Amyloid precursor protein alpha- and beta-cleaved ectodomains exert opposing control of cholesterol homeostasis via SREBP2

Wei Wang, Aino-Liisa Mutka, Ursula Prosenc Zmrzljak, Damjana Rozman, Heikki Tanila, Helena Gylling, Anne M. Remes, Henri J. Huttunen, Elina Ikonen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalFASEB Journal
Volume28
Issue number2
Pages (from-to)849-860
Number of pages12
ISSN0892-6638
DOIs
Publication statusPublished - Feb 2014
MoE publication typeA1 Journal article-refereed

Fields of Science

  • LDL uptake
  • APP processing
  • ALZHEIMERS-DISEASE
  • SURROGATE MARKERS
  • SITE-1 PROTEASE
  • LIPID RAFTS
  • APP
  • METABOLISM
  • TRANSPORT
  • ABSORPTION
  • PRESENILIN
  • SECRETASE
  • 3121 Internal medicine
  • 3124 Neurology and psychiatry

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