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Vegetative growth and flowering of primocane raspberry 'Ariadne' as affected by prohexadione-calsium treatments

Palonen, P. & Mouhu, K., 2009, In : HortScience. 44, 2, p. 529-531 3 p.

Research output: Contribution to journalArticleScientificpeer-review

Vegetative growth in Rumex acetosella (Polygonacea) originating from different geographic regions

Korpelainen, H., 1993, In : Plant Systematics and Evolution. 188, p. 115-123 9 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-A and VEGF-C in experimental obliterative bronchiolitis

Krebs, R., 2014, Helsinki: [R. Krebs]. 88 p.

Research output: ThesisDoctoral Thesis

VEGF and angiopoietin signaling in tumor angiogenesis and metastasis

Saharinen, P., Eklund, L., Pulkki, K., Bono, P. & Alitalo, K., 2011, In : Trends in Molecular Medicine. 17, 7, p. 347-362 16 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

VEGF and bFGF are highly expressed in intraluminal fibromyxoid lesions in bronchiolitis obliterans organizing pneumonia

Lappi-Blanco, E., Soini, Y., Kinnula, V. & Pääkkö, P., 2002, In : Journal of Pathology. 196, 2, p. 220-227 8 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF and VEGF-C: Specific induction of angiogenesis and lymphangiogenesis in the differentiated avian chorioallantoic membrane

Oh, S. J., Jeltsch, M. M., Birkenhager, R., McCarthy, J. E. G., Weich, H. A., Christ, B., Alitalo, K. & Wilting, J., 1997, In : Developmental Biology. 188, p. 96-109 14 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy

Kim, M., Park, H. J., Seol, J. W., Jang, J. Y., Cho, Y-S., Kim, K. R., Choi, Y., Lydon, J. P., DeMayo, F. J., Shibuya, M., Ferrara, N., Sung, H-K., Nagy, A., Alitalo, K. & Koh, G. Y., Sep 2013, In : EMBO molecular medicine. 5, 9, p. 1415-1430 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications

Robciuc, M. R., Kivela, R., Williams, I. M., de Boer, J. F., van Dijk, T. H., Elamaa, H., Tigistu-Sahle, F., Molotkov, D., Leppanen, V-M., Kakela, R., Eklund, L., Wasserman, D. H., Groen, A. K. & Alitalo, K., 12 Apr 2016, In : Cell Metabolism. 23, 4, p. 712-724 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

VEGF-B binds to VEGFR-1 and regulates plasminogen activator activity in endothelial cells

Olofsson, B., Korpelainen, E., Pepper, M. S., Mandriota, S. J., Kumar, V., Aase, K. A. Y., Gunji, Y., Alitalo, K. & Eriksson, U., 1998, In : Molecular Biology of the Cell. 9, p. 114A-114A 1 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection

Rasanen, M., Degerman, J., Nissinen, T. A., Miinalainen, I., Kerkela, R., Siltanen, A., Backman, J. T., Mervaala, E., Hulmi, J., Kivela, R. & Alitalo, K., 15 Nov 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 46, p. 13144-13149 6 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart

Kivelä, M. R., Bry, M., Robciuc, M. R., Räsänen, M., Taavitsainen, M., Silvola, J. M. U., Saraste, A., Hulmi, J. J., Anisimov, A., Mayranpaa, M. I., Lindeman, J. H., Eklund, L., Hellberg, S., Hlushchuk, R., Zhuang, Z. W., Simons, M., Djonov, V., Knuuti, J., Mervaala, E. & Alitalo, K., Mar 2014, In : EMBO molecular medicine. 6, 3, p. 307-321 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries

Hogan, B. M., Herpers, R., Witte, M., Heloterä, H., Alitalo, K., Duckers, H. J. & Schulte-Merker, S., 2009, In : Development. 136, p. 4001-4009 9 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-C adenovirus gene transfer reduces intima formation in rabbits

Jeltsch, M., Hiltunen, M. O., Laitinen, M., Turunen, M. P., Hartikainen, J., Rissanen, T. T., Laukkanen, J., Niemi, M., Kossila, M., Häkkinen, T. P., Kivelä, A., Enholm, B. C., Mansukoski, H., Turunen, A-M., Alitalo, K. & Ylä-Herttala, S., Jul 2000, 1 ed. 1 p. (Atherosclerosis; vol. 151, no. 1)

