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• Finländsk neuropatologi fram till 2020-talet

  Tynninen, O., Paetau, A. & Myllykangas, L., 2021, In: Finska Läkaresällskapets Handlingar. 181, 1, p. 84-88 5 p.

  Research output: Contribution to journal › Article › Professional

  Open Access

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• A familial frontotemporal dementia associated with C9orf72 repeat expansion and dysplastic gangliocytoma

  Ferrari, R., Kero, M., Mok, K., Paetau, A., Tienari, P. J., Tynninen, O., Hardy, J., Momeni, P., Verkkoniemi-Ahola, A. & Myllykangas, L., 1 Feb 2014, In: Neurobiology of Aging. 35, 2, 4 p., 444.e11.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Neuropathologic features of four autopsied COVID-19 patients

  Kantonen, J., Mahzabin, S., Mäyränpää, M., Tynninen, O., Paetau, A., Andersson, N., Sajantila, A., Vapalahti, O., Carpen, O., Kekäläinen, E., Kantele, A. & Myllykangas, L., 28 Aug 2020, (E-pub ahead of print) In: Brain Pathology. 5 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Pahanlaatuisuusaste ei yksin riitä - molekyylitutkimukset tarkentavat glioomien diagnostiikkaa

  Tynninen, O., Paetau, A., Haapasalo, H. & Kytölä, S., 2020, In: Duodecim. 136, 10, p. 1202-1208 7 p.

  Research output: Contribution to journal › Review Article › Scientific › peer-review

  Open Access

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• Expression of KIT Receptor Tyrosine Kinase in Endothelial Cells of Juvenile Brain Tumors

  Puputti, M., Tynninen, O., Pernila, P., Salmi, M., Jalkanen, S., Paetau, A., Sihto, H. & Joensuu, H., 2010, In: Brain Pathology. 20, p. 763-770 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo

  Cullen, V., Lindfors, M., Ng, J., Paetau, A., Swinton, E., Kolodziej, P., Boston, H., Saftig, P., Woulfe, J., Feany, M. B., Myllykangas, L., Schlossmacher, M. G. & Tyynelä, J., 2009, In: Molecular brain.

  Research output: Contribution to journal › Article › Scientific › peer-review

• The Hypermethylation of the O-6-methylguanine-DNA Methyltransferase Gene Promoter in Gliomas-Correlation with Array Comparative Genome Hybridization Results and IDH1 Mutation

  Tuononen, K., Tynninen, O., Sarhadi, V. K., Tyybäkinoja, A., Lindlof, M., Antikainen, M., Napankangas, J., Hirvonen, A., Paetau, A., Knuutila, S. & Mäenpää, H. O., 2012, In: Genes, Chromosomes & Cancer. 51, 1, p. 20-29 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Capillary Amyloid-beta Protein Deposition in a Population-Based Study (Vantaa 85+)

  Makela, M., Paetau, A., Polvikoski, T., Myllykangas, L. & Tanskanen, M., 2015, In: Journal of Alzheimer's Disease. 49, 1, p. 149-157 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Neuropathologic and genetic determinants of neurodegenerative proteinopathies: special emphasis on hippocampal sclerosis and TDP-43 pathology

  Kero, M., 2019, HELSINKI UNIVERSITY. 106 p.

  Research output: Thesis › Doctoral Thesis › Collection of Articles

  Open Access

• alpha-Synuclein pathology in the spinal cord autonomic nuclei associates with alpha-synuclein pathology in the brain: a population-based Vantaa 85+study

  Oinas, M., Paetau, A., Myllykangas, L., Notkola, I-L., Kalimo, H. & Polvikoski, T., 2010, In: Acta Neuropathologica. 119, 6, p. 715-722 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Molecular genetic analysis of the REST/NRSF gene in nervous system tumors

  Blom, T., Tynninen, O., Puputti, M., Halonen, M., Paetau, A., Haapasalo, H., Tanner, M. & Nupponen, N. N., 2006, In: Acta Neuropathologica. 112, 4, p. 483-490 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Hippocampal Sclerosis in the Oldest Old: A Finnish Population-Based Study

