Consortium for Refractive Error and Myopia

Project: Research project

Project Details

Description (abstract)

The CREAM consortium consists of more than 50 genetics studies from all over the world involved in the elucidation of the complex pathogenesis of myopia and related phenotypes.
Effective start/end date01/01/2012 → …
  • Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

    Li, Q., Wojciechowski, R., Simpson, C. L., Hysi, P. G., Verhoeven, V. J. M., Ikram, M. K., Hoehn, R., Vitart, V., Hewitt, A. W., Oexle, K., Makela, K-M., MacGregor, S., Pirastu, M., Fan, Q., Cheng, C-Y., St Pourcain, B., McMahon, G., Kemp, J. P., Northstone, K., Rahi, J. S., & 70 othersCumberland, P. M., Martin, N. G., Sanfilippo, P. G., Lu, Y., Wang, Y. X., Hayward, C., Polasek, O., Campbell, H., Bencic, G., Wright, A. F., Wedenoja, J., Zeller, T., Schillert, A., Mirshahi, A., Lackner, K., Yip, S. P., Yap, M. K. H., Ried, J. S., Gieger, C., Murgia, F., Wilson, J. F., Fleck, B., Yazar, S., Vingerling, J. R., Hofman, A., Uitterlinden, A., Rivadeneira, F., Amin, N., Karssen, L., Oostra, B. A., Zhou, X., Teo, Y-Y., Tai, E. S., Vithana, E., Barathi, V., Zheng, Y., Siantar, R. G., Neelam, K., Shin, Y., Lam, J., Yonova-Doing, E., Venturini, C., Hosseini, S. M., Wong, H-S., Lehtimaki, T., Kahonen, M., Raitakari, O., Timpson, N. J., Evans, D. M., Khor, C-C., Aung, T., Young, T. L., Mitchell, P., Klein, B., van Duijn, C. M., Meitinger, T., Jonas, J. B., Baird, P. N., Mackey, D. A., Wong, T. Y., Saw, S-M., Parssinen, O., Stambolian, D., Hammond, C. J., Klaver, C. C. W., Williams, C., Paterson, A. D., Bailey-Wilson, J. E., Guggenheim, J. A. & CREAM Consortium, Feb 2015, In: Human Genetics. 134, 2, p. 131-146 16 p.

    Research output: Contribution to journalArticleScientificpeer-review

    Open Access
  • Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

    Verhoeven, V. J. M., Hysi, P. G., Wojciechowski, R., Fan, Q., Guggenheim, J. A., Hoehn, R., MacGregor, S., Hewitt, A. W., Nag, A., Cheng, C-Y., Yonova-Doing, E., Zhou, X., Ikram, M. K., Buitendijk, G. H. S., McMahon, G., Kemp, J. P., St Pourcain, B., Simpson, C. L., Makela, K-M., Lehtimaki, T., & 34 othersKahonen, M., Paterson, A. D., Hosseini, S. M., Wong, H. S., Xu, L., Jonas, J. B., Parssinen, O., Wedenoja, J., Yip, S. P., Ho, D. W. H., Pang, C. P., Chen, L. J., Burdon, K. P., Craig, J. E., Klein, B. E. K., Klein, R., Haller, T., Metspalu, A., Khor, C-C., Tai, E-S., Aung, T., Vithana, E., Tay, W-T., Barathi, V. A., Chen, P., Li, R., Liao, J., Zheng, Y., Ong, R. T., Doering, A., CREAM, Diabet Control Complications Trial, WTCCC2 & Fuchs' Genetics Multi-Ctr Study Gr, Mar 2013, In: Nature Genetics. 45, 3, p. 314-318 5 p.

    Research output: Contribution to journalArticleScientificpeer-review

  • Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error

    Cheng, C-Y., Schache, M., Ikram, M. K., Young, T. L., Guggenheim, J. A., Vitart, V., MacGregor, S., Verhoeven, V. J. M., Barathi, V. A., Liao, J., Hysi, P. G., Bailey-Wilson, J. E., St Pourcain, B., Kemp, J. P., McMahon, G., Timpson, N. J., Evans, D. M., Montgomery, G. W., Mishra, A., Wang, Y. X., & 34 othersWang, J. J., Rochtchina, E., Polasek, O., Wright, A. F., Amin, N., van Leeuwen, E. M., Wilson, J. F., Pennell, C. E., van Duijn, C. M., de Jong, P. T. V. M., Vingerling, J. R., Zhou, X., Chen, P., Li, R., Tay, W-T., Zheng, Y., Chew, M., Burdon, K. P., Craig, J. E., Iyengar, S. K., Igo, R. P., Lass, J. H., Chew, E. Y., Haller, T., Mihailov, E., Metspalu, A., Wedenoja, J., Simpson, C. L., Wojciechowski, R., Hoehn, R., Consortium Refractive Error Myopia, Fuchs Genetics Multictr Study Grp, Wellcome Trust Case Control Consor & Diabet Control Complications Trial, 8 Aug 2013, In: American Journal of Human Genetics. 93, 2, p. 264-277 14 p.

    Research output: Contribution to journalArticleScientificpeer-review