A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat

Yulia A. Sidorova, Maxim M. Bespalov, Agnes W. Wong, Oleg Kambur, Viljami Jokinen, Tuomas O. Lilius, Ilida Suleymanova, Gunnar Karelson, Pekka V. Rauhala, Mati Karelson, Peregrine B. Osborne, Janet R. Keast, Eija A. Kalso, Mart Saarma

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number365
JournalFrontiers in Pharmacology
Volume8
Number of pages18
ISSN1663-9812
DOIs
Publication statusPublished - 21 Jun 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • neuropathic pain
  • glial cell line-derived neurotrophic factor (GDNF)
  • GDNF family ligands (GFLs)
  • artemin (ARTN)
  • small molecule RET agonist
  • GFL mimetic
  • GDNF family receptor alpha (GFR alpha)
  • receptor tyrosine kinase RET
  • SPINAL NERVE LIGATION
  • NEUROTROPHIC FACTOR
  • SYSTEMIC ARTEMIN
  • FAMILY LIGANDS
  • DRG NEURONS
  • C-RET
  • PAIN
  • INJURY
  • NGF
  • SUBPOPULATIONS
  • 317 Pharmacy
  • 1182 Biochemistry, cell and molecular biology

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