Amphetamine enantiomers inhibit homomeric alpha 7 nicotinic receptor through a competitive mechanism and within the intoxication levels in humans

Daniel R. Garton, Sharmaine G. Ross, Rafael Maldonado-Hernandez, Matthias Quick, Jose A. Lasalde-Dominicci, Jose E. Lizardi-Ortiz

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalNeuropharmacology
Volume144
Pages (from-to)172-183
Number of pages12
ISSN0028-3908
DOIs
Publication statusPublished - Jan 2019
Externally publishedYes
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Alpha 7 nicotinic acetylcholine receptor
  • Amphetamine-type stimulant
  • Pharmacological characterization
  • In silico docking analysis
  • Amphetamine-induced locomotion
  • Alpha 7 upregulation
  • ACETYLCHOLINE-RECEPTORS
  • HIPPOCAMPAL-NEURONS
  • LOCOMOTOR-ACTIVITY
  • DOPAMINE RELEASE
  • BINDING-SITES
  • METHAMPHETAMINE
  • CARBAMYLCHOLINE
  • DISPOSITION
  • ANTAGONISTS
  • MODULATION
  • 3112 Neurosciences
  • 3124 Neurology and psychiatry
  • 317 Pharmacy

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