Research output: Book/ReportAnthology or special issue

VEGF-C and aortic cardiomyocytes guide coronary artery stem development

Chen, H. I., Poduri, A., Numi, H., Kivela, R., Saharinen, P., McKay, A. S., Raftrey, B., Churko, J., Tian, X., Zhou, B., Wu, J. C., Alitalo, K. & Red-Horse, K., Nov 2014, In : Journal of Clinical Investigation. 124, 11, p. 4899-4914 16 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-C and COX-2 expression in papillary thyroid cancer

Siironen, P., Ristimäki, A., Narko, K., Nordling, S., Louhimo, J., Andersson, S., Haapiainen, R. & Haglund, C., 2006, In : Endocrine - Related Cancer. 13, p. 465-473 9 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-C and VEGF-C156S in the pro-lymphangiogenic growth factor therapy of lymphedema: a large animal study

Visuri, M. T., Honkonen, K. M., Hartiala, P., Tervala, T. V., Halonen, P. J., Junkkari, H., Knuutinen, N., Yla-Herttuala, S., Alitalo, K. K. & Saarikko, A., Jul 2015, In : Angiogenesis. 18, 3, p. 313-326 14 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-C and VEGF-D Blockade Inhibits Inflammatory Skin Carcinogenesis

Alitalo, A. K., Proulx, S. T., Karaman, S., Aebischer, D., Martino, S., Jost, M., Schneider, N., Bry, M. & Detmar, M., 15 Jul 2013, In : Cancer Research. 73, 14, p. 4212-4221 10 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues

Partanen, T. A., Arola, J., Saaristo, A., Jussila, L., Ora, A., Miettinen, M., Stacker, S. A., Achen, M. G. & Alitalo, K., 2000, In : FASEB Journal. 14, p. 2087-2096 10 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours

Song, E., Mao, T., Dong, H., Boisserand, L. S. B., Antila, S., Bosenberg, M., Alitalo, K., Thomas, J-L. & Iwasaki, A., 30 Jan 2020, In : Nature. 577, 7792, p. 689-+ 21 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-C induced angiogenesis preferentially occurs at a distance from lymphangiogenesis

Benest, A. V., Harper, S. J., Herttuala, S. Y., Alitalo, K. & Bates, D. O., 2008, In : Cardiovascular Research. 78, p. 315-323 9 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites

Hirakawa, S., Brown, L. F., Kodama, S., Paavonen, K., Alitalo, K. & Detmar, M., 2007, In : Blood. 109, 3, p. 1010-1017 8 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-C induced lymphangiogenesis is associated with lymph node metastasis in orthotopic MCF-7 tumors

Mattila, M. M. T., Ruohola, J. K., Karpanen, T., Jackson, D. G., Alitalo, K. & Harkonen, P. L., 2002, In : International Journal of Cancer. 98, p. 946-951 6 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain

Le Bras, B., Barallobre, M-J., Homman-Ludiye, J., Ny, A., Wyns, S., Tammela, T., Haiko, P., Kärkkäinen, M., Yuan, L., Muriel, M-P., Chatzopoulou, E., Breant, C., Zalc, B., Carmeliet, P., Alitalo, K., Eichmann, A. & Thomas, J-L., 2006, In : Nature Neuroscience. 9, 3, p. 340-348 9 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-C is required for intestinal lymphatic vessel maintenance and lipid absorption

Nurmi, H., Saharinen, P., Zarkada, G., Zheng, W., Robciuc, M. R. & Alitalo, K., Nov 2015, In : EMBO molecular medicine. 7, 11, p. 1418-1425 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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Vegfc is required for vascular development and endoderm morphogenesis in zebrafish

Ober, E. A., Olofsson, B., Makinen, T., Jin, S. W., Shoji, W., Koh, G. Y., Alitalo, K. & Stainier, D. Y. R., 2004, In : EMBO Reports. 5, p. 78-84 7 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-C promotes the development of lymphatics in bone and bone loss

Hominickn, D., Silva, A., Khurana, N., Liu, Y., Dechow, P. C., Feng, J. Q., Pytowski, B., Rutkowski, J. M., Alitalo, K. & Dellinger, M. T., 5 Apr 2018, In : eLife. 7, 22 p., 34323.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development