  Kero, M., Raunio, A., Polvikoski, T., Tienari, P. J., Paetau, A. & Myllykangas, L., 2018, In: Journal of Alzheimer's Disease. 63, 1, p. 263-272 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Senile systemic amyloidosis affects 25% of the very aged and associates with genetic variation in alpha2-macroglobulin and tau: a population-based autopsy study

  Tanskanen, M., Peuralinna, T., Polvikoski, T., Notkola, I-L., Sulkava, R., Hardy, J., Singleton, A., Kiuru-Enari, S., Paetau, A., Tienari, P. J. & Myllykangas, L., 2008, In: Annals of Medicine. 40, 3, p. 232-239 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Amplification of KIT, PDGFRA, VEGFR2, and EGFR in gliomas

  Puputti, M., Tynninen, O., Sihto, H., Blom, T., Mäenpää, H., Isola, J., Paetau, A., Joensuu, H., Nupponen, N. & Mäenpää, H., 2006, In: Molecular Cancer Research. 4, 12, p. 927-934 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Neurofibrillary tau pathology modulated by genetic variation of [alpha]-synuclein

  Peuralinna, T., Oinas, M., Polvikoski, T., Paetau, A., Sulkava, R., Niinistö, L., Kalimo, H., Hernandez, D., Hardy, J., Singleton, A., Tienari, P. J. & Myllykangas, L., 2008, In: Annals of Neurology. 64, 3, p. 348-352 5 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Neuropathologic Findings of Dementia with Lewy Bodies (DLB) in a Population-based Vantaa 85+Study

  Oinas, M., Polvikoski, T., Sulkava, R., Myllykangas, L., Juva, K., Notkola, I-L., Rastas, S., Niinisto, L., Kalimo, H. & Paetau, A., 2009, In: Journal of Alzheimer's Disease. 18, p. 677-689 13 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Amygdala alpha-Synuclein Pathology in the Population-Based Vantaa 85+Study

  Raunio, A. K., Myllykangas, L., Kero, M., Polvikoski, T., Paetau, A. & Oinas, M., 2017, In: Journal of Alzheimer's Disease. 58, 3, p. 669-674 6 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• Alpha-synuclein pathology of olfactory bulbs/peduncles in the Vantaa85+cohort exhibit two divergent patterns: a population-based study

  Kok, E. H., Savola, S., Raunio, A., Oinas, M., Tuimala, J., Polvikoski, T., Kero, M., Kaivola, K., Tienari, P. J., Paetau, A. & Myllykangas, L., Oct 2021, In: Acta Neuropathologica. 142, 4, p. 777-780 4 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Matrix metalloproteinase-19 expressed in cerebral amyloid angiopathy

  Tanskanen, M., Myllykangas, L. T., Saarialho-Kere, U. & Paetau, A., 2011, In: Amyloid. 18, 1, p. 3-9 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Alzheimer risk loci and associated neuropathology in a population-based study (Vantaa 85+)

  Mäkelä, M., Kaivola, K., Valori, M., Paetau, A., Polvikoski, T., Singleton, A. B., Traynor, B. J., Stone, D. J., Peuralinna, T., Tienari, P. J., Tanskanen, M. & Myllykangas, L., Feb 2018, In: Neurology Genetics. UNSP e211 .

