EC-FP7-KBBE-2009-3-2-01-245137: Exploring Marine Resources for Bioactive Compounds: From Discovery to Sustainable Production and Industrial Applications (MAREX)

Research output

Research output per year 2014 2015 2016 2017 2020

• 18 Article

Research output per year

Research output per year

Search results

• 2020

  Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors

  Skok, Ž., Barančoková, M., Benek, O., Cruz, C. D., Tammela, P., Tomašič, T., Zidar, N., Mašič, L. P., Zega, A., Stevenson, C. E. M., Mundy, J. E. A., Lawson, D. M., Maxwell, A., Kikelj, D. & Ilaš, J., 10 Dec 2020, In: ACS Medicinal Chemistry Letters. 11, 12, p. 2433-2440 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2019

  Inhibition of Hepatitis C replication by targeting the molecular chaperone Hsp90 - synthesis and biological evaluation of 4,5,6,7-tetrahydrobenzo[1,2-d]thiazole derivatives

  Lillsunde, K.-E. M., Tomašič, T., Schult, P., Lohmann, V., Kikelj, D. & Tammela, P., 5 Feb 2019, In: ChemMedChem : chemistry enabling drug discovery.. 14, 3, p. 334-342 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access
• 2018

  Marine Microalgae: Promising Source for New Bioactive Compounds

  de Vera, C. R., Díaz Crespín, G., Hernández Daranas, A., Montalvão Looga, S., Lillsunde, K.-E., Tammela, P., Perälä, M., Hongisto, V., Virtanen, J., Rischer, H., Muller, C. D., Norte, M., Fernández, J. J. & Souto, M. L., 6 Sept 2018, In: Marine Drugs. 16, 9, 12 p., 317.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Synthesis and Antiproliferative Activity of Marine Bromotyrosine Purpurealidin I and Its Derivatives

  Bhat, C., Ilina, P., Tilli, I., Vorácová, M., Bruun, T., Barba, V., Hribernik, N., Lillsunde, K.-E., Mäki-Lohiluoma, E., Rüffer, T., Lang, H., Yli-Kauhaluoma, J., Kiuru, P. & Tammela, P., 3 Dec 2018, In: Marine Drugs. 16, 12, 26 p., 481.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2017

  Design, synthesis and biological evaluation of 4,5-dibromo-N-(thiazol-2-yl)-1H-pyrrole-2-carboxamide derivatives as novel DNA gyrase inhibitors

  Tomašič, T., Mirt, M., Barančoková, M., Ilaš, J., Zidar, N., Tammela, P. S. M. & Kikelj, D., 1 Jan 2017, In: Bioorganic & Medicinal Chemistry. 25, 1, p. 338-349 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Design, Synthesis and Evaluation of Novel Tyrosine-Based DNA Gyrase B Inhibitors

  Cotman, A., Trampuž, M., Brvar, M., Kikelj, D., Ilaš, J., Peterlin-Mašič, L., Montalvao, S. I. G. H., Tammela, P. S. M. & Frlan, R., Aug 2017, In: Archiv der Pharmazie : Chemistry in life sciences. 350, 8, 16 p., 1700087 .

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors

  Jakopin, Z., Ilas, J., Barancokova, M., Brvar, M., Tammela, P., Dolenc, M. S., Tomasic, T. & Kikelj, D., 21 Apr 2017, In: European Journal of Medicinal Chemistry. 130, p. 171-184 14 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  File

• Marine alkaloid oroidin analogues with antiviral potential: a novel class of synthetic compounds targeting the cellular chaperone Hsp90

  Lillsunde, K.-E., Tomašič, T., Kikelj, D. & Tammela, P., Dec 2017, In: Chemical Biology and Drug Design (Print). 90, 6, p. 1147-1154 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File
• 2016

  Discovery of bentzothiazole scaffold-based DNA gyrase B inhibitors

  Gjorgjieva, M., Tomašič, T., Barančokova, M., Katsamakas, S., Ilaš, J., Tammela, P., Peterlin Mašič, L. & Kikelj, D., Oct 2016, In: Journal of Medicinal Chemistry. 59, 19, p. 8941-8954 14 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Large-scale bioprospecting of cyanobacteria, micro- and macroalgae from the Aegean Sea

