Glymphatic Function to Cognitive Decline

  Ahlström, M. E. & Sihvonen, A., Dec 2025, In: European Journal of Neurology. 32, 12, 2 p., e70451.

  Research output: Contribution to journal › Editorial › Scientific

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• 2024

  European Stroke Organisation (ESO) Guideline on Cerebral Small Vessel Disease, Part 2, Lacunar Ischaemic Stroke

  Wardlaw, J. M., Chabriat, H., de Leeuw, F.-E., Debette, S., Dichgans, M., Doubal, F., Jokinen, H., Katsanos, A., Ornello, R., Pantoni, L., Pasi, M., Pavlovic, A. M., Rudilosso, S., Schmidt, R., Staals, J., Taylor-Rowan, M., Hussain, S. & Lindgren, A. G., Mar 2024, In: European Stroke Journal. 9, 1, p. 5-68 64 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• In memoriam, Timo Juha Erkinjuntti, MD PhD, Professor in Neurology, University of Helsinki, Finland

  Pantoni, L., Jokinen, H., Melkas, S. & Kalaria, R., 30 Aug 2024, In: Cerebral circulation, cognition and behavior. 7, 3 p., 100365.

  Research output: Contribution to journal › Article › Scientific

  Open Access

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• 2023

  Neurofilament light level correlates with brain atrophy, and cognitive and motor performance

  Kartau, M., Melkas, S., Kartau, J., Arola, A., Laakso, H., Pitkänen, J., Lempiäinen, J., Koikkalainen, J., Lötjönen, J., Korvenoja, A., Ahlström, M., Herukka, S.-K., Erkinjuntti, T. & Jokinen, H., 5 Jan 2023, In: Frontiers in aging neuroscience. 14, 8 p., 939155.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Neuroimaging standards for research into small vessel disease—advances since 2013

  Duering, M., Biessels, G. J., Brodtmann, A., Chen, C., Cordonnier, C., de Leeuw, F.-E., Debette, S., Frayne, R., Jouvent, E., Rost, N. S., ter Telgte, A., Al-Shahi Salman, R., Backes, W. H., Bae, H.-J., Brown, R., Chabriat, H., De Luca, A., deCarli, C., Dewenter, A. & Doubal, F. N. & 34 others, Ewers, M., Field, T. S., Ganesh, A., Greenberg, S., Helmer, K. G., Hilal, S., Jochems, A. C. C., Jokinen, H., Kuijf, H., Lam, B. Y. K., Lebenberg, J., MacIntosh, B. J., Maillard, P., Mok, V. C. T., Pantoni, L., Rudilosso, S., Satizabal, C. L., Schirmer, M. D., Schmidt, R., Smith, C., Staals, J., Thrippleton, M. J., van Veluw, S. J., Vemuri, P., Wang, Y., Werring, D., Zedde, M., Akinyemi, R. O., Del Brutto, O. H., Markus, H. S., Zhu, Y.-C., Smith, E. E., Dichgans, M. & Wardlaw, J. M., 2023, In: Lancet Neurology. 22, 7, p. 602-618 17 p.

  Research output: Contribution to journal › Review Article › peer-review

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• Neuropsychiatric symptoms are associated with exacerbated cognitive impairment in covert cerebral small vessel disease

  Arola, A., Levänen, T., Laakso, H. M., Pitkänen, J., Koikkalainen, J., Lötjönen, J., Korvenoja, A., Erkinjuntti, T., Melkas, S. & Jokinen, H., Jun 2023, In: Journal of the International Neuropsychological Society. 29, 5, p. 431-438 8 p., 1355617722000480.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Subjective vs informant-reported cognitive complaints have differential clinical significance in covert cerebral small vessel disease

  Arola, A., Laakso, H. M., Heinonen, H., Pitkänen, J., Ahlström, M., Lempiäinen, J. E., Paajanen, T., Virkkala , J., Koikkalainen, J., Lötjönen, J., Korvenoja, A., Melkas, S. & Jokinen, H., 16 Sept 2023, In: Cerebral circulation, cognition and behavior. 5, 7 p., 100182.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• 2022

  Synergistic associations of cognitive and motor impairments with functional outcome in covert cerebral small vessel disease

  Jokinen, H., Laakso, H. M., Ahlström, M., Arola, A., Lempiäinen, J., Pitkänen, J., Paajnen, T., Sikkes, S. A. M., Koikkalainen, J., Lötjönen, J., Korvenoja, A., Erkinjuntti, T. & Melkas, S., Jan 2022, In: European Journal of Neurology. 29, 1, p. 158-167 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• 2021

  Associations of cognitive reserve and psychological resilience with cognitive functioning in subjects with cerebral white matter hyperintensities

  Arola, A., Laakso, H. M., Pitkänen, J., Koikkalainen, J., Lötjönen, J., Korvenoja, A., Erkinjuntti, T., Melkas, S. & Jokinen, H., Aug 2021, In: European Journal of Neurology. 28, 8, p. 2622-2630 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• ESO Guideline on Covert Cerebral Small Vessel Disease

  Wardlaw, J. M., Debette, S., Jokinen, H., De Leeuw, F.-E., Pantoni, L., Chabriat, H., Staals, J., Doubal, F., Rudilosso, S., Eppinger, S., Schilling, S., Ornello, R., Enzinger, C., Cordonnier, C., Taylor-Rowan, M. & Lindgren, A. G., Jun 2021, In: European Stroke Journal. 6, 2, p. CXI-CLXII 52 p., 23969873211012132.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• 2020

  The influence of diversity on the measurement of functional impairment: An international validation of the Amsterdam IADL questionnaire in 8 countries

  Dubbelman, M. A., Verrijp, M., Facal, D., Sánchez-Benavides, G., Brown, L. J. E., Flier, W. M. V. D., Jokinen, H., Lee, A., Leroi, I., Lojo-Seoane, C., Milosevic, V., Molinuevo, J. L., Rozas, A. X. P., Ritchie, C., Salloway, S., Stringer, G., Zygouris, S., Dubois, B., Epelbaum, S. & Scheltens, P. & 1 others, Sikkes, S. A. M., 2020, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 12, 1, 11 p., e12021.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Voidaanko aivojen valkean aineen muutoksia ehkäistä?

  Melkas, S., Rantanen, K., Strandberg, T., Erkinjuntti, T. J. & Jokinen, H., 2020, In: Duodecim. 136, 11, p. 1291-1299 9 p.

  Research output: Contribution to journal › Review Article › peer-review

  Open Access

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