A microfluidic oxygen sink to create a targeted cellular hypoxic microenvironment under ambient atmospheric conditions

Samineh Barmaki; Ville Jokinen; Daniela Obermaier; Daria Blokhina; Matti Korhonen; Robin H. A. Ras; Jyrki Vuola; Sami Franssila; Esko Kankuri

doi:10.1016/j.actbio.2018.04.007

A microfluidic oxygen sink to create a targeted cellular hypoxic microenvironment under ambient atmospheric conditions

Samineh Barmaki, Ville Jokinen, Daniela Obermaier, Daria Blokhina, Matti Korhonen, Robin H. A. Ras, Jyrki Vuola, Sami Franssila, Esko Kankuri

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Acta Biomaterialia
Volume	73
Pages (from-to)	167-179
Number of pages	13
ISSN	1742-7061
DOIs	https://doi.org/10.1016/j.actbio.2018.04.007
Publication status	Published - Jun 2018
MoE publication type	A1 Journal article-refereed

Fields of Science

Hypoxia
Microenvironment
Cell culture
Microfluidic chip
Oxygen depletion
SODIUM-SULFITE
IMAGE-ANALYSIS
STEM-CELLS
CULTURE
TUMOR
OXIDATION
KINETICS
PLATFORM
BIOLOGY
HIF
220 Industrial biotechnology

Access to Document

10.1016/j.actbio.2018.04.007

1_s2.0_S1742706118301971_mainAccepted author manuscript, 2.52 MBLicence: CC BY-NC-ND
1-s2.0-S1742706118301971-mainFinal published version, 3.08 MB

Cite this

@article{48e58c8099b849b980fa1eea5e95cfe3,

title = "A microfluidic oxygen sink to create a targeted cellular hypoxic microenvironment under ambient atmospheric conditions",

keywords = "Hypoxia, Microenvironment, Cell culture, Microfluidic chip, Oxygen depletion, SODIUM-SULFITE, IMAGE-ANALYSIS, STEM-CELLS, CULTURE, TUMOR, OXIDATION, KINETICS, PLATFORM, BIOLOGY, HIF, 220 Industrial biotechnology",

author = "Samineh Barmaki and Ville Jokinen and Daniela Obermaier and Daria Blokhina and Matti Korhonen and Ras, {Robin H. A.} and Jyrki Vuola and Sami Franssila and Esko Kankuri",

year = "2018",

month = jun,

doi = "10.1016/j.actbio.2018.04.007",

language = "English",

volume = "73",

pages = "167--179",

journal = "Acta Biomaterialia",

issn = "1742-7061",

publisher = "ELSEVIER SCI IRELAND LTD",

}

TY - JOUR

T1 - A microfluidic oxygen sink to create a targeted cellular hypoxic microenvironment under ambient atmospheric conditions

AU - Barmaki, Samineh

AU - Jokinen, Ville

AU - Obermaier, Daniela

AU - Blokhina, Daria

AU - Korhonen, Matti

AU - Ras, Robin H. A.

AU - Vuola, Jyrki

AU - Franssila, Sami

AU - Kankuri, Esko

PY - 2018/6

Y1 - 2018/6

KW - Hypoxia

KW - Microenvironment

KW - Cell culture

KW - Microfluidic chip

KW - Oxygen depletion

KW - SODIUM-SULFITE

KW - IMAGE-ANALYSIS

KW - STEM-CELLS

KW - CULTURE

KW - TUMOR

KW - OXIDATION

KW - KINETICS

KW - PLATFORM

KW - BIOLOGY

KW - HIF

KW - 220 Industrial biotechnology

U2 - 10.1016/j.actbio.2018.04.007

DO - 10.1016/j.actbio.2018.04.007

M3 - Article

VL - 73

SP - 167

EP - 179

JO - Acta Biomaterialia

JF - Acta Biomaterialia

SN - 1742-7061

ER -