Oligopeptidase inhibitors in brain function and dysfunction: towards new therapeutic strategies for neuroprotection

Project: Research project

Status	Finished
Effective start/end date	03/10/2008 → 15/12/2012

Access Project

Deficiency of prolyl oligopeptidase in mice disturbs synaptic plasticity and reduces anxiety-like behaviour, body weight, and brain volume
Höfling, C., Kulesskaya, N., Jaako, K., Peltonen, I., Männistö, P. T., Nurmi, A., Vartiainen, N., Morawski, M., Zharkovsky, A., Voikar, V., Rossner, S. & Garcia Horsman, J. A., Jun 2016, In: European Neuropsychopharmacology. 26, 6, p. 1048-1061 14 p.
Research output: Contribution to journal › Article › Scientific › peer-review
Alteration of Brain expression of prolyl endopeptidase in animal model of minimal hepatic encephalopathy.
Addaoudi, K., Hernandez-Rabaza, V., Garcia-Horsman, A., Vicente, F., Tenorio, J. & Errami, M., 8 Aug 2015, In: International Journal of Innovative Science, Engineering & Technology. 2, 8, p. 838-843 6 p.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients
Tenorio-Laranga, J., Montoliu, C., Urios, A., Hernandez-Rabaza, V., Ahabrach, H., Garcia Horsman, J. A. & Felipo, V., 30 Sept 2015, In: Journal of Neuroinflammation. 12, 14 p., 183.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access