A New Highly Reactive and Low Lipophilicity Fluorine-18 Labeled Tetrazine Derivative for Pretargeted PET Imaging

Outi Keinänen, Xiang-Guo Li, Naveen K. Chenna, Dave Lumen, Jennifer Ott, Carla F. M. Molthoff, Mirkka Sarparanta, Kerttuli Helariutta, Tapani Vuorinen, Albert D. Windhorst, Anu J. Airaksinen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalACS Medicinal Chemistry Letters
Volume7
Issue number1
Pages (from-to)62-66
Number of pages5
ISSN1948-5875
DOIs
Publication statusPublished - Jan 2016
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Bioorthogonal chemistry
  • click chemistry
  • kinetics
  • PET imaging
  • tetrazine
  • POSITRON-EMISSION-TOMOGRAPHY
  • PLASMA-PROTEIN BINDING
  • IN-VIVO CHEMISTRY
  • DRUG DISCOVERY
  • BIOORTHOGONAL CHEMISTRY
  • CLICK CHEMISTRY
  • PEPTIDE
  • CYCLOADDITION
  • STABILITY
  • LIGATION
  • 116 Chemical sciences
  • 317 Pharmacy

Activities

  • 1 Supervisor or co-supervisor of doctoral thesis

Ph.D. thesis co-supervisor

Mirkka Sarparanta (Co-supervisor)

20132018

Activity: Examination typesSupervisor or co-supervisor of doctoral thesis

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