A putative Lynch syndrome family carrying MSH2 and MSH6 variants of uncertain significance-functional analysis reveals the pathogenic one

Jukka Kantelinen, Thomas V. O. Hansen, Minttu Kansikas, Lotte Nylandsted Krogh, Mari K. Korhonen, Saara Ollila, Minna Nystrom, Anne-Marie Gerdes, Reetta Kariola

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalFamilial Cancer
Volume2011
Issue number10
Pages (from-to)515-520
Number of pages6
ISSN1389-9600
DOIs
Publication statusPublished - 2011
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Functional analysis
  • Lynch syndrome
  • MSH2
  • MSH6
  • Variants of uncertain significance (VUS)
  • NONPOLYPOSIS COLORECTAL-CANCER
  • DNA MISMATCH REPAIR
  • GERMLINE MUTATIONS
  • MISSENSE MUTATIONS
  • MUTS-ALPHA
  • HNPCC
  • PROTEIN
  • CELLS
  • GENE
  • 1184 Genetics, developmental biology, physiology

Cite this

@article{55c905e73b12432baf6b6603b9691436,
title = "A putative Lynch syndrome family carrying MSH2 and MSH6 variants of uncertain significance-functional analysis reveals the pathogenic one",
keywords = "Functional analysis, Lynch syndrome, MSH2, MSH6, Variants of uncertain significance (VUS), NONPOLYPOSIS COLORECTAL-CANCER, DNA MISMATCH REPAIR, GERMLINE MUTATIONS, MISSENSE MUTATIONS, MUTS-ALPHA, HNPCC, PROTEIN, CELLS, GENE, 1184 Genetics, developmental biology, physiology",
author = "Jukka Kantelinen and Hansen, {Thomas V. O.} and Minttu Kansikas and Krogh, {Lotte Nylandsted} and Korhonen, {Mari K.} and Saara Ollila and Minna Nystrom and Anne-Marie Gerdes and Reetta Kariola",
year = "2011",
doi = "10.1007/s10689-011-9436-z",
language = "English",
volume = "2011",
pages = "515--520",
journal = "Familial Cancer",
issn = "1389-9600",
publisher = "Springer",
number = "10",

}

A putative Lynch syndrome family carrying MSH2 and MSH6 variants of uncertain significance-functional analysis reveals the pathogenic one. / Kantelinen, Jukka; Hansen, Thomas V. O.; Kansikas, Minttu; Krogh, Lotte Nylandsted; Korhonen, Mari K.; Ollila, Saara; Nystrom, Minna; Gerdes, Anne-Marie; Kariola, Reetta.

In: Familial Cancer, Vol. 2011, No. 10, 2011, p. 515-520.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - A putative Lynch syndrome family carrying MSH2 and MSH6 variants of uncertain significance-functional analysis reveals the pathogenic one

AU - Kantelinen, Jukka

AU - Hansen, Thomas V. O.

AU - Kansikas, Minttu

AU - Krogh, Lotte Nylandsted

AU - Korhonen, Mari K.

AU - Ollila, Saara

AU - Nystrom, Minna

AU - Gerdes, Anne-Marie

AU - Kariola, Reetta

PY - 2011

Y1 - 2011

KW - Functional analysis

KW - Lynch syndrome

KW - MSH2

KW - MSH6

KW - Variants of uncertain significance (VUS)

KW - NONPOLYPOSIS COLORECTAL-CANCER

KW - DNA MISMATCH REPAIR

KW - GERMLINE MUTATIONS

KW - MISSENSE MUTATIONS

KW - MUTS-ALPHA

KW - HNPCC

KW - PROTEIN

KW - CELLS

KW - GENE

KW - 1184 Genetics, developmental biology, physiology

U2 - 10.1007/s10689-011-9436-z

DO - 10.1007/s10689-011-9436-z

M3 - Article

VL - 2011

SP - 515

EP - 520

JO - Familial Cancer

JF - Familial Cancer

SN - 1389-9600

IS - 10

ER -