Kukk, E., Lymboussaki, A., Taira, S., Kaipainen, A., Jeltsch, M., Joukov, V. & Alitalo, K., 1996, In : Sustainable Development. 122, p. 3829-3837 9 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGFC Reduces Glomerular Albumin Permeability and Protects Against Alterations in VEGF Receptor Expression in Diabetic Nephropathy

Onions, K. L., Gamez, M., Buckner, N. R., Baker, S. L., Betteridge, K. B., Desideri, S., Dallyn, B. P., Ramnath, R. D., Neal, C. R., Farmer, L. K., Mathieson, P. W., Gnudi, L., Alitalo, K., Bates, D. O., Salmon, A. H. J., Welsh, G. I., Satchell, S. C. & Foster, R. R., Jan 2019, In : Diabetes. 68, 1, p. 172-187 16 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-C signaling pathways through VEGFR-2 and VEGFR-3 in vasculoangiogenesis and hematopoiesis

Hamada, K., Oike, Y., Takakura, N., Ito, Y., Jussila, L., Dumont, D. J., Alitalo, K. & Suda, T., 2000, In : Blood. 96, p. 3793-3800 8 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-D: a modifier of embryonic lymphangiogenesis

Kärpänen, T. & Alitalo, K., 2008, In : Blood. 112, 5, p. 1547-1548 2 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-D in association with VEGFR-3 promotes nodal metastasis in human invasive lobular breast cancer

van Iterson, V., Leidenius, M., Smitten, K. V., Bono, P. & Heikkilä, P., 2007, In : American Journal of Clinical Pathology. 128, 5, p. 759-766 8 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses

Rissanen, T. T., Markkanen, J. E., Gruchala, M., Heikura, T., Puranen, A., Kettunen, M. I., Kholova, I., Kauppinen, R. A., Achen, M. G., Stacker, S. A., Alitalo, K. & Yla-Herttuala, S., 2003, In : Circulation Research. 92, p. 1098-1106 9 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF gene variability and type 1 diabetes: evidence for a protective role

Del Bo, R., Scarlato, M., Ghezzi, S., Maestroni, A., Sjölind, L., Forsblom, C., Wessman, M., Groop, P-H., Comi, G. P., Bresolin, N., Luzi, L. & Zerbini, G., 2006, In : Immunogenetics. 58, p. 107-112 6 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

Gerhardt, H., Golding, M., Fruttiger, M., Ruhrberg, C., Lundkvist, A., Abramsson, A., Jeltsch, M., Mitchell, C., Alitalo, K., Shima, D. & Betsholtz, C., 2003, In : Journal of Cell Biology. 161, p. 1163-1177 15 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF in 105 pheochromocytomas: enhanced expression correlates with malignant outcome

Salmenkivi, K., Heikkilä, P., Liu, J. Q., Haglund, C. & Arola, J., 2003, In : APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. 111, 4, p. 458-464 7 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF Mediates Commissural Axon Chemoattraction through Its Receptor Flk1

de Almodovar, C. R., Fabre, P. J., Knevels, E., Coulon, C., Segura, I., Haddick, P. C. G., Aerts, L., Delattin, N., Strasser, G., Oh, W-J., Lange, C., Vinckier, S., Haigh, J., Fouquet, C., Gu, C., Alitalo, K., Castellani, V., Tessier-Lavigne, M., Chedotal, A., Charron, F. & 1 others, Carmeliet, P., 2011, In : Neuron. 70, 5, p. 966-978 13 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF overexpression improves mesenchymal stem cell sheet transplantation therapy for acute myocardial infarction

Augustin, M., Mahar, M. A. A., Lakkisto, P., Tikkanen, I., Vento, A., Pätilä, T. & Harjula, A., Sep 2013, In : Journal of Tissue Engineering and Regenerative Medicine. 7, 9, p. 742-750 9 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGF Pathways in the Lymphatics of Healthy and Diseased Heart

Dashkevich, A., Hagl, C., Beyersdorf, F., Nykänen, A. & Lemstrom, K. B., Jan 2016, In : Microcirculation. 23, 1, p. 5-14 10 p.