  Montalvao, S. I. G. H., Demirel, Z., Devi, P., Lombardi, V., Hongisto, V., Perälä, M., Hattara, J., Imamoglu, E., Shet Tilvi, S., Turan, G., Conk Dalay, M. & Tammela, P. S. M., 1 Mar 2016, In: New Biotechnology. 33, 3, p. 399-406 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• New N-phenyl-4,5-dibromopyrrolamides and N-phenylindolamides as ATPase inhibitors of DNA gyrase

  Zidar, N., Tomasic, T., Macut, H., Sirc, A., Brvar, M., Montalvao, S., Tammela, P., Ilas, J. & Kikelj, D., 30 Mar 2016, In: European Journal of Medicinal Chemistry. 117, p. 197-211 15 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Synthesis and Biological Evaluation of 2-Aminobenzothiazole and Benzimidazole Analogs Based on the Clathrodin Structure

  Montalvao, S., Leino, T. O., Kiuru, P. S., Lillsunde, K.-E., Yli-Kauhaluoma, J. & Tammela, P., 2 Feb 2016, In: Archiv der Pharmazie : Chemistry in life sciences. 349, 2, p. 137-149 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Synthesis and biological evaluation of crown ether acyl derivatives

  Febles, M., Montalvao, S. I. G. H., Crespín, G. D., Norte, M., Padrón, J. M., Tammela, P. S. M., Fernández, J. J. & Daranas, A. H., Nov 2016, In: Bioorganic & Medicinal Chemistry Letters. 26, 22, p. 5591-5593 3 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• 2015

  Baltic cyanobacteria - a source of biologically active compounds

  Mazur-Marzec, H., Błaszczyk, A., Felczykowska, A., Hohlfeld, N., Kobos, J., Toruńska-Sitarz, A., Devi, P., Montalvao, S., D'Souza, L., Tammela, P., Mikosik, A., Bloch, S., Nejman-Faleńczyk, B. & Węgrzyn, G., Jul 2015, In: European Journal of Phycology. 50, 3, p. 343-360 18 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Discovery of 4,5,6,7-tetrahydrobenzo[1,2-d]thiazoles as novel DNA gyrase inhibitors targeting the ATP-binding site

  Tomašič, T., Katsamakas, S., Hodnik, Ž., Ilaš, J., Brvar, M., Solmajer, T., Montalvao, S., Tammela, P., Banjanac, M., Ergović, G., Anderluh, M., Peterlin Mašič, L. & Kikelj, D., 23 Jul 2015, In: Journal of Medicinal Chemistry. 58, 14, p. 5501-5521 21 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• N-Phenyl-4,5-dibromopyrrolamides and N-phenylindolamides as ATP competitive DNA gyrase B Inhibitors: Design, synthesis, and evaluation

  Zidar, N., Macut, H., Tomašič, T., Brvar, M., Montalvao, S., Tammela, P., Solmajer, T., Peterlin Mašič, L., Ilaš, J. & Kikelj, D., 2015, In: Journal of Medicinal Chemistry. 58, 15, p. 6179-6194 16 p.

  Research output: Contribution to journal › Article › Scientific › peer-review
• 2014

  Bioactive cembrane derivatives from the Indian Ocean soft coral, Sinularia kavarattiensis

  Lillsunde, K.-E., Festa, C., Adel, H., De Marino, S., Lombardi, V., Tilvi, S., Nawrot, D., Zampella, A., D'Souza, L., D'Auria, M. V. & Tammela, P., 3 Jul 2014, In: Marine Drugs. 12, 7, p. 4045-4068 24 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

  File

• Exploring Marine Resources for Bioactive Compounds

  Kiuru, P., D'Auria, M. V., Muller, C. D., Tammela, P., Vuorela, H. & Yli-Kauhaluoma, J., Sept 2014, In: Planta Medica. 80, 14, p. 1234-1246 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review