An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation

Jonna Saarimaki-Vire, Diego Balboa, Mark A. Russell, Juha Saarikettu, Matias Kinnunen, Salla Keskitalo, Amrinder Malhi, Cristina Valensisi, Colin Andrus, Solja Eurola, Heli Grym, Jarkko Ustinov, Kirmo Wartiovaara, R. David Hawkins, Olli Silvennoinen, Markku Varjosalo, Noel G. Morgan, Timo Otonkoski

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalCell Reports
Volume19
Issue number2
Pages (from-to)281-294
Number of pages14
ISSN2211-1247
DOIs
Publication statusPublished - 11 Apr 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • PLURIPOTENT STEM-CELLS
  • BETA-LIKE CELLS
  • IN-VITRO
  • ENDOCRINE PANCREAS
  • PROGENITOR CELLS
  • KNOCKOUT MICE
  • GENERATION
  • NEUROGENIN3
  • EXPRESSION
  • REVEALS
  • 3111 Biomedicine
  • 1182 Biochemistry, cell and molecular biology

Cite this

@article{376d681db6214997b443ad0fdf873b3e,
title = "An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation",
keywords = "PLURIPOTENT STEM-CELLS, BETA-LIKE CELLS, IN-VITRO, ENDOCRINE PANCREAS, PROGENITOR CELLS, KNOCKOUT MICE, GENERATION, NEUROGENIN3, EXPRESSION, REVEALS, 3111 Biomedicine, 1182 Biochemistry, cell and molecular biology",
author = "Jonna Saarimaki-Vire and Diego Balboa and Russell, {Mark A.} and Juha Saarikettu and Matias Kinnunen and Salla Keskitalo and Amrinder Malhi and Cristina Valensisi and Colin Andrus and Solja Eurola and Heli Grym and Jarkko Ustinov and Kirmo Wartiovaara and Hawkins, {R. David} and Olli Silvennoinen and Markku Varjosalo and Morgan, {Noel G.} and Timo Otonkoski",
year = "2017",
month = "4",
day = "11",
doi = "10.1016/j.celrep.2017.03.055",
language = "English",
volume = "19",
pages = "281--294",
journal = "Cell Reports",
issn = "2211-1247",
publisher = "Cell Press",
number = "2",

}

An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation. / Saarimaki-Vire, Jonna; Balboa, Diego; Russell, Mark A.; Saarikettu, Juha; Kinnunen, Matias; Keskitalo, Salla; Malhi, Amrinder; Valensisi, Cristina; Andrus, Colin; Eurola, Solja; Grym, Heli; Ustinov, Jarkko; Wartiovaara, Kirmo; Hawkins, R. David; Silvennoinen, Olli; Varjosalo, Markku; Morgan, Noel G.; Otonkoski, Timo.

In: Cell Reports, Vol. 19, No. 2, 11.04.2017, p. 281-294.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation

AU - Saarimaki-Vire, Jonna

AU - Balboa, Diego

AU - Russell, Mark A.

AU - Saarikettu, Juha

AU - Kinnunen, Matias

AU - Keskitalo, Salla

AU - Malhi, Amrinder

AU - Valensisi, Cristina

AU - Andrus, Colin

AU - Eurola, Solja

AU - Grym, Heli

AU - Ustinov, Jarkko

AU - Wartiovaara, Kirmo

AU - Hawkins, R. David

AU - Silvennoinen, Olli

AU - Varjosalo, Markku

AU - Morgan, Noel G.

AU - Otonkoski, Timo

PY - 2017/4/11

Y1 - 2017/4/11

KW - PLURIPOTENT STEM-CELLS

KW - BETA-LIKE CELLS

KW - IN-VITRO

KW - ENDOCRINE PANCREAS

KW - PROGENITOR CELLS

KW - KNOCKOUT MICE

KW - GENERATION

KW - NEUROGENIN3

KW - EXPRESSION

KW - REVEALS

KW - 3111 Biomedicine

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1016/j.celrep.2017.03.055

DO - 10.1016/j.celrep.2017.03.055

M3 - Article

VL - 19

SP - 281

EP - 294

JO - Cell Reports

JF - Cell Reports

SN - 2211-1247

IS - 2

ER -