Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo

S Lindfors; Z Polianskyte-Prause; R Bouslama; E Lehtonen; M Mannerla; H Nisen; J Tienari; H Salmenkari; R Forsgard; T Mirtti; M Lehto; PH Groop; S Lehtonen

doi:10.1007/s00125-021-05473-9

Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo

S Lindfors, Z Polianskyte-Prause, R Bouslama, E Lehtonen, M Mannerla, H Nisen, J Tienari, H Salmenkari, R Forsgard, T Mirtti, M Lehto, PH Groop, S Lehtonen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Diabetologia
Volume	64
Issue number	8
Pages (from-to)	1866-1879
Number of pages	14
ISSN	0012-186X
DOIs	https://doi.org/10.1007/s00125-021-05473-9
Publication status	Published - Aug 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

Adiponectin
AdipoRon
Diabetes
Diabetic kidney disease
Inflammation
Inflammatory cytokines
LPS
Obesity
Obesity-related kidney disease
Podocyte
DIABETIC-NEPHROPATHY
KIDNEY-DISEASE
TNF-ALPHA
PROGRESSION
EXPRESSION
GENE
ALBUMINURIA
DEFICIENCY
MECHANISMS
INSIGHTS
3121 General medicine, internal medicine and other clinical medicine

Access to Document

10.1007/s00125-021-05473-9

Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivoFinal published version, 5.43 MBLicence: CC BY

Cite this

Lindfors, S., Polianskyte-Prause, Z., Bouslama, R., Lehtonen, E., Mannerla, M., Nisen, H., Tienari, J., Salmenkari, H., Forsgard, R., Mirtti, T., Lehto, M., Groop, PH., & Lehtonen, S. (2021). Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo. Diabetologia, 64(8), 1866-1879. https://doi.org/10.1007/s00125-021-05473-9

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title = "Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo",

keywords = "Adiponectin, AdipoRon, Diabetes, Diabetic kidney disease, Inflammation, Inflammatory cytokines, LPS, Obesity, Obesity-related kidney disease, Podocyte, DIABETIC-NEPHROPATHY, KIDNEY-DISEASE, TNF-ALPHA, PROGRESSION, EXPRESSION, GENE, ALBUMINURIA, DEFICIENCY, MECHANISMS, INSIGHTS, 3121 General medicine, internal medicine and other clinical medicine",

author = "S Lindfors and Z Polianskyte-Prause and R Bouslama and E Lehtonen and M Mannerla and H Nisen and J Tienari and H Salmenkari and R Forsgard and T Mirtti and M Lehto and PH Groop and S Lehtonen",

year = "2021",

month = aug,

doi = "10.1007/s00125-021-05473-9",

language = "English",

volume = "64",

pages = "1866--1879",

journal = "Diabetologia",

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Lindfors, S , Polianskyte-Prause, Z , Bouslama, R, Lehtonen, E, Mannerla, M, Nisen, H , Tienari, J , Salmenkari, H , Forsgard, R , Mirtti, T , Lehto, M , Groop, PH & Lehtonen, S 2021, 'Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo', Diabetologia, vol. 64, no. 8, pp. 1866-1879. https://doi.org/10.1007/s00125-021-05473-9

TY - JOUR

T1 - Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo

AU - Lindfors, S

AU - Polianskyte-Prause, Z

AU - Bouslama, R

AU - Lehtonen, E

AU - Mannerla, M

AU - Nisen, H

AU - Tienari, J

AU - Salmenkari, H

AU - Forsgard, R

AU - Mirtti, T

AU - Lehto, M

AU - Groop, PH

AU - Lehtonen, S

PY - 2021/8

Y1 - 2021/8

KW - Adiponectin

KW - AdipoRon

KW - Diabetes

KW - Diabetic kidney disease

KW - Inflammation

KW - Inflammatory cytokines

KW - LPS

KW - Obesity

KW - Obesity-related kidney disease

KW - Podocyte

KW - DIABETIC-NEPHROPATHY

KW - KIDNEY-DISEASE

KW - TNF-ALPHA

KW - PROGRESSION

KW - EXPRESSION

KW - GENE

KW - ALBUMINURIA

KW - DEFICIENCY

KW - MECHANISMS

KW - INSIGHTS

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.1007/s00125-021-05473-9

DO - 10.1007/s00125-021-05473-9

M3 - Article

SN - 0012-186X

VL - 64

SP - 1866

EP - 1879

JO - Diabetologia

JF - Diabetologia

IS - 8

ER -