A novel uterine leiomyoma subtype exhibits NRF2 activation and mutations in genes associated with neddylation of the Cullin 3-RING E3 ligase

Miika Mehine; Terhi Ahvenainen; Sara Khamaiseh; Jouni Härkönen; Siiri Reinikka; Tuomas Heikkinen; Anna Äyräväinen; Päivi Pakarinen; Päivi Härkki; Annukka Pasanen; Anna-Liisa Levonen; Ralf Bützow; Pia Vahteristo

doi:10.1038/s41389-022-00425-3

A novel uterine leiomyoma subtype exhibits NRF2 activation and mutations in genes associated with neddylation of the Cullin 3-RING E3 ligase

Miika Mehine, Terhi Ahvenainen, Sara Khamaiseh, Jouni Härkönen, Siiri Reinikka, Tuomas Heikkinen, Anna Äyräväinen, Päivi Pakarinen, Päivi Härkki, Annukka Pasanen, Anna-Liisa Levonen, Ralf Bützow, Pia Vahteristo

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	52
Journal	Oncogenesis
Volume	11
Issue number	1
Number of pages	10
ISSN	2157-9024
DOIs	https://doi.org/10.1038/s41389-022-00425-3
Publication status	Published - 7 Sep 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

BENIGN METASTASIZING LEIOMYOMA
ANALYSIS TOOLKIT
HEREDITARY
EXPRESSION
INHIBITOR
FUMARASE
TUMORS
3122 Cancers

Access to Document

10.1038/s41389-022-00425-3

s41389-022-00425-3Final published version, 2.54 MBLicence: CC BY

Cite this

Mehine, M., Ahvenainen, T., Khamaiseh, S., Härkönen, J., Reinikka, S., Heikkinen, T., Äyräväinen, A., Pakarinen, P., Härkki, P., Pasanen, A., Levonen, A-L., Bützow, R., & Vahteristo, P. (2022). A novel uterine leiomyoma subtype exhibits NRF2 activation and mutations in genes associated with neddylation of the Cullin 3-RING E3 ligase. Oncogenesis, 11(1), [52]. https://doi.org/10.1038/s41389-022-00425-3

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title = "A novel uterine leiomyoma subtype exhibits NRF2 activation and mutations in genes associated with neddylation of the Cullin 3-RING E3 ligase",

keywords = "BENIGN METASTASIZING LEIOMYOMA, ANALYSIS TOOLKIT, HEREDITARY, EXPRESSION, INHIBITOR, FUMARASE, TUMORS, 3122 Cancers",

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year = "2022",

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doi = "10.1038/s41389-022-00425-3",

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Mehine, M, Ahvenainen, T, Khamaiseh, S, Härkönen, J, Reinikka, S , Heikkinen, T , Äyräväinen, A , Pakarinen, P, Härkki, P, Pasanen, A, Levonen, A-L, Bützow, R & Vahteristo, P 2022, 'A novel uterine leiomyoma subtype exhibits NRF2 activation and mutations in genes associated with neddylation of the Cullin 3-RING E3 ligase', Oncogenesis, vol. 11, no. 1, 52. https://doi.org/10.1038/s41389-022-00425-3

TY - JOUR

T1 - A novel uterine leiomyoma subtype exhibits NRF2 activation and mutations in genes associated with neddylation of the Cullin 3-RING E3 ligase

AU - Mehine, Miika

AU - Ahvenainen, Terhi

AU - Khamaiseh, Sara

AU - Härkönen, Jouni

AU - Reinikka, Siiri

AU - Heikkinen, Tuomas

AU - Äyräväinen, Anna

AU - Pakarinen, Päivi

AU - Härkki, Päivi

AU - Pasanen, Annukka

AU - Levonen, Anna-Liisa

AU - Bützow, Ralf

AU - Vahteristo, Pia

PY - 2022/9/7

Y1 - 2022/9/7

KW - BENIGN METASTASIZING LEIOMYOMA

KW - ANALYSIS TOOLKIT

KW - HEREDITARY

KW - EXPRESSION

KW - INHIBITOR

KW - FUMARASE

KW - TUMORS

KW - 3122 Cancers

U2 - 10.1038/s41389-022-00425-3

DO - 10.1038/s41389-022-00425-3

M3 - Article

VL - 11

JO - Oncogenesis

JF - Oncogenesis

SN - 2157-9024

IS - 1

M1 - 52

ER -