Rare Cancers Research Group

Search results

• 2026

  Antiviral regulator TRIM25 as a prognostic marker of better survival in Merkel cell carcinoma: Association with MCPyV status

  Fagerstedt, K. W., Kilpinen, S., Arola, J., Sundqvist, B. Z., Böhling, T., Andersson, L. C. & Sihto, H., 14 Feb 2026, In: International Journal of Cancer. n/a, n/a, 11 p., PMID 42124.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• RNA-Sequencing Reveals Two Subgroups of Eccrine Porocarcinomas and Poromas

  Puttonen, M., Kilpinen, S., von Willebrand, M., Ojala, K., Böhling, T., Koljonen, V. & Sihto, H., 14 Apr 2026, In: Journal of Cellular and Molecular Medicine. 30, 8, 11 p., e71140.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• 2025

  Clinicopathological comparison of eccrine poroma and porocarcinoma: Ki-67 index is not a decisive factor

  Meriläinen, A.-S., Sihto, H., Isola, J. & Koljonen, V., 30 May 2025, In: PLoS One. 20, 5, 9 p., e0324975.

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• Fibroblast growth factor receptor expression in hemangioblastomas: A novel therapeutic target

  Puttonen, M., Tynninen, O., Salmikangas, S., Vesterinen, T., Sihto, H. & Böhling, T., 20 May 2025, In: PLoS One. 20, 5, 16 p., e0323979.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• High YEATS4 expression characterizes MDM2-amplified liposarcoma

  Mariani, A., Sampo, M., Sihto, H., Böhling, T. & Youssef, O., Nov 2025, In: Cancer Genetics. 298, p. 10-15 6 p.

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• IGF2BP3 as a Prognostic Biomarker and Regulator of Metastasis in Merkel Cell Carcinoma

  Yang, Y., Gao, J., Shi, H., Sihto, H., Kilpinen, S., Vilcot, F., Janská, L., Jeschonneck, J., Cvetanovic, T., Höög, A., Siarov, J., Paoli, J., Juhlin, C. C., Villabona, L., Larsson, C. & Lui, W.-O., May 2025, In: JID Innovations. 5, 3, 14 p., 100355.

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• Kit-mediated autophagy suppression driven by a viral oncoprotein emerges as a crucial survival mechanism in Merkel cell carcinoma

  Shi, H., Yang, Y., Gao, J., Kumar, S., Xie, H., Chen, Z., Lyu, J., Sihto, H., Koljonen, V., Vega-Rubin-de-Celis, S., Vukojevic, V., Farnebo, F., Björnhagen, V., Höög, A., Juhlin, C. C., Lee, L., Wickström, M., Becker, J. C., Johnsen, J. I. & Larsson, C. & 1 others, Lui, W.-O., 3 Jul 2025, In: Autophagy. 21, 7, p. 1523-1543 21 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Pharmacokinetic profile and in vivo anticancer efficacy of anagrelide administered subcutaneously in rodents

  Toivanen, K., De Sutter, L., Wozniak, A., Wyns, K., Merikoski, N., Salmikangas, S., Duan, J., Maksimow, M., Lahtinen, M., Böhling, T., Schöffski, P. & Sihto, H., 2025, In: Drug Delivery. 32, 1, 11 p., 2463433.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Phosphodiesterase 3 A expression in gastrointestinal stromal tumors

  Sihto, H., Giger, O., Toivanen, K., Salmikangas, S., Vesterinen, T., Sampo, M. & Böhling, T., Nov 2025, In: Virchows Archiv. 487, 5, p. 983-991 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Whole-exome sequencing identifies distinct genomic aberrations in eccrine porocarcinomas and poromas

  Puttonen, M., Almusa, H., Böhling, T., Koljonen, V. & Sihto, H., 13 Feb 2025, In: Orphanet journal of rare diseases. 20, 1, 11 p., 70.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• 2023

  Eccrine Porocarcinoma: Clinical and Histopathological Study of 14 Patients with Special Emphasis on Sentinel Lymph Node Biopsy

  Meriläinen, A.-S., von Willebrand-Bäckman, M. C., Sihto, H. & Koljonen, V., 13 Jul 2023, In: Acta Dermato-Venereologica. 103, 6 p., 11649.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Neurocan expression associates with better survival and viral positivity in Merkel cell carcinoma

  Salmikangas, M., Laaksonen, M., Edgren, H., Salgado, M., Suoranta, A., Mattila, P., Koljonen, V., Böhling, T. & Sihto, H., 5 May 2023, In: PLoS One. 18, 5, 10 p., e0285524.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Patterns of Metastatic Recurrence of Genetically Confirmed Myxoid Liposarcoma

  Homsy, P., Böhling, T., Seitsonen, A., Sampo, M., Tukiainen, E. & Blomqvist, C., 12 Mar 2023, In: Annals of Surgical Oncology. 30, p. 4489–4497 9 p.

