A loss-of-function variant in OSBPL1A predisposes to low plasma HDL cholesterol levels and impaired cholesterol efflux capacity

Mahdi M. Motazacker, Juho Pirhonen, Julian C. van Capelleveen, Marion Weber-Boyvat, Jan Albert Kuivenhoven, Saundarya Shah, G. Kees Hovingh, Jari Metso, Shiqian Li, Elina Ikonen, Matti Jauhiainen, Geesje M. Dallinga-Thie, Vesa M. Olkkonen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalAtherosclerosis
Volume249
Pages (from-to)140-147
Number of pages8
ISSN0021-9150
DOIs
Publication statusPublished - Jun 2016
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Cholesterol efflux
  • High-density lipoprotein
  • Oxysterol-binding protein
  • OSBPL1A
  • Rare variant
  • OXYSTEROL-BINDING-PROTEIN
  • HIGH-DENSITY-LIPOPROTEIN
  • PHOSPHOLIPID TRANSFER PROTEIN
  • CORONARY-HEART-DISEASE
  • CARDIOVASCULAR-DISEASE
  • SENSOR ORP1L
  • HUMANS
  • SERUM
  • RAB7-RILP-P150(GLUED)
  • LOCALIZATION
  • 3121 Internal medicine

Cite this

Motazacker, Mahdi M. ; Pirhonen, Juho ; van Capelleveen, Julian C. ; Weber-Boyvat, Marion ; Kuivenhoven, Jan Albert ; Shah, Saundarya ; Hovingh, G. Kees ; Metso, Jari ; Li, Shiqian ; Ikonen, Elina ; Jauhiainen, Matti ; Dallinga-Thie, Geesje M. ; Olkkonen, Vesa M. / A loss-of-function variant in OSBPL1A predisposes to low plasma HDL cholesterol levels and impaired cholesterol efflux capacity. In: Atherosclerosis. 2016 ; Vol. 249. pp. 140-147.
@article{ae369e18330a4ef181b9d97d0bc32676,
title = "A loss-of-function variant in OSBPL1A predisposes to low plasma HDL cholesterol levels and impaired cholesterol efflux capacity",
keywords = "Cholesterol efflux, High-density lipoprotein, Oxysterol-binding protein, OSBPL1A, Rare variant, OXYSTEROL-BINDING-PROTEIN, HIGH-DENSITY-LIPOPROTEIN, PHOSPHOLIPID TRANSFER PROTEIN, CORONARY-HEART-DISEASE, CARDIOVASCULAR-DISEASE, SENSOR ORP1L, HUMANS, SERUM, RAB7-RILP-P150(GLUED), LOCALIZATION, 3121 Internal medicine",
author = "Motazacker, {Mahdi M.} and Juho Pirhonen and {van Capelleveen}, {Julian C.} and Marion Weber-Boyvat and Kuivenhoven, {Jan Albert} and Saundarya Shah and Hovingh, {G. Kees} and Jari Metso and Shiqian Li and Elina Ikonen and Matti Jauhiainen and Dallinga-Thie, {Geesje M.} and Olkkonen, {Vesa M.}",
year = "2016",
month = "6",
doi = "10.1016/j.atherosclerosis.2016.04.005",
language = "English",
volume = "249",
pages = "140--147",
journal = "Atherosclerosis",
issn = "0021-9150",
publisher = "ELSEVIER IRELAND LTD",

}

Motazacker, MM, Pirhonen, J, van Capelleveen, JC, Weber-Boyvat, M, Kuivenhoven, JA, Shah, S, Hovingh, GK, Metso, J, Li, S, Ikonen, E, Jauhiainen, M, Dallinga-Thie, GM & Olkkonen, VM 2016, 'A loss-of-function variant in OSBPL1A predisposes to low plasma HDL cholesterol levels and impaired cholesterol efflux capacity' Atherosclerosis, vol. 249, pp. 140-147. https://doi.org/10.1016/j.atherosclerosis.2016.04.005

A loss-of-function variant in OSBPL1A predisposes to low plasma HDL cholesterol levels and impaired cholesterol efflux capacity. / Motazacker, Mahdi M.; Pirhonen, Juho; van Capelleveen, Julian C.; Weber-Boyvat, Marion; Kuivenhoven, Jan Albert; Shah, Saundarya; Hovingh, G. Kees; Metso, Jari; Li, Shiqian; Ikonen, Elina; Jauhiainen, Matti; Dallinga-Thie, Geesje M.; Olkkonen, Vesa M.

In: Atherosclerosis, Vol. 249, 06.2016, p. 140-147.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - A loss-of-function variant in OSBPL1A predisposes to low plasma HDL cholesterol levels and impaired cholesterol efflux capacity

AU - Motazacker, Mahdi M.

AU - Pirhonen, Juho

AU - van Capelleveen, Julian C.

AU - Weber-Boyvat, Marion

AU - Kuivenhoven, Jan Albert

AU - Shah, Saundarya

AU - Hovingh, G. Kees

AU - Metso, Jari

AU - Li, Shiqian

AU - Ikonen, Elina

AU - Jauhiainen, Matti

AU - Dallinga-Thie, Geesje M.

AU - Olkkonen, Vesa M.

PY - 2016/6

Y1 - 2016/6

KW - Cholesterol efflux

KW - High-density lipoprotein

KW - Oxysterol-binding protein

KW - OSBPL1A

KW - Rare variant

KW - OXYSTEROL-BINDING-PROTEIN

KW - HIGH-DENSITY-LIPOPROTEIN

KW - PHOSPHOLIPID TRANSFER PROTEIN

KW - CORONARY-HEART-DISEASE

KW - CARDIOVASCULAR-DISEASE

KW - SENSOR ORP1L

KW - HUMANS

KW - SERUM

KW - RAB7-RILP-P150(GLUED)

KW - LOCALIZATION

KW - 3121 Internal medicine

U2 - 10.1016/j.atherosclerosis.2016.04.005

DO - 10.1016/j.atherosclerosis.2016.04.005

M3 - Article

VL - 249

SP - 140

EP - 147

JO - Atherosclerosis

JF - Atherosclerosis

SN - 0021-9150

ER -