Acidic extracellular pH promotes accumulation of free cholesterol in human monocyte-derived macrophages via inhibition of ACAT1 activity

Miriam Lee-Rueckert, Jani Lappalainen, Hannele Leinonen, Riia Plihtari, Tommy Nordström, Karl Åkerman, Katariina Öörni, Petri T. Kovanen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalAtherosclerosis
Volume312
Number of pages7
ISSN0021-9150
DOIs
Publication statusPublished - Nov 2020
MoE publication typeA1 Journal article-refereed

Fields of Science

  • ACAT1
  • Macrophages
  • Foam cells
  • Free cholesterol
  • Acidic pH
  • LOW-DENSITY-LIPOPROTEIN
  • ACYL-COENZYME
  • ATHEROSCLEROTIC LESIONS
  • ACYLTRANSFERASE
  • EXPRESSION
  • EFFLUX
  • CELLS
  • LDL
  • COA
  • IDENTIFICATION
  • 3121 Internal medicine
  • 3111 Biomedicine

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