  Research output: Contribution to journal › Article › Scientific › peer-review

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• Lewy-related pathology exhibits two anatomically and genetically distinct progression patterns: a population-based study of Finns aged 85+

  Raunio, A., Kaivola, K., Tuimala, J., Kero, M., Oinas, M., Polvikoski, T., Paetau, A., Tienari, P. J. & Myllykangas, L., Nov 2019, In: Acta Neuropathologica. 138, 5, p. 771-782 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

• A novel alpha-synuclein mutation A53E associated with atypical multiple system atrophy and Parkinson's disease-type pathology

  Pasanen, P., Myllykangas, L., Siitonen, M., Raunio, A., Kaakkola, S., Lyytinen, J., Tienari, P. J., Poyhonen, M. & Paetau, A., 1 Sep 2014, In: Neurobiology of Aging. 35, 9

  Research output: Contribution to journal › Article › Scientific › peer-review

• A Novel Loss-of-Function GRN Mutation p.(Tyr229*): Clinical and Neuropathological Features

  Kuuluvainen, L., Pöyhönen, M., Pasanen, P., Siitonen, M., Rummukainen, J., Tienari, P. J., Paetau, A. & Myllykangas, L., 2017, In: Journal of Alzheimer's Disease. 55, 3, p. 1167-1174 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Population-based analysis of pathological correlates of dementia in the oldest old

  Tanskanen, M., Mäkelä, M., Notkola, I-L., Myllykangas, L., Rastas, S., Oinas, M., Lindsberg, P. J., Polvikoski, T., Tienari, P. J. & Paetau, A., Mar 2017, In: Annals of Clinical and Translational Neurology. 4, 3, p. 154-165 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Primary age-related tauopathy in a Finnish population-based study of the oldest old (Vantaa 85+)

  Savola, S., Kaivola, K., Raunio, A., Kero, M., Mäkelä, M., Pärn, K., Palta, P., Tanskanen, M., Tuimala, J., Polvikoski, T., Tienari, P. J., Paetau, A. & Myllykangas, L., Apr 2022, In: Neuropathology and Applied Neurobiology. 48, 3, 12 p., 12788.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Genetics of dementia in a Finnish cohort

  Pasanen, P., Myllykangas, L., Pöyhönen, M., Kiviharju, A., Siitonen, M., Hardy, J., Bras, J., Paetau, A., Tienari, P. J., Guerreiro, R. & Verkkoniemi-Ahola, A., Jun 2018, In: European Journal of Human Genetics. 26, 6, p. 827-837 11 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• APOE and A beta PP Gene Variation in Cortical and Cerebrovascular Amyloid-beta Pathology and Alzheimer's Disease: A Population-Based Analysis

  Peuralinna, T., Tanskanen, M., Mäkelä, M., Polvikoski, T., Paetau, A., Kalimo, H., Sulkava, R., Hardy, J., Lai, S-L., Arepalli, S., Hernandez, D., Traynor, B. J., Singleton, A., Tienari, P. J. & Myllykangas, L., 2011, In: Journal of Alzheimer's Disease. 26, 2, p. 377-385 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Putative risk alleles for LATE-NC with hippocampal sclerosis in population-representative autopsy cohorts

  EClipSE Collaboration, Hokkanen, S. R. K., Kero, M., Kaivola, K., Hunter, S., Keage, H. A. D., Kiviharju, A., Raunio, A., Tienari, P. J., Paetau, A., Matthews, F. E., Fleming, J., Graff, C., Polvikoski, T. M., Myllykangas, L. & Brayne, C., Mar 2020, In: Brain Pathology. 30, 2, p. 364-372 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Fatal Tick-Borne Encephalitis Virus Infections Caused by Siberian and European Subtypes, Finland, 2015

  Kuivanen, S., Smura, T., Rantanen, K., Kämppi, L., Kantonen, J., Kero, M., Jaaskelainen, A., Jaaskelainen, A. J., Sane, J., Myllykangas, L., Paetau, A. & Vapalahti, O., May 2018, In: Emerging Infectious Diseases. 24, 5, p. 946-948 3 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study

  Hooshmand, B., Polvikoski, T., Kivipelto, M., Tanskanen, M., Myllykangas, L., Erkinjuntti, T., Mäkelä, M., Oinas, M., Paetau, A., Scheltens, P., van Straaten, E. C. W., Sulkava, R. & Solomon, A., Sep 2013, In: Brain : a journal of neurology. 136, p. 2707-2716 10 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Amyloid precursor protein (APP) A673T mutation in the elderly Finnish population.

