A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis

Intl Multiple Sclerosis Genetics, Lohith Madireddy, Niklaos A. Patsopoulos, Aarno Palotie

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number2236
JournalNature Communications
Volume10
Number of pages12
ISSN2041-1723
DOIs
Publication statusPublished - 20 May 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • GENOME-WIDE ASSOCIATION
  • POLYGENIC RISK SCORE
  • GWAS
  • EXPRESSION
  • CYTOSCAPE
  • PATHWAY
  • 3111 Biomedicine
  • 1184 Genetics, developmental biology, physiology

Cite this

Intl Multiple Sclerosis Genetics ; Madireddy, Lohith ; Patsopoulos, Niklaos A. ; Palotie, Aarno. / A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis. In: Nature Communications. 2019 ; Vol. 10.
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author = "{Intl Multiple Sclerosis Genetics} and Lohith Madireddy and Patsopoulos, {Niklaos A.} and Chris Cotsapas and Bos, {Steffan D.} and Ashley Beecham and Jacob McCauley and Kicheol Kim and Xiaoming Jia and Adam Santaniello and Caillier, {Stacy J.} and Andlauer, {Till F. M.} and Barcellos, {Lisa F.} and Tone Berge and Luisa Bernardinelli and Filippo Martinelli-Boneschi and Booth, {David R.} and Farren Briggs and Celius, {Elisabeth G.} and Manuel Comabella and Giancarlo Comi and Cree, {Bruce A. C.} and Sandra D'Alfonso and Katrina Dedham and Pierre Duquette and Dardiotis Efthimios and Federica Esposito and Bertrand Fontaine and Christiane Gasperi and An Goris and Benedicte Dubois and Pierre-Antoine Gourraud and Georgios Hadjigeorgiou and Jonathan Haines and Clive Hawkins and Bernhard Hemmer and Rogier Hintzen and Dana Horakova and Noriko Isobe and Seema Kalra and Jun-ichi Kira and Michael Khalil and Ingrid Kockum and Lill, {Christina M.} and Lincoln, {Matthew R.} and Felix Luessi and Roland Martin and Annette Oturai and Aarno Palotie and Pericak-Vance, {Margaret A.} and Janna Saarela",
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A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis. / Intl Multiple Sclerosis Genetics; Madireddy, Lohith; Patsopoulos, Niklaos A.; Palotie, Aarno.

In: Nature Communications, Vol. 10, 2236, 20.05.2019.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis

AU - Intl Multiple Sclerosis Genetics

AU - Madireddy, Lohith

AU - Patsopoulos, Niklaos A.

AU - Cotsapas, Chris

AU - Bos, Steffan D.

AU - Beecham, Ashley

AU - McCauley, Jacob

AU - Kim, Kicheol

AU - Jia, Xiaoming

AU - Santaniello, Adam

AU - Caillier, Stacy J.

AU - Andlauer, Till F. M.

AU - Barcellos, Lisa F.

AU - Berge, Tone

AU - Bernardinelli, Luisa

AU - Martinelli-Boneschi, Filippo

AU - Booth, David R.

AU - Briggs, Farren

AU - Celius, Elisabeth G.

AU - Comabella, Manuel

AU - Comi, Giancarlo

AU - Cree, Bruce A. C.

AU - D'Alfonso, Sandra

AU - Dedham, Katrina

AU - Duquette, Pierre

AU - Efthimios, Dardiotis

AU - Esposito, Federica

AU - Fontaine, Bertrand

AU - Gasperi, Christiane

AU - Goris, An

AU - Dubois, Benedicte

AU - Gourraud, Pierre-Antoine

AU - Hadjigeorgiou, Georgios

AU - Haines, Jonathan

AU - Hawkins, Clive

AU - Hemmer, Bernhard

AU - Hintzen, Rogier

AU - Horakova, Dana

AU - Isobe, Noriko

AU - Kalra, Seema

AU - Kira, Jun-ichi

AU - Khalil, Michael

AU - Kockum, Ingrid

AU - Lill, Christina M.

AU - Lincoln, Matthew R.

AU - Luessi, Felix

AU - Martin, Roland

AU - Oturai, Annette

AU - Palotie, Aarno

AU - Pericak-Vance, Margaret A.

AU - Saarela, Janna

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KW - EXPRESSION

KW - CYTOSCAPE

KW - PATHWAY

KW - 3111 Biomedicine

KW - 1184 Genetics, developmental biology, physiology

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