A randomized, controlled multicenter feasibility pilot trial on imaging confirmed uncomplicated acute appendicitis: Appendectomy vs. symptomatic treatment in pediatric patients (the APPSYPP) trial study protocol

Jenny Puputti; Janne S. Suominen; Topi Luoto; Pauliina Hiltunen; Liisi Ripatti; Marianna Nikoskelainen; Susanna Nuutinen; Juha-Jaakko Sinikumpu; Esko Tahkola; Susanna Porela-Tiihonen; Saija Hurme; Paulina Salminen; Mikko P. Pakarinen

doi:10.1016/j.cct.2022.106970

A randomized, controlled multicenter feasibility pilot trial on imaging confirmed uncomplicated acute appendicitis: Appendectomy vs. symptomatic treatment in pediatric patients (the APPSYPP) trial study protocol

Jenny Puputti, Janne S. Suominen, Topi Luoto, Pauliina Hiltunen, Liisi Ripatti, Marianna Nikoskelainen, Susanna Nuutinen, Juha-Jaakko Sinikumpu, Esko Tahkola, Susanna Porela-Tiihonen, Saija Hurme, Paulina Salminen, Mikko P. Pakarinen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	106970
Journal	Contemporary Clinical Trials
Volume	123
Number of pages	9
ISSN	1551-7144
DOIs	https://doi.org/10.1016/j.cct.2022.106970
Publication status	Published - Dec 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

3123 Gynaecology and paediatrics
3126 Surgery, anesthesiology, intensive care, radiology
317 Pharmacy

Access to Document

10.1016/j.cct.2022.106970

AcceptedManuscript_draftAccepted author manuscript, 2.37 MBLicence: CC BY-NC-ND

Cite this

Puputti, J., Suominen, J. S., Luoto, T., Hiltunen, P., Ripatti, L., Nikoskelainen, M., Nuutinen, S., Sinikumpu, J.-J., Tahkola, E., Porela-Tiihonen, S., Hurme, S., Salminen, P., & Pakarinen, M. P. (2022). A randomized, controlled multicenter feasibility pilot trial on imaging confirmed uncomplicated acute appendicitis: Appendectomy vs. symptomatic treatment in pediatric patients (the APPSYPP) trial study protocol. Contemporary Clinical Trials, 123, Article 106970. https://doi.org/10.1016/j.cct.2022.106970

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title = "A randomized, controlled multicenter feasibility pilot trial on imaging confirmed uncomplicated acute appendicitis: Appendectomy vs. symptomatic treatment in pediatric patients (the APPSYPP) trial study protocol",

keywords = "3123 Gynaecology and paediatrics, 3126 Surgery, anesthesiology, intensive care, radiology, 317 Pharmacy",

author = "Jenny Puputti and Suominen, {Janne S.} and Topi Luoto and Pauliina Hiltunen and Liisi Ripatti and Marianna Nikoskelainen and Susanna Nuutinen and Juha-Jaakko Sinikumpu and Esko Tahkola and Susanna Porela-Tiihonen and Saija Hurme and Paulina Salminen and Pakarinen, {Mikko P.}",

year = "2022",

month = dec,

doi = "10.1016/j.cct.2022.106970",

language = "English",

volume = "123",

journal = "Contemporary Clinical Trials",

issn = "1551-7144",

publisher = "EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC",

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Puputti, J, Suominen, JS, Luoto, T, Hiltunen, P, Ripatti, L, Nikoskelainen, M, Nuutinen, S, Sinikumpu, J-J, Tahkola, E, Porela-Tiihonen, S, Hurme, S, Salminen, P & Pakarinen, MP 2022, 'A randomized, controlled multicenter feasibility pilot trial on imaging confirmed uncomplicated acute appendicitis: Appendectomy vs. symptomatic treatment in pediatric patients (the APPSYPP) trial study protocol', Contemporary Clinical Trials, vol. 123, 106970. https://doi.org/10.1016/j.cct.2022.106970

A randomized, controlled multicenter feasibility pilot trial on imaging confirmed uncomplicated acute appendicitis: Appendectomy vs. symptomatic treatment in pediatric patients (the APPSYPP) trial study protocol. / Puputti, Jenny; Suominen, Janne S.; Luoto, Topi et al.
In: Contemporary Clinical Trials, Vol. 123, 106970, 12.2022.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - A randomized, controlled multicenter feasibility pilot trial on imaging confirmed uncomplicated acute appendicitis

T2 - Appendectomy vs. symptomatic treatment in pediatric patients (the APPSYPP) trial study protocol

AU - Puputti, Jenny

AU - Suominen, Janne S.

AU - Luoto, Topi

AU - Hiltunen, Pauliina

AU - Ripatti, Liisi

AU - Nikoskelainen, Marianna

AU - Nuutinen, Susanna

AU - Sinikumpu, Juha-Jaakko

AU - Tahkola, Esko

AU - Porela-Tiihonen, Susanna

AU - Hurme, Saija

AU - Salminen, Paulina

AU - Pakarinen, Mikko P.

PY - 2022/12

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KW - 3123 Gynaecology and paediatrics

KW - 3126 Surgery, anesthesiology, intensive care, radiology

KW - 317 Pharmacy

U2 - 10.1016/j.cct.2022.106970

DO - 10.1016/j.cct.2022.106970

M3 - Article

C2 - 36280033

SN - 1551-7144

VL - 123

JO - Contemporary Clinical Trials

JF - Contemporary Clinical Trials

M1 - 106970

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Puputti J, Suominen JS, Luoto T, Hiltunen P, Ripatti L, Nikoskelainen M et al. A randomized, controlled multicenter feasibility pilot trial on imaging confirmed uncomplicated acute appendicitis: Appendectomy vs. symptomatic treatment in pediatric patients (the APPSYPP) trial study protocol. Contemporary Clinical Trials. 2022 Dec;123:106970. doi: 10.1016/j.cct.2022.106970