  Kero, M., Paetau, A., Polvikoski, T., Tanskanen, M., Sulkava, R., Jansson, L., Myllykangas, L. T. & Tienari, P., 2013, In: Neurobiology of Aging. 34, 5, p. 1518.e1-1518.e3 3 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Stem cell protein BMI-1 is an independent marker for poor prognosis in oligodendroglial tumours

  Häyry, V., Tynninen, O., Haapasalo, H. K., Wölfer, J., Paulus, W., Hasselblatt, M., Sariola, H., Paetau, A., Sarna, S., Niemelä, M., Wartiovaara, K. & Nupponen, N. N., 2008, In: Neuropathology and Applied Neurobiology. 34, 5, p. 555-563 9 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Alzheimer disease PS-1 exon 9 deletion defined

  Prihar, G., Verkkoniemi, A., Perez-Tur, J., Crook, R., Lincoln, S., Moulden, H., Somer, M., Paetau, A., Kalimo, H., Grover, A., Myllykangas, L., Hutton, M., Hardy, J. & Haltia, M., 1999, In: Nature Medicine. 5, p. 1090-1090 1 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+cohort study

  Hall, A., Pekkala, T., Polvikoski, T., van Gils, M., Kivipelto, M., Lötjönen, J., Mattila, J., Kero, M., Myllykangas, L., Mäkelä, M., Oinas, M., Paetau, A., Soininen, H., Tanskanen, M. & Solomon, A., 22 Jan 2019, In: Alzheimer's research & therapy. 11, 12 p., 11.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Suomalaisen ALS:n salat julki

  Laaksovirta, H., Myllykangas, L. T., Kalimo, H. O., Paetau, A., Remes, AM., Peuralinna, T., Jansson, L. C., Isoviita, V-M., Kaivorinne, L., Hölttä-Vuori, M., Ikonen, E. M., Sulkava, R. & Tienari, P., 2011, In: Duodecim. 127, 19, p. 2098 1 p.

  Research output: Contribution to journal › Article › Professional

• Oligogenic basis of sporadic ALS The example of SOD1 p.Ala90Val mutation

  Kuuluvainen, L., Kaivola, K., Mönkäre, S., Laaksovirta, H., Jokela, M., Udd, B., Valori, M., Pasanen, P., Paetau, A., Traynor, B. J., Stone, D. J., Schleutker, J., Pöyhönen, M., Tienari, P. J. & Myllykangas, L., Jun 2019, In: Neurology Genetics. 5, 3, 6 p., 335.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Neuropathological and genetic determinants of dementia : a prospective and population-based study on very elderly finns

  Mäkelä, M., 2018, Helsinki: [M. Mäkelä]. 122 p.

  Research output: Thesis › Doctoral Thesis › Collection of Articles

• SNCA mutation p.Ala53Glu is derived from a common founder in the Finnish population

  Pasanen, P., Palin, E., Pohjolan-Pirhonen, R., Pöyhönen, M., Rinne, J. O., Päivärinta, M., Martikainen, M. H., Kaasinen, V., Hietala, M., Gardberg, M., Saukkonen, A. M., Eerola-Rautio, J., Kaakkola, S., Lyytinen, J., Tienari, P., Paetau, A., Suomalainen, A. & Myllykangas, L., 2017, In: Neurobiology of Aging. 50, 4 p., 168.e5 .

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Prevalence and severity of cerebral amyloid angiopathy: a population-based study on very elderly Finns (Vantaa 85+)

  Tanskanen, M., Mäkelä, M., Myllykangas, L., Notkola, I. -L., Polvikoski, T., Sulkava, R., Kalimo, H. & Paetau, A., 2012, In: Neuropathology and Applied Neurobiology. 38, 4, p. 329-336 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Senile systemic amyloidosis affects 25% of the very aged and associates with genetic variation in alpha2-macroglobulin and tau: a population-based autopsy study. Ann Med 2008; 40: 232-9

