2-Imidazole as a Substitute for the Electrophilic Group Gives Highly Potent Prolyl Oligopeptidase Inhibitors

Henri T. Pätsi, Tommi P. Kilpeläinen, Samuli Auno, Pyry M. J. Dillemuth, Khaled Arja, Maija K. Lahtela-Kakkonen, Timo T. Myöhänen, Erik A. A. Wallen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalACS Medicinal Chemistry Letters
Volume12
Issue number10
Pages (from-to)1578-1584
Number of pages7
ISSN1948-5875
DOIs
Publication statusPublished - 14 Oct 2021
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Prolyl oligopeptidase
  • triazole
  • imidazole
  • pyrazole
  • alpha-synuclein
  • autophagy
  • ENDOPEPTIDASE
  • KYP-2047
  • 317 Pharmacy
  • 116 Chemical sciences

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