A toddler PCV booster dose following 3 infancy priming doses increases circulating serotype-specific IGG levels but does not increase protection against carriage

Ron Dagan; Shalom Ben-Shimol; Birgit Simell; David Greenberg; Nurith Porat; Helena Käyhty; Noga Givon-Lavi

doi:10.1016/j.vaccine.2018.04.007

A toddler PCV booster dose following 3 infancy priming doses increases circulating serotype-specific IGG levels but does not increase protection against carriage

Ron Dagan, Shalom Ben-Shimol, Birgit Simell, David Greenberg, Nurith Porat, Helena Käyhty, Noga Givon-Lavi

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Vaccine
Volume	36
Issue number	20
Pages (from-to)	2774-2782
Number of pages	9
ISSN	0264-410X
DOIs	https://doi.org/10.1016/j.vaccine.2018.04.007
Publication status	Published - 11 May 2018
MoE publication type	A1 Journal article-refereed

Fields of Science

Pneumococcal conjugate vaccines
PCV
Carriage
Serologic response
Booster
Vaccine schedule
Infants
Toddlers
PNEUMOCOCCAL CONJUGATE VACCINE
RANDOMIZED-CONTROLLED-TRIAL
STANDARD REFERENCE SERUM
NASOPHARYNGEAL CARRIAGE
STREPTOCOCCUS-PNEUMONIAE
DOSING SCHEDULES
ANTIBODY UNITS
IMMUNOGENICITY
CHILDREN
COLONIZATION
3121 General medicine, internal medicine and other clinical medicine
3111 Biomedicine

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10.1016/j.vaccine.2018.04.007

1-s2.0-S0264410X18304766-mainFinal published version, 1.36 MB

Cite this

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title = "A toddler PCV booster dose following 3 infancy priming doses increases circulating serotype-specific IGG levels but does not increase protection against carriage",

keywords = "Pneumococcal conjugate vaccines, PCV, Carriage, Serologic response, Booster, Vaccine schedule, Infants, Toddlers, PNEUMOCOCCAL CONJUGATE VACCINE, RANDOMIZED-CONTROLLED-TRIAL, STANDARD REFERENCE SERUM, NASOPHARYNGEAL CARRIAGE, STREPTOCOCCUS-PNEUMONIAE, DOSING SCHEDULES, ANTIBODY UNITS, IMMUNOGENICITY, CHILDREN, COLONIZATION, 3121 General medicine, internal medicine and other clinical medicine, 3111 Biomedicine",

author = "Ron Dagan and Shalom Ben-Shimol and Birgit Simell and David Greenberg and Nurith Porat and Helena K{\"a}yhty and Noga Givon-Lavi",

year = "2018",

month = may,

day = "11",

doi = "10.1016/j.vaccine.2018.04.007",

language = "English",

volume = "36",

pages = "2774--2782",

journal = "Vaccine",

issn = "0264-410X",

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TY - JOUR

T1 - A toddler PCV booster dose following 3 infancy priming doses increases circulating serotype-specific IGG levels but does not increase protection against carriage

AU - Dagan, Ron

AU - Ben-Shimol, Shalom

AU - Simell, Birgit

AU - Greenberg, David

AU - Porat, Nurith

AU - Käyhty, Helena

AU - Givon-Lavi, Noga

PY - 2018/5/11

Y1 - 2018/5/11

KW - Pneumococcal conjugate vaccines

KW - PCV

KW - Carriage

KW - Serologic response

KW - Booster

KW - Vaccine schedule

KW - Infants

KW - Toddlers

KW - PNEUMOCOCCAL CONJUGATE VACCINE

KW - RANDOMIZED-CONTROLLED-TRIAL

KW - STANDARD REFERENCE SERUM

KW - NASOPHARYNGEAL CARRIAGE

KW - STREPTOCOCCUS-PNEUMONIAE

KW - DOSING SCHEDULES

KW - ANTIBODY UNITS

KW - IMMUNOGENICITY

KW - CHILDREN

KW - COLONIZATION

KW - 3121 General medicine, internal medicine and other clinical medicine

KW - 3111 Biomedicine

U2 - 10.1016/j.vaccine.2018.04.007

DO - 10.1016/j.vaccine.2018.04.007

M3 - Article

VL - 36

SP - 2774

EP - 2782

JO - Vaccine

JF - Vaccine

SN - 0264-410X

IS - 20

ER -