A scaffold replacement approach towards new sirtuin 2 inhibitors

Tina Seifert, Marcus Malo, Tarja Kokkola, E. Johanna L. Steen, Kristian Meinander, Erik A. A. Wallen, Elina M. Jarho, Kristina Luthman

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number115231
JournalBioorganic & Medicinal Chemistry
Volume28
Issue number2
Number of pages12
ISSN0968-0896
DOIs
Publication statusPublished - 15 Jan 2020
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Scaffold
  • Sirtuin
  • SIRT2
  • Inhibitor
  • Benzothiazine-1,1-dioxide
  • Benzothiadiazine-1,1-dioxides
  • Saccharin
  • Quinolin-4-one
  • Docking
  • FORCE-FIELD
  • CHROMAN-4-ONE
  • PROTEIN
  • BRAIN
  • 1182 Biochemistry, cell and molecular biology
  • 116 Chemical sciences
  • 317 Pharmacy

Cite this