Acute phase response and clinical manifestation in outbreaks of interdigital phlegmon in dairy herds

Miia Kontturi, Reijo Junni, Minna Kujala-Wirth, Erja Malinen, Eija Seuna, Sinikka Pelkonen, Timo Soveri, Heli Simojoki

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Several Finnish dairy herds have suffered from outbreaks of interdigital phlegmon (IP). In these new types of outbreaks, morbidity was high and clinical signs severe, resulting in substantial economic losses for affected farms. In our study, we visited 18 free stall dairy herds experiencing an outbreak of IP and 3 control herds without a similar outbreak. From a total of 203 sampled cows, 60 suffered from acute stage IP. We demonstrated that acute phase response of bovine IP was evident and therefore an appropriate analgesic should be administered in the treatment of affected animals. The response was most apparent in herds with high morbidity in IP and with a bacterial infection comprising Fusobacterium necrophorum and Dichelobacter nodosus, indicating that combination of these two bacterial species affect the severity of the disease.
Original languageEnglish
Article number101375
JournalComparative Immunology, Microbiology and Infectious Diseases
Volume68
Number of pages7
ISSN0147-9571
DOIs
Publication statusPublished - Feb 2020
MoE publication typeA1 Journal article-refereed

Fields of Science

  • interdigital phlegmon
  • foot rot
  • interdigital necrobacillosis
  • foul-in-the-foot
  • acute phase response
  • serum amyloid A
  • haptoglobin
  • albumin
  • infectious hoof disease
  • 413 Veterinary science

Cite this

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title = "Acute phase response and clinical manifestation in outbreaks of interdigital phlegmon in dairy herds",
abstract = "Several Finnish dairy herds have suffered from outbreaks of interdigital phlegmon (IP). In these new types of outbreaks, morbidity was high and clinical signs severe, resulting in substantial economic losses for affected farms. In our study, we visited 18 free stall dairy herds experiencing an outbreak of IP and 3 control herds without a similar outbreak. From a total of 203 sampled cows, 60 suffered from acute stage IP. We demonstrated that acute phase response of bovine IP was evident and therefore an appropriate analgesic should be administered in the treatment of affected animals. The response was most apparent in herds with high morbidity in IP and with a bacterial infection comprising Fusobacterium necrophorum and Dichelobacter nodosus, indicating that combination of these two bacterial species affect the severity of the disease.",
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language = "English",
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journal = "Comparative Immunology, Microbiology and Infectious Diseases",
issn = "0147-9571",
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Acute phase response and clinical manifestation in outbreaks of interdigital phlegmon in dairy herds. / Kontturi, Miia; Junni, Reijo; Kujala-Wirth, Minna; Malinen, Erja; Seuna, Eija; Pelkonen, Sinikka; Soveri, Timo; Simojoki, Heli.

In: Comparative Immunology, Microbiology and Infectious Diseases, Vol. 68, 101375, 02.2020.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Acute phase response and clinical manifestation in outbreaks of interdigital phlegmon in dairy herds

AU - Kontturi, Miia

AU - Junni, Reijo

AU - Kujala-Wirth, Minna

AU - Malinen, Erja

AU - Seuna, Eija

AU - Pelkonen, Sinikka

AU - Soveri, Timo

AU - Simojoki, Heli

PY - 2020/2

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AB - Several Finnish dairy herds have suffered from outbreaks of interdigital phlegmon (IP). In these new types of outbreaks, morbidity was high and clinical signs severe, resulting in substantial economic losses for affected farms. In our study, we visited 18 free stall dairy herds experiencing an outbreak of IP and 3 control herds without a similar outbreak. From a total of 203 sampled cows, 60 suffered from acute stage IP. We demonstrated that acute phase response of bovine IP was evident and therefore an appropriate analgesic should be administered in the treatment of affected animals. The response was most apparent in herds with high morbidity in IP and with a bacterial infection comprising Fusobacterium necrophorum and Dichelobacter nodosus, indicating that combination of these two bacterial species affect the severity of the disease.

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KW - foot rot

KW - interdigital necrobacillosis

KW - foul-in-the-foot

KW - acute phase response

KW - serum amyloid A

KW - haptoglobin

KW - albumin

KW - infectious hoof disease

KW - 413 Veterinary science

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JO - Comparative Immunology, Microbiology and Infectious Diseases

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