Acute human bocavirus 1 infection in child with life-threatening bilateral bronchiolitis and right-sided pneumonia: a case report

Inga Ziemele, Man Xu, Anda Vilmane, Santa Rasa-Dzelzkaleja, Lea Hedman, Klaus Hedman, Maria Söderlund-Venermo, Zaiga Nora-Krukle, Modra Murovska, Dace Gardovska

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Human bocavirus 1 is a commonly detected human parvovirus. Many studies have shown human bocavirus 1 as a pathogen in association with acute respiratory tract infections in children. However, because human bocavirus 1 persists in the upper airways for extensive time periods after acute infection, the definition and diagnostics of acute human bocavirus 1 infection is challenging. Until now, detection of human bocavirus 1 exclusively, high viral load in respiratory samples, and viremia have been associated with a clinical picture of acute respiratory illness. There are no studies showing detection of human bocavirus 1 messenger ribonucleic acid in the peripheral blood mononuclear cells as a diagnostic marker for acute lower respiratory tract infection.
Original languageEnglish
Article number290
JournalJournal of Medical Case Reports
Volume13
Issue number1
Number of pages6
ISSN1752-1947
DOIs
Publication statusPublished - 14 Sep 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 3111 Biomedicine
  • 1183 Plant biology, microbiology, virology

Cite this

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title = "Acute human bocavirus 1 infection in child with life-threatening bilateral bronchiolitis and right-sided pneumonia: a case report",
abstract = "Human bocavirus 1 is a commonly detected human parvovirus. Many studies have shown human bocavirus 1 as a pathogen in association with acute respiratory tract infections in children. However, because human bocavirus 1 persists in the upper airways for extensive time periods after acute infection, the definition and diagnostics of acute human bocavirus 1 infection is challenging. Until now, detection of human bocavirus 1 exclusively, high viral load in respiratory samples, and viremia have been associated with a clinical picture of acute respiratory illness. There are no studies showing detection of human bocavirus 1 messenger ribonucleic acid in the peripheral blood mononuclear cells as a diagnostic marker for acute lower respiratory tract infection.",
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year = "2019",
month = "9",
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language = "English",
volume = "13",
journal = "Journal of Medical Case Reports",
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Acute human bocavirus 1 infection in child with life-threatening bilateral bronchiolitis and right-sided pneumonia: a case report. / Ziemele, Inga; Xu, Man; Vilmane, Anda; Rasa-Dzelzkaleja, Santa; Hedman, Lea; Hedman, Klaus; Söderlund-Venermo, Maria; Nora-Krukle, Zaiga; Murovska, Modra; Gardovska, Dace.

In: Journal of Medical Case Reports, Vol. 13, No. 1, 290, 14.09.2019.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Acute human bocavirus 1 infection in child with life-threatening bilateral bronchiolitis and right-sided pneumonia: a case report

AU - Ziemele, Inga

AU - Xu, Man

AU - Vilmane, Anda

AU - Rasa-Dzelzkaleja, Santa

AU - Hedman, Lea

AU - Hedman, Klaus

AU - Söderlund-Venermo, Maria

AU - Nora-Krukle, Zaiga

AU - Murovska, Modra

AU - Gardovska, Dace

PY - 2019/9/14

Y1 - 2019/9/14

N2 - Human bocavirus 1 is a commonly detected human parvovirus. Many studies have shown human bocavirus 1 as a pathogen in association with acute respiratory tract infections in children. However, because human bocavirus 1 persists in the upper airways for extensive time periods after acute infection, the definition and diagnostics of acute human bocavirus 1 infection is challenging. Until now, detection of human bocavirus 1 exclusively, high viral load in respiratory samples, and viremia have been associated with a clinical picture of acute respiratory illness. There are no studies showing detection of human bocavirus 1 messenger ribonucleic acid in the peripheral blood mononuclear cells as a diagnostic marker for acute lower respiratory tract infection.

AB - Human bocavirus 1 is a commonly detected human parvovirus. Many studies have shown human bocavirus 1 as a pathogen in association with acute respiratory tract infections in children. However, because human bocavirus 1 persists in the upper airways for extensive time periods after acute infection, the definition and diagnostics of acute human bocavirus 1 infection is challenging. Until now, detection of human bocavirus 1 exclusively, high viral load in respiratory samples, and viremia have been associated with a clinical picture of acute respiratory illness. There are no studies showing detection of human bocavirus 1 messenger ribonucleic acid in the peripheral blood mononuclear cells as a diagnostic marker for acute lower respiratory tract infection.

KW - 3111 Biomedicine

KW - 1183 Plant biology, microbiology, virology

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