Modulation of post-transcriptional transfer RNA modification as an enhancer of chemotherapeutic agents

Sarin, Peter (Project manager)
Gregorova, Pavlina (Participant)
Heinonen, Minna-Maria Kristiina (Participant)
Nordman, Erika Mikaela (Participant)
Gregorova, Pavlina (Participant)
Laarne, Milla Marjaana (Participant)

Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)

Acronym	CHEMODI
Status	Active
Effective start/end date	01/05/2022 → 30/04/2026

Funding

Sigrid Juséliuksen Säätiö @003701165704@: €187,044.67

Fields of Science

1182 Biochemistry, cell and molecular biology
Cancer
Protein synthesis
Transfer RNA
Post-transcriptional nucleoside modification

Biomolecular Complex Purification Facility (LS-RIA/ Instruct-HiLIFE)
Poranen, M. M. (Manager), Oksanen, H. M. (Other) & Eskelin, K. J. (Other)
Faculty of Biological and Environmental Sciences
Facility/equipment: Core Facility
Viikki Metabolomics Unit (LS-RIA/ Metabo-HiLIFE)
Sipari, N. (Manager)
Faculty of Biological and Environmental Sciences
Facility/equipment: Core Facility

1 Finished

Translation and neoplasia – the multifaceted role of post-transcriptional transfer RNA modification
Sarin, P. (Project manager), Gregorova, P. (Participant), Gregorova, P. (Participant), Heinonen, M.-M. K. (Participant) & Laarne, M. M. (Participant)
Sigrid Juseliuksen Säätiö, Sigrid Juselius Foundation, Sigrid Juséliuksen Säätiö @003701165704@
01/05/2020 → 31/12/2022
Project: Foundations (Private Foundations, Non-Profit Foundations, Charitable Trusts)

1 Article

Purification of micrococcal nuclease for use in ribosomal profiling of high-salinity extremophiles
Gregorova, P., Isada, M., DiRuggiero, J. & Sarin, P., Jan 2025, In: Journal of Biological Chemistry. 301, 1, 11 p., 108020.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File

2 Oral presentation
1 Supervisor or co-supervisor of doctoral thesis

Codon and Conquer – The Faceted Roles of tRNA in Infection
Sarin, P. (Speaker)
10 Jan 2023
Activity: Talk or presentation types › Oral presentation
Post-transcriptional modifications - the M&Ms of translation
Sarin, P. (Speaker)
3 Jun 2022
Activity: Talk or presentation types › Oral presentation
Pavlína Gregorová
Sarin, P. (Supervisor)
Aug 2017 → …
Activity: Examination types › Supervisor or co-supervisor of doctoral thesis