Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy

Jayasimman Rajendran; Janne Purhonen; Saara Tegelberg; Olli-Pekka Smolander; Matthias Mörgelin; Jan Rozman; Valerie Gailus-Durner; Helmut Fuchs; Martin Hrabe de Angelis; Petri Auvinen; Eero Mervaala; Howard T. Jacobs; Marten Szibor; Vineta Fellman; Jukka Kallijärvi

doi:10.15252/emmm.201809456

Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy

Jayasimman Rajendran, Janne Purhonen, Saara Tegelberg, Olli-Pekka Smolander, Matthias Mörgelin, Jan Rozman, Valerie Gailus-Durner, Helmut Fuchs, Martin Hrabe de Angelis, Petri Auvinen, Eero Mervaala, Howard T. Jacobs, Marten Szibor, Vineta Fellman, Jukka Kallijärvi

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	9456
Journal	EMBO molecular medicine
Volume	11
Issue number	1
Number of pages	19
ISSN	1757-4676
DOIs	https://doi.org/10.15252/emmm.201809456
Publication status	Published - Jan 2019
MoE publication type	A1 Journal article-refereed

Fields of Science

BCS1L
complex III
GRACILE syndrome
mitochondrial disorder
respiratory chain
IRON-OVERLOAD
NITRIC-OXIDE
MOUSE MODEL
EXPRESSION
GENE
PROTEIN
OXYGEN
CELL
ACTIVATION
DEFECTS
3111 Biomedicine
1184 Genetics, developmental biology, physiology

Access to Document

10.15252/emmm.201809456

e9456.fullFinal published version, 4.43 MBLicence: CC BY

Cite this

Rajendran, J., Purhonen, J., Tegelberg, S., Smolander, O.-P., Mörgelin, M., Rozman, J., Gailus-Durner, V., Fuchs, H., de Angelis, M. H., Auvinen, P., Mervaala, E., Jacobs, H. T., Szibor, M., Fellman, V., & Kallijärvi, J. (2019). Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy. EMBO molecular medicine, 11(1), Article 9456. https://doi.org/10.15252/emmm.201809456

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title = "Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy",

keywords = "BCS1L, complex III, GRACILE syndrome, mitochondrial disorder, respiratory chain, IRON-OVERLOAD, NITRIC-OXIDE, MOUSE MODEL, EXPRESSION, GENE, PROTEIN, OXYGEN, CELL, ACTIVATION, DEFECTS, 3111 Biomedicine, 1184 Genetics, developmental biology, physiology",

author = "Jayasimman Rajendran and Janne Purhonen and Saara Tegelberg and Olli-Pekka Smolander and Matthias M{\"o}rgelin and Jan Rozman and Valerie Gailus-Durner and Helmut Fuchs and {de Angelis}, {Martin Hrabe} and Petri Auvinen and Eero Mervaala and Jacobs, {Howard T.} and Marten Szibor and Vineta Fellman and Jukka Kallij{\"a}rvi",

year = "2019",

month = jan,

doi = "10.15252/emmm.201809456",

language = "English",

volume = "11",

journal = "EMBO molecular medicine",

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}

Rajendran, J, Purhonen, J, Tegelberg, S, Smolander, O-P, Mörgelin, M, Rozman, J, Gailus-Durner, V, Fuchs, H, de Angelis, MH, Auvinen, P , Mervaala, E, Jacobs, HT, Szibor, M, Fellman, V & Kallijärvi, J 2019, 'Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy', EMBO molecular medicine, vol. 11, no. 1, 9456. https://doi.org/10.15252/emmm.201809456

TY - JOUR

T1 - Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy

AU - Rajendran, Jayasimman

AU - Purhonen, Janne

AU - Tegelberg, Saara

AU - Smolander, Olli-Pekka

AU - Mörgelin, Matthias

AU - Rozman, Jan

AU - Gailus-Durner, Valerie

AU - Fuchs, Helmut

AU - de Angelis, Martin Hrabe

AU - Auvinen, Petri

AU - Mervaala, Eero

AU - Jacobs, Howard T.

AU - Szibor, Marten

AU - Fellman, Vineta

AU - Kallijärvi, Jukka

PY - 2019/1

Y1 - 2019/1

KW - BCS1L

KW - complex III

KW - GRACILE syndrome

KW - mitochondrial disorder

KW - respiratory chain

KW - IRON-OVERLOAD

KW - NITRIC-OXIDE

KW - MOUSE MODEL

KW - EXPRESSION

KW - GENE

KW - PROTEIN

KW - OXYGEN

KW - CELL

KW - ACTIVATION

KW - DEFECTS

KW - 3111 Biomedicine

KW - 1184 Genetics, developmental biology, physiology

U2 - 10.15252/emmm.201809456

DO - 10.15252/emmm.201809456

M3 - Article

SN - 1757-4676

VL - 11

JO - EMBO molecular medicine

JF - EMBO molecular medicine

IS - 1

M1 - 9456

ER -