  Tanskanen, M., Peuralinna, T., Polvikoski, T., Notkola, I-L., Hardy, J., Singleton, A., Kiuru-Enari, S. M. K., Paetau, A., Tienari, P. & Myllykangas, L. T., 2008, In: Annals of Medicine. 40, p. 232-9

  Research output: Contribution to journal › Article › Scientific › peer-review

• Genome-wide association study of neocortical Lewy-related pathology

  Peuralinna, T., Myllykangas, L., Oinas, M., Nails, M. A., Keage, H. A. D., Isoviita, V-M., Valori, M. V. P., Polvikoski, T., Paetau, A., Sulkava, R., Ince, P. G., Zaccai, J., Brayne, C., Traynor, B. J., Hardy, J., Singleton, A. B. & Tienari, P. J., 18 Aug 2015, In: Annals of Clinical and Translational Neurology. 2, 9, p. 920–931 12 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• CAIDE Dementia Risk Score, Alzheimer and cerebrovascular pathology: a population-based autopsy study

  Hooshmand, B., Polvikoski, T., Kivipelto, M., Myllykangas, L., Mäkelä, M., Tanskanen, M., Oinas, M., Paetau, A. & Solomon, A., Jun 2018, In: Journal of internal medicine. 283, 6, p. 597-603 7 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

  Open Access

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• Progression of diffuse gliomas: from the first diagnosis to recurrence

  Tynninen, O., 2011, Helsinki: University of Helsinki. 86 p.

  Research output: Thesis › Doctoral Thesis › Collection of Articles

• Relationships Between White Matter Hyperintensities, Cerebral Amyloid Angiopathy and Dementia in a Population-based Sample of the Oldest Old

  Tanskanen, M., Kalaria, R. N., Notkola, I. -L., Makela, M., Polvikoski, T., Myllykangas, L., Sulkava, R., Kalimo, H., Paetau, A., Scheltens, P., Barkhof, F., van Straaten, E. C. W. & Erkinjuntti, T., Dec 2013, In: Current Alzheimer research. 10, 10, p. 1090-1097 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Prionitaudit

  Paetau, A. & Verkkoniemi-Ahola, A., 2015, Muistisairaudet. Erkinjuntti, T., Remes, A., Rinne, J. & Soininen, H. (eds.). 2. uud. p. ed. Helsinki: Kustannus Oy Duodecim, p. 181-186 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Labyrinthine pathology in a deaf patient with infantile onset spinocerebellar ataxia (IOSCA)

  Johnsson, L-G., Felix, H., Paetau, A. & Lönnqvist, T., 1997, Progress in Human Auditory and Vestibular Histopathology. Iurato, S. & Veldman, J. E. (eds.). Kugler Pubns B V, p. 103-108 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Onko neurobiologinen perustutkimus tuonut uusia näkökulmia kehitysvammaisuuden etiologiaan?

  Paetau, A. & Soinila, S., 2006, In: Duodecim. 122, p. 1903-1906 4 p.

  Research output: Contribution to journal › Article › Scientific › peer-review

• Infantile-Onset Spinocerebellar Ataxia

  Lönnqvist, T., Paetau, A., Pihko, H. & Nikali, K., 2000, Handbook of Ataxia Disorders. Klockgether, T. (ed.). 1. p. ed. New York : CRC press, p. 293-309 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Professional

• Experimental models of muscle disease

  Suomalainen Wartiovaara, A., Peltola, K. E., Paetau, A. & Wallgren-Pettersson, C., 2006, Methods and Techniques in Animal Reserach: Handbook of experimental neurology. Tatlisumak, T. & Fischer, M. (eds.). Cambridge University Press

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › Scientific

• Aiemmin terveen naisen raju endokardiitti: [kliinis-patologinen kokousselostus]

  Sinisalo, J., Pohjola-Sintonen, S., Tynninen, O. & Silvennoinen, H., 2009, In: Duodecim. 125, 3, p. 289-296 8 p.

  Research output: Contribution to journal › Article › Scientific › peer-review