Acute human bocavirus 1 infection in child with life-threatening bilateral bronchiolitis and right-sided pneumonia: a case report

Inga Ziemele, Man Xu, Anda Vilmane, Santa Rasa-Dzelzkaleja, Lea Hedman, Klaus Hedman, Maria Söderlund-Venermo, Zaiga Nora-Krukle, Modra Murovska, Dace Gardovska

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Human bocavirus 1 is a commonly detected human parvovirus. Many studies have shown human bocavirus 1 as a pathogen in association with acute respiratory tract infections in children. However, because human bocavirus 1 persists in the upper airways for extensive time periods after acute infection, the definition and diagnostics of acute human bocavirus 1 infection is challenging. Until now, detection of human bocavirus 1 exclusively, high viral load in respiratory samples, and viremia have been associated with a clinical picture of acute respiratory illness. There are no studies showing detection of human bocavirus 1 messenger ribonucleic acid in the peripheral blood mononuclear cells as a diagnostic marker for acute lower respiratory tract infection.
Original languageEnglish
Article number290
JournalJournal of Medical Case Reports
Volume13
Issue number1
Number of pages6
ISSN1752-1947
DOIs
Publication statusPublished - 14 Sep 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 3111 Biomedicine
  • 1183 Plant biology, microbiology, virology

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