ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors

Katja Kaipio, Ping Chen, Pia Roering, Kaisa Huhtinen, Piia Mikkonen, Päivi Östling, Laura Lehtinen, Naziha Mansuri, Taina Korpela, Swapnil Potdar, Johanna Hynninen, Annika Auranen, Seija Grénman, Krister Wennerberg, Sampsa Hautaniemi, Olli Carpén

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Pathology
Volume250
Issue number2
Pages (from-to)159-169
Number of pages11
ISSN0022-3417
DOIs
Publication statusPublished - Feb 2020
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 3122 Cancers
  • Ovarian cancer
  • stem-like cell
  • patient derived cell line
  • survival
  • drug sensitivity
  • CELLS
  • CONTRIBUTE
  • BMI-1
  • ovarian cancer
  • ALDEHYDE DEHYDROGENASE
  • MARKER
  • IDENTIFICATION
  • patient-derived cell line
  • MICROENVIRONMENT
  • EXPRESSION
  • EPITHELIAL OVARIAN
  • AURORA

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