The cross-talk between epithelium, genome and microbiome in the pathogenesis of airway allergy, asthma and chronic rhinosinusitis

Description

This controlled follow-up study aims at observing candidate alterations in expressed genome, microbiome and molecules in airway epithelium that associate with (1) pollen allergic response (2) moderate-severe asthma and/or chronic rhinosinusitis. By this novel approach, we may increase the understanding of the basic barrier- and microbiome- related mechanisms of inflammatory airway diseases. We try to develop therapeutics an predictive markers for the onset, exacerbations, and progression of chronic inflammatory airway diseases.
Short titleEpithelium and microbiome in inflammatory airway diseases
StatusActive
Effective start/end date01/03/2011 → …

Keywords

  • 3111 Biomedicine
  • Allergology, asthma, rhinology