Research output: Contribution to journalReview ArticleScientificpeer-review

VEGFR-1 and -2 regulate inflammation, myocardial angiogenesis, and arteriosclerosis in chronically rejecting cardiac allografts

Raisky, O., Nykänen, A. I., Krebs, R., Hollmen, M., Keränen, M. A. I., Tikkanen, J. M., Sihvola, R., Alhonen, L., Salven, P., Wu, Y., Hicklin, D. J., Alitalo, K., Koskinen, P. K. & Lemström, K. B., 2007, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 27, p. 819-825 7 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGFR2 but not VEGFR3 governs integrity and remodeling of thyroid angiofollicular unit in normal state and during goitrogenesis

Jang, J. Y., Choi, S. Y., Park, I., Park, D. Y., Choe, K., Kim, P., Kim, Y. K., Lee, B-J., Hirashima, M., Kubota, Y., Park, J-W., Cheng, S-Y., Nagy, A., Park, Y. J., Alitalo, K., Shong, M. & Koh, G. Y., Jun 2017, In : EMBO molecular medicine. 9, 6, p. 750-769 20 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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VEGFR-2-specific forms of VEGF-D and VEGF-C and uses thereof

Alitalo, K. K., Jeltsch, M. M., Leppänen, V-M., Aho, K. K., Anisimov, A. & Tvorogov, D., 5 Jul 2012, WIPO, Patent No. WO2012/088563, 2 Jul 2012, Priority date 24 Nov 2010, Priority No. 61/458,517 (US)

Research output: Patent

File

VEGFR-3 and CD133 identify a population of CD34(+) lymphatic/vascular endothelial precursor cells

Salven, P., Mustjoki, S., Alitalo, R., Alitalo, K. & Rafii, S., 2003, In : Blood. 101, p. 168-172 5 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGFR3 and CD31 as Prognostic Factors in Renal Cell Cancer

Virman, J., Bono, P., Luukkaala, T., Sunela, K., Kujala, P. & Kellokumpu-Lehtinen, P-L., Feb 2015, In : Anticancer Research. 35, 2, p. 921-927 7 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGFR-3 and its ligand VEGF-C are associated with angiogenesis in breast cancer

Valtola, R., Salven, P., Heikkila, P., Taipale, J., Joensuu, H., Rehn, M., Pihlajaniemi, T., Weich, H., deWaal, R. & Alitalo, K., 1999, In : The American Journal of Pathology. 154, p. 1381-1390 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Vegfr3 and notch signaling in angiogenesis

Zarkada, G., 2014, Helsinki: University of Helsinki. 90 p.

Research output: ThesisDoctoral ThesisCollection of Articles

VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling

Tammela, T., Zarkada, G., Nurmi, H., Jakobsson, L., Heinolainen, K., Tvorogov, D., Zheng, W., Franco, C. A., Murtomaki, A., Aranda, E., Miura, N., Yla-Herttuala, S., Fruttiger, M., Makinen, T., Eichmann, A., Pollard, J. W., Gerhardt, H. & Alitalo, K., 2011, In : Nature Cell Biology. 13, 10, p. 1202-1213 23 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGFR3 does not sustain retinal angiogenesis without VEGFR2

Zarkada, G., Heinolainen, K., Makinen, T., Kubota, Y. & Alitalo, K., 20 Jan 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 3, p. 761-766 6 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGFR-3 expression is restricted to blood and lymphatic vessels in solid tumors: [correspondence]

Petrova, T., Bono, P., Holnthoner, W., Chesnes, J., Pytowski, B., Sihto, H., Laakkonen, P., Heikkilä, P., Joensuu, H. & Alitalo, K., 2008, In : Cancer Cell. 13, 6, p. 554-556 3 p.

Research output: Contribution to journalArticleScientificpeer-review

VEGFR-3 fusion proteins

Alitalo, K. K. & Jeltsch, M. M., 9 Sep 2008, US Patent and Trademark Office, Patent No. US 7,422,741 B2, 9 Sep 2008, Priority date 5 Mar 2004, Priority No. 60/550,907

Research output: Patent

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VEGFR3 gene structure, regulatory region, and sequence polymorphisms

Iljin, K., Karkkainen, M. J., Lawrence, E. C., Kimak, M. A., Uutela, M., Taipale, J., Pajusola, K., Alhonen, L., Halmekyto, M., Finegold, D. N., Ferrell, R. E. & Alitalo, K., 2001, In : FASEB Journal. 15, p. 1028-1036 9 p.

Research output: Contribution to journalArticleScientificpeer-review