Consortium for Refractive Error and Myopia

Wedenoja, Juho (Principal Investigator)
Pärssinen, Olavi (Principal Investigator)
Kaprio, Jaakko (Project manager)

Project: Research project

Description (abstract)

The CREAM consortium consists of more than 50 genetics studies from all over the world involved in the elucidation of the complex pathogenesis of myopia and related phenotypes.

Acronym	CREAM
Status	Active
Effective start/end date	01/01/2012 → …

3 Article

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium
Li, Q., Wojciechowski, R., Simpson, C. L., Hysi, P. G., Verhoeven, V. J. M., Ikram, M. K., Hoehn, R., Vitart, V., Hewitt, A. W., Oexle, K., Makela, K.-M., MacGregor, S., Pirastu, M., Fan, Q., Cheng, C.-Y., St Pourcain, B., McMahon, G., Kemp, J. P., Northstone, K. & Rahi, J. S. & 70 others, Cumberland, P. M., Martin, N. G., Sanfilippo, P. G., Lu, Y., Wang, Y. X., Hayward, C., Polasek, O., Campbell, H., Bencic, G., Wright, A. F., Wedenoja, J., Zeller, T., Schillert, A., Mirshahi, A., Lackner, K., Yip, S. P., Yap, M. K. H., Ried, J. S., Gieger, C., Murgia, F., Wilson, J. F., Fleck, B., Yazar, S., Vingerling, J. R., Hofman, A., Uitterlinden, A., Rivadeneira, F., Amin, N., Karssen, L., Oostra, B. A., Zhou, X., Teo, Y.-Y., Tai, E. S., Vithana, E., Barathi, V., Zheng, Y., Siantar, R. G., Neelam, K., Shin, Y., Lam, J., Yonova-Doing, E., Venturini, C., Hosseini, S. M., Wong, H.-S., Lehtimaki, T., Kahonen, M., Raitakari, O., Timpson, N. J., Evans, D. M., Khor, C.-C., Aung, T., Young, T. L., Mitchell, P., Klein, B., van Duijn, C. M., Meitinger, T., Jonas, J. B., Baird, P. N., Mackey, D. A., Wong, T. Y., Saw, S.-M., Parssinen, O., Stambolian, D., Hammond, C. J., Klaver, C. C. W., Williams, C., Paterson, A. D., Bailey-Wilson, J. E., Guggenheim, J. A. & CREAM Consortium, Feb 2015, In: Human Genetics. 134, 2, p. 131-146 16 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia
Verhoeven, V. J. M., Hysi, P. G., Wojciechowski, R., Fan, Q., Guggenheim, J. A., Hoehn, R., MacGregor, S., Hewitt, A. W., Nag, A., Cheng, C.-Y., Yonova-Doing, E., Zhou, X., Ikram, M. K., Buitendijk, G. H. S., McMahon, G., Kemp, J. P., St Pourcain, B., Simpson, C. L., Makela, K.-M. & Lehtimaki, T. & 34 others, Kahonen, M., Paterson, A. D., Hosseini, S. M., Wong, H. S., Xu, L., Jonas, J. B., Parssinen, O., Wedenoja, J., Yip, S. P., Ho, D. W. H., Pang, C. P., Chen, L. J., Burdon, K. P., Craig, J. E., Klein, B. E. K., Klein, R., Haller, T., Metspalu, A., Khor, C.-C., Tai, E.-S., Aung, T., Vithana, E., Tay, W.-T., Barathi, V. A., Chen, P., Li, R., Liao, J., Zheng, Y., Ong, R. T., Doering, A., CREAM, Diabet Control Complications Trial, WTCCC2 & Fuchs' Genetics Multi-Ctr Study Gr, Mar 2013, In: Nature Genetics. 45, 3, p. 314-318 5 p.
Research output: Contribution to journal › Article › Scientific › peer-review
Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error
Cheng, C.-Y., Schache, M., Ikram, M. K., Young, T. L., Guggenheim, J. A., Vitart, V., MacGregor, S., Verhoeven, V. J. M., Barathi, V. A., Liao, J., Hysi, P. G., Bailey-Wilson, J. E., St Pourcain, B., Kemp, J. P., McMahon, G., Timpson, N. J., Evans, D. M., Montgomery, G. W., Mishra, A. & Wang, Y. X. & 34 others, Wang, J. J., Rochtchina, E., Polasek, O., Wright, A. F., Amin, N., van Leeuwen, E. M., Wilson, J. F., Pennell, C. E., van Duijn, C. M., de Jong, P. T. V. M., Vingerling, J. R., Zhou, X., Chen, P., Li, R., Tay, W.-T., Zheng, Y., Chew, M., Burdon, K. P., Craig, J. E., Iyengar, S. K., Igo, R. P., Lass, J. H., Chew, E. Y., Haller, T., Mihailov, E., Metspalu, A., Wedenoja, J., Simpson, C. L., Wojciechowski, R., Hoehn, R., Consortium Refractive Error Myopia, Fuchs Genetics Multictr Study Grp, Wellcome Trust Case Control Consor & Diabet Control Complications Trial, 8 Aug 2013, In: American Journal of Human Genetics. 93, 2, p. 264-277 14 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Consortium for Refractive Error and Myopia

Project Details

Description (abstract)

Research output

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error