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• PDE3A Is a Highly Expressed Therapy Target in Myxoid Liposarcoma: Cancers

  Toivanen, K., Kilpinen, S., Ojala, K., Merikoski, N., Salmikangas, S., Sampo, M., Böhling, T. & Sihto, H., 7 Nov 2023, In: Cancers. 15, 22, 18 p., 5308.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Somatostatin receptor expression in Merkel cell carcinoma: correlation with clinical data

  Fagerstedt, K. W., Vesterinen, T., Leijon, H., Sihto, H., Böhling, T. & Arola, J., 2 Sept 2023, In: Acta Oncologica. 62, 9, p. 1001-1007 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Transcriptomic Analyses Reveal Three Distinct Molecular Subgroups of Merkel Cell Carcinoma with Differing Prognoses

  Sundqvist, B., Kilpinen, S., Böhling, T., Koljonen, V. & Sihto, H., 15 May 2023, In: International Journal of Cancer. 152, 10, p. 2099-2108 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• 2022

  Activation of Oncogenic and Immune-Response Pathways Is Linked to Disease-Specific Survival in Merkel Cell Carcinoma

  Sundqvist, B., Kilpinen, S., Böhling, T., Koljonen, V. & Sihto, H., Aug 2022, In: Cancers. 14, 15, 16 p., 3591.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Merkel cell polyomavirus is a passenger virus in both poroma and porocarcinoma

  Merilainen, A.-S., Sihto, H. & Koljonen, V., Jan 2022, In: Journal of Cutaneous Pathology. 49, 1, p. 49-54 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Oncogenic Merkel Cell Polyomavirus T Antigen Truncating Mutations are Mediated by APOBEC3 Activity in Merkel Cell Carcinoma

  Soikkeli, A., Kyläniemi, M., Sihto, H. & Alinikula, J., 4 Nov 2022, In: Cancer research communications. 2, 11, p. 1344-1354 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• PROX1 transcription factor controls rhabdomyosarcoma growth, stemness, myogenic properties and therapeutic targets

  Gizaw, N. Y., Kallio, P., Punger, T., Gucciardo, E., Haglund, C., Böhling, T., Lehti, K., Sampo, M., Alitalo, K. & Kivelä, R., 6 Dec 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 49, 10 p., e2116220119.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Radiation-associated angiosarcoma of the breast: analysis of diagnostic tools in a registry-based population

  Salminen, S. H., Sampo, M. M., Böhling, T. O., Salo, J., Tarkkanen, M., Blomqvist, C. P. & Hukkinen, K., Jan 2022, In: Acta Radiologica. 63, 1, p. 22-27 6 p., 0284185120980142.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Tensin2 Is a Novel Diagnostic Marker in GIST, Associated with Gastric Location and Non-Metastatic Tumors

  Salmikangas, S., Böhling, T., Merikoski, N., Jagdeo, J., Sampo, M., Vesterinen, T. & Sihto, H., 30 Jun 2022, In: Cancers. 14, 13, 17 p., 3212.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• The Merkel Cell Polyomavirus T-Antigens and IL-33/ST2-IL1RAcP Axis: Possible Role in Merkel Cell Carcinoma

  Rasheed, K., Moens, U., Policastro, B., Johnsen, J. I., Koljonen, V., Sihto, H., Lui, W.-O. & Sveinbjørnsson, B., Apr 2022, In: International Journal of Molecular Sciences. 23, 7, 23 p., 3702.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• UV-induced local immunosuppression in the tumour microenvironment of eccrine porocarcinoma and poroma

  Puttonen, M., Isola, J., Ylinen, O., Böhling, T., Koljonen, V. & Sihto, H., 1 Apr 2022, In: Scientific Reports. 12, 1, 8 p., 5529.

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• Visual Counting and Automated Image-analytic Assessment of Ki-67 and their Prognostic Value in Synovial Sarcoma

  Laurila, R., Böhling, T. O., Blomqvist, C. P., Karlsson, C., Tukiainen, E. J., Repo, J. P. & Sampo, M. M., 31 Jan 2022, In: Cancer Diagnosis & Prognosis. 2, 1, p. 7-14 8 p.

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• 2021

  ALK is frequently phosphorylated in Merkel cell carcinoma and associates with longer survival

  Jaatinen, J., Veija, T., Salmikangas, M., Böhling, T., Sihto, H. & Koljonen, V., 24 May 2021, In: PLoS One. 16, 5, 13 p., 0252099.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• LRIG1 is a positive prognostic marker in Merkel cell carcinoma and Merkel cell carcinoma expresses epithelial stem cell markers

  Sundqvist, B., Sihto, H., von Willebrand, M., Böhling, T. & Koljonen, V., Dec 2021, In: Virchows Archiv. 479, 6, p. 1197-1207 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

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